Serotonin syndrome associated with the use of escitalopram

CNS Spectrums

Volumn 12, Issue 4, 2007, Pages 270-274

  Huska, Matthew T ^a   Catalano, Glenn ^a,b,c   Catalano, Maria C ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCITALOPRAM;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; FEMALE; HUMAN; INTENSIVE CARE UNIT; LABORATORY TEST; MENTAL HEALTH; POLYPHARMACY; PRIORITY JOURNAL; SEROTONIN SYNDROME;

EID: 34248167693     PISSN: 10928529     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1092852900021027     Document Type: Article

References (37)

1. Burke WJ, Gergel I, Bose A. Fixed-dosed trial of the single isomer SSRI escitalopram in depressed outpatients. J Clin Psychiatry. 2002;63:331-336.
2. Physicians' Desk Reference. 60th ed. Montvale, NJ: Medical Economics Company; 2006.
3. Siadock BJ, Sadock VA. Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry. 9th ed. Philadelphia, Penn: Lippincott Williams & Wilkins; 2003.
4. Mosby's Drug Consult 15th ed. St. Louis, MO: Mosby, Inc.; 2005.
5. Nirmalani A, Stock SL, Catalano G. Syndrome of inappropriate antidiuretic hormone associated with escitalopram therapy. CNS Spectr. 2006;11:429-432.
6. Zelefsky JR, Fine HF, Rubenstein VJ, Hsu IS, Finger FT. Escitalopram-induced uveal effusions and bilateral angle closure glaucoma. Am J Ophthalmol. 2006;141:1144-1147.
7. Ozalp E, Soygur H, Cankurtaran ES, et al. Sertraline, escitalopram and tianeptine related abnormal movements but not with bupropion: a case report. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30:1337-1339.
8. Saper CB. Brain stem modulation of sensation, movement, and consciousness. In: Kandel ER, Schwartz JH, Jessell TM, eds. Principles of Neural Science. 4th ed. New York, NY: McGraw-Hill; 2000:889-909.
9. Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med. 2005;352:1112-1120.
10. Isbister GK. Comment: serotonin syndrome, mydriasis, and cyproheptadine. Ann Pharmacother. 2001;35:1672-1673.
11. Isbister GK, Whyte IM. Serotonin toxicity and malignant hyperthermia: role of 5-HT2 receptors. Br J Anaesth. 2002;88:603-604.
12. Nisijima K, Shioda K, Yoshino T, Takano K, Kato S. Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. Pharmacopsychiatry. 2004;37:57-62.
13. Nisijima K, Yoshino T, Yui K, Katoh S. Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome. Brain Res. 2001;890:23-31.
14. Van Oekelen O, Megens A, Meert T, Luyten WH, Leysen JE. Functional study of rat 5-HT2A receptors using antisense oligonucleotides. J Neurochem. 2003;85:1087-1100.
15. Demirkiran M, Jankivic J, Dean JM. Ecstasy intoxication: an overlap between serotonin syndrome and neuroleptic malignant syndrome. Clin Neuropharmacol. 1996;19:157-164.
16. Done CJ, Sharp T. Biochemical evidence for the regulation of central noradrenergic activity by 5-HT1A and 5-HT2 receptors: microdialysis studies in the awake and anaesthetized rat. Neuropharmacology. 1994;33:411-421.
17. Fink M. Toxic serotonin syndrome or neuroleptic malignant syndrome? Pharmacopsychiatry. 1996;29:159-161.
18. Kline SS, Mauro LS, Scala-Barnett DM, Zick D. Serotonin syndrome versus neuroleptic malignant syndrome as a cause of death. Clin Pharm. 1989;8:510-514.
19. Nisijima K, Shioda K, Yoshino T, Takano K, Kato S. Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome. Neurochem Int. 2003;43:155-164.
20. Mann SC, Caroff SN, Keck PE, Lazarus A. Neuroleptic Malignant Syndrome and Related Conditions. 2nd ed. Washington, DC: American Psychiatric Publishing, Inc; 2003.
21. Sternbach H. The serotonin syndrome. Am J Psychiatry. 1991;148:705-713.
22. Birmes P, Coppin D, Schmitt L, et al. Serotonin syndrome: a brief review. CMAJ. 2003;168:1439-1442.
23. Smith B, Prochop DJ. Central-nervous-system effects of ingestin of L-tryptophan by normal subjects. N Engl J Med. 1962;267:1338-1341.
24. Curzon G, Ettlinger G, Cole M, et al. The biochemical, behavioral and neurologic effects of high L-tryptophan intake in the rhesus monkey. Neurology. 1963;12:431-438.
25. Oates JA, Sjoerdsma A. Neurologic effects of tryptophan in patients receiving a monoamine oxidase inhibitor. Neurology. 1960;10:1076-1078.
26. Beaumont G. Drug interactions with clomipramine (Anafranil). J Int Med Res. 1973;1:480-484.
27. White K, Simpson G. Combined MAOI-tricyclic antidepressant treatment: a reevaluation. J Clin Psychopharmacol. 1981;1:264-281.
28. Kinzie E, Meltzer-Brody S. Possible serotonin syndrome with citalopram following cross-titration of clozapine to ziprasidone. Gen Hosp Psychiatry. 2005;27:223-224.
29. Marlowe K, Schirgel D. Quetiapine and citalopram: aetiological significance in serotonin syndrome. N Z Med J. 2006;119:1237.
30. Bernard L, Stern R, Lew D, Hoffmeyer P. Serotonin syndrome after concomitant treatment with linezolid and citalopram. Clin Infect Dis. 2003;36:1197.
31. Debellis RJ, Schaefer OP, Liquori M, Volturo GA. Linezolid associated serotonin syndrome after concomitant treatment with citalopram and mirtazepine in a critically ill bone marrow transplant recipient. J Intensive Care Med. 2005;20:351-353.
32. Tahir N. Serotonin syndrome as a consequence of drug-resistant infections: an interaction between linezolid and citalopram. J Am Med Dir Assoc. 2004;5:111-113.
33. Dams R, Benjits TH, Lambert WE, et al. A fatal case of serotonin syndrome after combined moclobemide-citalopram intoxication. J Anal Toxicol. 2001;25:147-151.
34. Isbister GK, McGettigan P, Dawson A. A fatal case of moclobemide- citalopram intoxication. J Anal Toxicol. 2001;25:716-717.
35. Voirol P, Hodel PF, Zullino D, Baumann P. Serotonin syndrome after small doses of citalopram or sertraline. J Clin Psychopharmacol. 2000;20:713-714.
36. Mahlberg R, Kunz D, Sasse J, Kirchheiner J. Serotonin syndrome with tramadol and citalopram. Am J Psychiatry. 2004;161:1129.
37. Gillman PK. The serotonin syndrome and its treatment. J Psychopharmacol. 1999;13:100-109.