Fish micronucleus assay: A sensitive tool for ecogenotoxicity studies

Journal of Ecophysiology and Occupational Health

Volumn 6, Issue 3-4, 2006, Pages 143-147

  Chaudhary, Rakhi ^a   Pandey, Sanjay ^b   Kushwaha, Basdeo ^b   Gaur, K K ^a   Nagpure, N S ^b  

^a R B S COLLEGE   (India)

^b NATIONAL BUREAU OF FISH GENETIC RESOURCES   (India)

Author keywords

Anthropogenic; Aquatic; Chromosomal; Ecotoxigenecity; Micronucleus

Indexed keywords

ARTICLE; ECOTOXICITY; ECOTOXICOLOGY; FISH; GENOTOXICITY; MICRONUCLEUS; MUTAGENESIS; NONHUMAN; TOXICITY TESTING; WATER POLLUTANT; WATER POLLUTION;

EID: 34248185154     PISSN: 09724397     EISSN: 0974-0805     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Al-Sabti K. Comparative micronucleated erythrocyte cell induction in three cyprinids by five carcinogenic- mutagenic chemicals.Cytobios. (1986,) 47 (190-191), 147-154.
2. Al-Sabti, K. and Metcalfe, C.D. (1995) Fish micronuclei for assessing genotoxicity in water. Mutat.Res., 343, 121-135.
3. Buschini A, Martino A., Gustavino V., Monfrinotti M, Poli P,Rossi C, Santoro M, Dorr A J, Rizzoni M. (2004). Comet assay and micronucleus test in circulating erythrocytes of Cyprinus carpio specimen exposed in situ to lake water treated with disinfectants potabilization. Mutat Res. 557, 119-129
4. Cavas T. Ergene-Gozukara S. (2003). Evaluation of the genotoxic potential of lambda-cyhalothri using nuclear and nucleolar biomarkers on fish cells. Mutat Res. 534, 93-96
5. Das, R.K. and Nanda, N. K. (1986). Induction of micronuclei in peripheral erythrocytes of fish H. fossilis by mitomycin C and paper mill effluent. Mutat. Res. 175, 67-76.
6. De Flora, S., Vigano L., D'Agostini, F., Camoirano, A., Bagnasco, M., Bennicelli, C., Melodia, F. and Arillo, A. (1993) Multiple genotoxicity biomarkers in fish exposed in situ to polluted river water. Mutat. Res. 319, 167-177.
7. 450 IAI) in lives microsomes from different fish species and rat. Fish Physiol. Chem., 9, 1-13.
8. Gravato C, Santos M A. (2003) Genotoxicity biomarkers association with B (a) P biotransformationin Dicentrarchus labrax L. Ecotoxicol Environ Saf. 55, 352-358
9. Gravato C, Santos M A (2002) Beta-naphthoflavone liver EROD and erythocytic nuclear abnormality induction in juvenile Dicentrarchus labrax L. Ecotoxicol. Environ. Saf. 52, 69-74.
10. Gravato C., Santos MA.(2003) Dicentrarchus labrax biotransformation and genotoxicity responses after exposure to a secondary treated industrial/ urban effluent. Ecotoxicol. Environ. Saf, 55, 300-306.
11. Grisolia, C.K. and Cordeiro, C.M.T. (2000) Variability in micronucleus induction with different mutagens applied to several species of fishes. Genet. Mol. Biol., 23, 235-239.
12. Hayashi, M., Ueda, T., Uyeno, L., Wada, K., Kinae, N., Saotome, K., Tanaka, N., Takai, A., Sasaki, Y.F., Asano, N., Sifuni, T. and Ojima, Y. (1998) Development of genotoxicity assay systems that use aquatic organisms. Mutat. Res., 399, 125-133.
13. Heddle et al., 1993 Micronucleus test as an index of cytogenetic damage present, past and future. Environ. Mol. Mutagen, 18, 272-291
14. Hooftman, R.N. and de-Raat, W.K. (1982) Induction of nuclear anomalies (micronuclei) in the peripheral blood erythrocytes of the eastern mud minnow Umbra pygmea by EMS. Mutat. Res., 104, 147.
15. Kligerman, A.D., Bloom, S.E. and Howell, W.M. (1975) Umbra limi; A model for the study of chromosomal aberrations in fishes. Mutat. Res., 31, 225-233.
16. Klingerman, A., (1982) Fishes as a biological detector of the effect of genotoxic agents Heddle (Ed.) Mutagenicity, New horizons in genetic Toxicology; Acadmic Press New York, 435-453.
