Risk of acute hepatic insufficiency in children due to chronic accidental overdose of paracetamol (acetaminophen);Risico van acute leverinsufficiëntie bij kinderen door chronische accidentele overdosering van paracetamol

Nederlands Tijdschrift voor Geneeskunde

Volumn 151, Issue 16, 2007, Pages 897-900

  Hameleers Snijders, P ^a   Hogeveen, M ^a   Smeitink, J A M ^a   Kramers, C ^a   Draaisma, J M Th ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AMINOTRANSFERASE; BILIRUBIN; GLUCOSE; PARACETAMOL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CASE REPORT; CLINICAL FEATURE; DRUG OVERDOSE; FEMALE; HUMAN; HYPOGLYCEMIA; INTOXICATION; LIVER FAILURE; LIVER TOXICITY; PATHOGENESIS; PRESCHOOL CHILD; RISK ASSESSMENT;

ACETAMINOPHEN; ACETYLCYSTEINE; ANALGESICS, NON-NARCOTIC; CHILD, PRESCHOOL; FEMALE; FREE RADICAL SCAVENGERS; HUMANS; LIVER; LIVER FAILURE, ACUTE; OVERDOSE; PROGNOSIS; TRANSAMINASES;

EID: 34248221123     PISSN: 00282162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Nationaal Vergiftigingen Informatie Centrum (NVIC). Acute vergiftigingen bij mens en dier; jaaroverzicht 2003. Bilthoven: NVIC/RIVM; 2004.
2. Daly FF, O'Malley GF, Heard K, Bogdan GM, Dart RC. Prospective evaluation of repeated supratherapeutic acetaminophen (paracetamol) ingestion. Ann Emerg Med. 2004;44:393-8.
3. Kozer E, McGuigan M. Approaches toward repeated supratherapeutic doses of paracetamol in children: a survey of medical directors of poison centres in North America and Europe. Drug Saf. 2002;25: 613-7.
4. Rumack BH, Matthew H. Acetaminophen poisoning and toxicity. Pediatrics. 1975;55:871-6.
5. Arana A, Morton NS, Hansen TG. Treatment with paracetamol in infants. Acta Anaesthesiol Scand. 2001;45:20-9.
6. Vale JA, Proudfoot AT. Paracetamol (acetaminophen) poisoning. Lancet. 1995;346:547-52.
7. Anderson BJ. What we don't know about paracetamol in children. Paediatr Anaesth. 1998;8:451-60.
8. Miles FK, Kamath R, Dorney SF, Gaskin KJ, O'Loughlin EV. Accidental paracetamol overdosing and fulminant hepatic failure in children. Med J Aust. 1999;171:472-5.
9. Kearns GL, Leeder JS, Wasserman GS. Acetaminophen overdose with therapeutic intent. J Pediatr. 1998;132:5-8.
10. Heubi JE, Barbacci MB, Zimmerman HJ. Therapeutic misadventures with acetaminophen: hepatotoxicity after multiple doses in children. J Pediatr. 1998;132:22-7.
11. Alonso EM, Sokol RJ, Hart J, Tyson RW, Narkewicz MR, Whitington PF. Fulminant hepatitis associated with centrilobular necrosis in young children. J Pediatr. 1995;127:888-94.
12. Watson WA, Litovitz TL, Rodgers jr GC, Klein-Schwartz W, Youniss J, Rose SR, et al. 2002 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 2003;21:353-421.
13. Douidar SM, al-Khalil I, Habersang RW. Severe hepatotoxicity, acute renal failure, and pancytopenia in a young child after repeated acetaminophen overdosing. Clin Pediatr. 1994;33:42-5.
14. Harrison PM, Keays R, Bray GP, Alexander GJM, Williams R. Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. Lancet. 1990;335:1572-3.