Hydrodynamics, mass transfer and rheological studies of gibberellic acid production in an airlift bioreactor

World Journal of Microbiology and Biotechnology

Volumn 23, Issue 5, 2007, Pages 615-623

  Chavez Parga, M C ^a   Gonzalez Ortega, O ^a   Negrete Rodriguez, M L X ^a   Medina Torres, L ^a,b   Silva, Eleazar M Escamilla ^a  

^a DEPARTAMENTO DE INGENIERÍA QUÍMICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Airlift; Gibberellic acid; Hydrodynamics; Mass transfer and rheology

Indexed keywords

BIOREACTORS; HYDRODYNAMICS; MASS TRANSFER; MATHEMATICAL MODELS; RHEOLOGY; VISCOSITY;

AIRLIFT; AIRLIFT BIOREACTOR; GIBBERELLIC ACIDS; PHYSICAL TRANSPORT PROCESSES;

CARBOXYLIC ACIDS;

FUNGI; GIBBERELLA FUJIKUROI;

EID: 34248172387     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11274-006-9270-x     Document Type: Article

References (36)

1. Abashar ME, Narsingh U, Rouillard AE, Judd R (1998) Hydrodynamic flow regimes, gas holdup, and liquid circulation in airlift reactors. Ind Eng Chem Res 37:1251-1259
2. Akita K, Yoshida F (1973) Gas holdup and volumetric mass transfer coefficient in bubble columns. Effects of liquid properties. Ind Eng Chem Process Des Develop 12:76-80
3. Al-Masry WA, Dukkan AR (1998) Hydrodynamics and mass transfer studies in a pilot-plant airlift reactor: non-Newtonian systems. Ind Eng Chem Res 37:41-48
4. La) prediction in tower bioreactors utilizing immobilized cells. Bioprocess Eng 22:181-184
5. Barrow A, Jefferys EG, Nixon IS (1960) Process for the production of gibberellic acid. ICI Patent GB 838,032
6. Brito-De la Fuente E, Nava JA, López LM, Medina L, Ascanio G, Tanguy PA (1998) Process viscometry of complex fluids and suspensions with helical ribbon agitators. Can J Chem Eng 76:689-695
7. Brückner B, Blechschmidt D (1991) The gibberellin fermentation. Crit Rev Biotechnol 11:163-192
8. Chavez MC (2005) Producción de ácido giberélico en un biorreactor airlift. Ph.D. Thesis, Instituto Tecnológico de Celaya, Celaya, Gto., México
9. Chavez-Parga MC, Gonzalez-Ortega O, Sanchez-Cornejo G, Negrete-Rodriguez MLX, Gonzalez-Alatorre G, Escamilla-Silva EM (2005) Mathematical description of bikaverin production in a fluidized bed bioreactor. World J Microbiol Biotechnol 21:683-688
10. Chisti MY (1989) Airlift bioreactor. Elsevier Appl. Science London-New York
11. Choi KH, Chisti Y, Moo-Young M (1996) Comparative evaluation of hydrodynamic and gas-liquid mass transfer characteristics in bubble column and airlift slurry reactors. Biochem Eng J 62:223-229
12. Escamilla-Silva EM, Dendooven L, Magaña IP, Parra-Saldivar R, De la Torre M (2000) Optimization of Gibberellic acid production by immobilized Gibberella fujikuroi mycelium in fluidized bioreactors. J Biotechnol 76:147-155
13. Freitas C, Teixeira JA (1998) Hydrodynamic studies in an airlift reactor with an enlarged degassing zone. Bioprocess Eng 18: 267-279
14. Gelmi C, Pérez-Correa R, González M, Agosin E (2000) Solid substrate cultivation of Gibberella fujikuroi on an inert support. Process Biochem 35:1227-1233
15. 3 production in solid-state fermentation. Process Biochem 37:1033-1040
16. Godbole SP, Schumpe A, Shah T, Carr NL (1984) Hydrodynamics and mass transfer in non-Newtonian solutions in a bubble column. AIChE J 30:213-220
17. Gouveia ER, Hokka CO, Badino-Jr AC (2003) The effects of geometry and operational conditions on gas holdup, liquid circulation and mass transfer in an airlift reactor. Braz J Chem Eng 20:363-374
18. Gravilescu M, Tudose RZ (1998) Hydrodynamics of non-Newtonian liquids in external-loop airlift bioreactor. Part I. Study of the gas holdup. Bioprocess Eng 18:17-26
19. Gravilescu M, Tudose RZ (1999) Modelling mixing parameters in concentric-tube airlift bioreactors. Part I. Mixing time. Bioprocess Eng 20:423-428
20. Halard B, Kawase Y, Moo-Young M (1989) Mass transfer in a pilot plant scale airlift column with non-Newtonian fluids. Ind Eng Chem Res 28:243-245
21. Heinrich M, Rehm HJ (1981) Growth of Fusarium moniliforme on n-alkanes: comparison of an immobilization method with conventional processes. Eur J Appl Microbiol Biotechnol 11:239
22. Jones A, Pharis RP (1987) Production of gibberellins and bikaverin by cells of Gibberella fujikuroi immobilized in carrageenan. J Ferment Technol 65:717-722
23. Kawase Y (1989) Liquid circulation in external-loop airlift bioreactors. Biotechnol Bioeng 35:540-546
24. Kumar PKP, Lonsane BK (1987) Gibberellic acid by solid state fermentation: consistent and improved yields. Biotechnol Bioeng 30:267-271
25. Kumar PKP, Lonsane BK (1988) Immobilized growing cells of Gibberella fujikuroi P-3 for production of gibberellic acid and pigment in batch and semi-continuous cultures. Appl Microbiol Biotechnol 28:537-542
26. Metz B, Kossen NWF, van Suijdam JC (1979) The rheology of mould suspensions. Adv Biochem Eng 11:103-156
27. McManamey WJ, Wase DAJ (1986) Relationship between the volumetric mass transfer coefficient and gas holdup in airlift fermentors. Biotechnol Bioeng 28:1446-1448
28. Moo-Young M, Halard B, Allen DG, Burrell R, Kawase Y (1987) Oxygen transfer to mycelial fermentation broths in an airlift fermentor. Biotechnol Bioeng 30:746-753
29. Nava Saucedo JE, Barbotin JN, Thomas D (1989) Continuous production of gibberellic acid in a fixed-bed reactor by immobilized mycelia of Gibberella fujikuroi in calcium alginate beads. Appl Microbiol Biotechnol 30:226-233
30. Prokop A, Janík P, Sobotka M, Krumphanzi V (1983) Hydrodynamics, mass transfer, and yeast culture performance of a column bioreactor with ejector. Biotechnol Bioeng 25: 114-1160
31. Quintero RR (1981) Ingeniería bioquímica, Teoría y aplicaciones. Ed. Alambra. México
32. Schügerl K, Lücke J, Oels U (1977) Bubble column bioreactors. Adv Biochem Eng 7:1-81
33. Shah YT, Kelkar BG, Godbole SP, Deckwer WD (1982) Design parameters estimations for bubble column reactors. AIChE J 28:353-379
34. Shukla R, Srivastava AK, Chand S (2003) Bioprocess strategies and recovery processes in gibberellic acid fermentation. Biotechnol Bioprocess Eng 8:269-278
35. Tobajas M, García-Calvo E (2000) Comparison of experimental methods for determination of the volumetric mass transfer coefficient in fermentation processes. Heat Mass Transfer 36: 201-207
36. Tudzynski B (1999) Biosynthesis of gibberellins in Gibberella fujikuroi: biomolecular aspects. Appl Microbiol Biotechnol 52:298-310