17. Landolt, M.L., Kocan, R.M. (1983) Fish cell cytogenetics: A measure of the genotoxic effects of environmental pollutants. In: Nriago, J.O. (Ed.). "Advances in Environmental Science and Technology" New York Plenum Press. 335-353.
18. Manna, G.K. and Sadhukhan, A. (1986 a) Use of cells of gills and kidney of Tilapia fish in micronucleus test. Current Sci. 55, 498-50.
19. Manna, G.K, Banerjee, G. and Gupta, S.M.(1985) Micronuclei test in the peripheral erythrocytes of exotic fish Oreochromis mossambicus. The nucleus, 28, 176-179.
20. Mersch J., and Beauvais, M. N. (1997). The micronucleus assay in fresh water mussel, Dreissena polymorpha, to in-situ monitor genotoxicity in fresh water environments. Mutat. Res. 393, 141-149.
21. Natarajan, A.T., Boei, J.J., Darroudi, F., Van Diemen, P.C., Dulout, F., Hande, M.P. and Ramalho, A.T. (1996) Current cytogenetic methods for detecting exposure and effects of mutagens and carcinogens. Environ Health Perspect., 104, 445-8.
22. O,E,C,D, (1997) Guidelines for testing of chemicals. Mammalian erythrocyte micronucleus test. Guide line. 474.
23. Powers, D. A.(1989). Fish as model systems. Science 246, 353-358.
24. Hooftman, R.N. and Vink G.J. (1981) Cytogenetic effects on the eastern mudminnow Umbra pigmea exposed to ethyl methanesulfonate, benzo [a] pyrene and river water. Ecotoxicol. Environ. Saf. 5, 261-269
25. Rodriguez Cea A, Ayllon F, Garcia Vazquez E. (2003) Micronucleus test in fresh water fish species: an evaluation of its sensitivity for application in field surveys. Ecotoxicol. Environ. Saf. 56, 442-448.
26. Rodriquez-Cea A, Ayllon F, Garcia-Vazquez E. (2003) Micronucleus test in fresh water species:an evaluation of its sensitivity for application in field surveys. Ecotoxical Environ Saf. 56, 442-448
27. De Flora S.L., Vigano A. F., Agostini D, Camoirana M., Bagnasco C, Bennecelli F., Melodia F., and Arillo A. (1993) Multiple genotoxicity biomarkers in fish exposed in situ to polluted river water. Mutat.Res. 319, 167-177.
28. Minissi S., Ciccotti E., and Rizzoni M. (1996) Micronucleus test in erythocytes of Barbus plebejus (Teleostei pisces) from two natural environments. A bioassay for the in situ detection of mutagens in fresh water. Mutat. Res. 367, 245-251
29. Sanchez-Galen S., Lindo A.R., Izquierdo J. J., and Garcia-Vazquez E. (1998) Micronuclei and fluctuating asymmetry in brown trout (Salmo trutta); complementry methods to biomonitor freshwater ecosystems. Mutat. Res. 412, 219-225.
30. Schmid, W. (1976) Micronucleus test for cytogenetic analysis. In: Hollaender, A. (Ed.) Chemical Mutagens: Principals and methods for their detection, Vol. 4 Plenum, New York: 31-53.
31. Schroder, T. M. (1966) Cytogenetische and cytologische befunde bei enzymopenischen panmyelo pathien and pancytopenien (Familiare Panmyelopathien fanconi glutathionreduktasemangel anamie megaloblastare Vitamin B folsauremangel anamie). Humangeneik, 2, 268.
32. Thomas P. Umegaki K, Fenech M. (2003). Nucleoplasms bridges are a sensitive measure of chromosome rearrangement in the cytokinesis- block micronucleus assay. Mutagenesis 18, 187-94.
33. Vanparys, P. Dekudt, G., Vermeiren, F. Sysmans, M. and Marsboon. R (1992). Sampling times in micronucleus testing. Mutat. Res. 282, 191-196
34. W. Schmid, (1975) The micronucleus test. Mutat. Res., 319, 15.
35. Walton D G, Acton A B, Stich H F. (1984) Comparision of DNA-repair synthesis, chromosome aberrations and induction of micronuclei in cultured human fibroblasts, Chinese hamster ovary and central mudminnow (Umbra linni) cells exposed to chemical mutagens. Mutat. Res. 129, 129-36.
36. Williams, R.C. and Metcalfe, C.D. (1992) Development of an in vivo hepatic micronucleus assay with rainbow trout. Aquatic toxicology, 23, 193-202.