Escherichia coli lipopolysaccharides produce serotype-specific hypothermic response in biotelemetered rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 292, Issue 5, 2007, Pages

  Akarsu, Eyup S ^a   Mamuk, Soner ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Acute phase response; Antipyretic cytokines; Cyclooxygenase 1 selective inhibitors; Endotoxin; Fever

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1 INHIBITOR; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 10; INTERLEUKIN 18; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VALERYLSALICYLATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DRUG ACTIVITY; ESCHERICHIA COLI; INDUCED HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SEROTYPE; TELEMETRY; TEMPERATURE SENSITIVITY;

ANIMALS; CYCLOOXYGENASE INHIBITORS; ESCHERICHIA COLI; HYPOTHERMIA; INTERLEUKIN-10; INTERLEUKIN-18; LIPOPOLYSACCHARIDES; MALE; PYRAZOLES; RATS; RATS, WISTAR; SALICYLATES; TELEMETRY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34248170130     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00786.2006     Document Type: Article

References (31)

1. Akarsu ES, Mamuk S, Arat S. Variable antipyretic effect of SC-58236, a selective cyclooxygenase (COX)-2 inhibitor, in rats. Adv Exp Med Biol 525: 137-140, 2003.
2. Almeida MC, Steiner AA, Branco LGS, Romanovsky AA. Cold-seeking behavior as a thermoregulatory strategy in systemic inflammation. Eur J Neurosci 23: 3359-3367, 2006.
3. DeRijk RH, Van Kampen M, Van Rooijen N, Berkenbosch F. Hypothermia to endotoxin involves reduced thermogenesis, macrophage-dependent mechanisms, and prostaglandins. Am J Physiol Regul Integr Comp Physiol 266: R1-R8, 1994.
4. Dogan MD, Ataoglu H, Akarsu ES. Effects of different serotypes of Escherichia coli lipopolysaccharides on body temperature in rats. Life Sci 67: 2319-2329, 2000.
5. Dogan MD, Ataoglu H, Akarsu ES. Effects of selective cycylooxygenase enzyme inhibitors on lipopolysaccharide-induced dual thermoregulatory changes in rats. Brain Res Bull 57: 179-185, 2002.
6. Dogan MD, Ataoglu H, Akarsu ES. Characterization of the hypothermic component of LPS-induced dual thermoregulatory response in rats. Pharmacol Biochem Behav 72: 143-150, 2002.
7. Dredge K, Connor TJ, Kelly JP, Leonard BE. Differential effect of a single high dose of the tricyclic antidepressant imipramine on interkeukin-1β and tumor necrosis factor-α secretion following an in vivo lipopolysaccharide challenge in rats. Int J Immunopharmacol 21: 663-673, 1999.
8. Feldberg W, Saxena PN. Prostaglandins, endotoxin, and lipid A on body temperature in rats. J Physiol 249: 601-615, 1975.
9. Felies M, von Horsten S, Pabst R, Nave H. Neuropeptide Y stabilizes body temperature and prevents hypotension in endotoxaemic rats. J Physiol 561: 245-252, 2004.
10. Gatti S, Beck J, Fantuzzi G, Bartfai T, Dinarello CA. Effect of interleukin-18 on mouse core temperature. Am J Physiol Regul Integr Comp Physiol 282: R702-R709, 2002.
11. Hardy P, Bhattacharya M, Abran D, Peri KG, Asselin P, Varma DR, Chemtob S. Increases in retinovascular prostaglandin receptor functions by cyclooxygenase-1 and -2 inhibition. Invest Ophthalmol Vis Sci 39: 1888-1898, 1998.
12. Hare AS, Clarke G, Tolchard S. Bacterial lipopolysaccharide- induced changes in FOS protein expression in the rat brain: correlation with thermoregulatory changes and plasma corticosterone. J Neuroendocrinol 7: 791-799, 1995.
13. Hart BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 12: 123-137, 1988.
14. Hillyer LM, Woodward B. Interleukin-10 concentration determined by sandwich enzyme-linked immunosorbent assay is unrepresentative of bioactivity in murine blood. Am J Physiol Regul Integr Comp Physiol 285: R1514-R1519, 2003.
15. Kluger MJ. Fever: role of pyrogens and cryogens. Physiol Rev 71: 93-127, 1991.
16. Kozak W. Regulated decrease in body temperature. In: Fever: Basic Mechanisms and Management, edited by Mackowiak PA. Philadelphia: Lippincott-Raven, 1997.
17. Kushner I, Rzewnicki DL. The acute phase response. In: Fever: Basic Mechanisms and Management, edited by Mackowiak PA. Philadelphia: Lippincott-Raven, 1997.
18. Lang CH, Bagby GJ, Spitzer JJ. Glucose kinetics and body temperature after lethal and nonlethal dose of endotoxin. Am J Physiol Regul Integr Comp Physiol 248: R471-R478, 1985.
19. Ledeboer A, Binnekade R, Breve JJP, Bol JGJM, Tilders FJH, Van Dam AM. Site-specific modulation of LPS-induced fever and interleukin-1β expression in rats by interleukin-10. Am J Physiol Regul Integr Comp Physiol 282: R1762-R1772, 2002.
20. Leon LR. Hypothermia in systemic inflammation: Role of cytokines. Front Biosci 9: 1877-1888, 2004.
21. Lerouge L, Vanderleyden J. O-antigen structural variation: mechanisms and possible roles in animal/plant-microbe intercations. FEMS Microbiol Rev 26: 17-47, 2002.
22. Martin SM, Malkinson TJ, Veale WL, Pittman QJ. Fever in pregnant, parturient, and lactating rats. Am J Physiol Regul Integr Comp Physiol 268: R919-R923, 1995.
23. Raetz CRH, Whitfield C. Lipopolysaccharide endotoxins. Annu Rev Biochem 71: 635-700, 2002.
24. Romanovsky AA, Szekely M. Fever and hypothermia: two adaptive thermoregulatory responses to systemic inflammation. Med Hypotheses 50: 219-226, 1998.
25. Romanovsky AA, Shido O, Sakurada S, Sugimoto N, Nagasaka T. Endotoxin shock: thermoregulatory mechanisms. Am J Physiol Regul Integr Comp Physiol 270: R693-R703, 1996.
26. Schotanus K, Holtkamp GM, Van Rooijen N, Tilders FJH, Berkenbosch F. Circulating tumor necrosis factor-α does not mediate endotoxin-induced hypothermia in rats. Am J Physiol Regul Integr Comp Physiol 268: R989-R996, 1995.
27. Smith CJ, Zhang Y, Koboldt CM, Muhammad J, Zweifel BS, Shaffer A, Talley JJ, Masferrer JL, Seibert K, Isacson PC. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci USA 95: 13313-13318, 1998.
28. Tegeder I, Pfeilschifter J, Geisslinger G. Cyclooxygenase- independent actions of cyclooxygenase inhibitors. FASEB J 15: 2057-2072, 2001.
29. Tolchard S, Hare AS, Nutt DJ, Clarke G. TNF-α mimics the endocrine but not the thermoregulatory responses of bacterial lipopolysaccharide (LPS): Correlation with FOS-expression in the brain. Neuropharmacology 35: 243-248, 1996.
30. Yang WW, Krukoff TL. Nitric oxide regulates body temperature, neuronal activation and interleukin-1β gene expression in the hypothalamic paraventricular nucleus to immune stress. Neuropharmacology 39: 2075-2089, 2000.
31. Zhang YH, Lu J, Elmquist JK, Saper CB. Specific roles of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide-induced fever and Fos expression in rat brain. J Comp Neurol 463: 3-12, 2003.