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Volumn 7, Issue SUPPL., 2007, Pages

Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations

Author keywords

Coenzyme Q10; Coenzyme Q10 bioavailability; Plasma coenzyme Q10 concentration; Solubilized coenzyme Q10 formulations; Ubiquinol; Ubiquinone

Indexed keywords

PLACEBO; UBIDECARENONE;

EID: 34248162014     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2007.03.003     Document Type: Review
Times cited : (198)

References (60)
  • 1
    • 0036525567 scopus 로고    scopus 로고
    • Coenzyme Q10 as a possible treatment for neurodegenerative diseases
    • Beal M.F. Coenzyme Q10 as a possible treatment for neurodegenerative diseases. Free Rad. Res. 36 (2002) 455-460
    • (2002) Free Rad. Res. , vol.36 , pp. 455-460
    • Beal, M.F.1
  • 3
    • 18744375715 scopus 로고    scopus 로고
    • Potential role of ubiquinone (coenzyme Q10) in pediatric cardiomyopathy
    • Bhagavan H.N., and Chopra R.K. Potential role of ubiquinone (coenzyme Q10) in pediatric cardiomyopathy. Clin. Nutr. 24 (2005) 331-338
    • (2005) Clin. Nutr. , vol.24 , pp. 331-338
    • Bhagavan, H.N.1    Chopra, R.K.2
  • 4
    • 33645099245 scopus 로고    scopus 로고
    • Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics
    • Bhagavan H.N., and Chopra R.K. Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic. Res. 40 (2006) 445-453
    • (2006) Free Radic. Res. , vol.40 , pp. 445-453
    • Bhagavan, H.N.1    Chopra, R.K.2
  • 5
    • 33745627386 scopus 로고    scopus 로고
    • Absorption and bioavailability of coenzyme Q10
    • Ebadi M., Marwah J., and Chopra R. (Eds), Prominent Press, Scottsdale
    • Bhagavan H.N., Chopra R.K., and Sinatra S.T. Absorption and bioavailability of coenzyme Q10. In: Ebadi M., Marwah J., and Chopra R. (Eds). Coenzyme Q10 in mitochondrial disease vol. 1 (2001), Prominent Press, Scottsdale 143-147
    • (2001) Coenzyme Q10 in mitochondrial disease , vol.1 , pp. 143-147
    • Bhagavan, H.N.1    Chopra, R.K.2    Sinatra, S.T.3
  • 7
    • 34248167384 scopus 로고    scopus 로고
    • Antioxidant nutrient interactions in human subjects
    • Chopra R.K., and Bhagavan H.N. Antioxidant nutrient interactions in human subjects. J. Am. Coll. Nutr. 18 (1999) 544
    • (1999) J. Am. Coll. Nutr. , vol.18 , pp. 544
    • Chopra, R.K.1    Bhagavan, H.N.2
  • 9
    • 33645103688 scopus 로고    scopus 로고
    • Assessment of coenzyme Q10 bioavailability using a coupled in vitro digestion/Caco-2 human intestinal cell model
    • Craft N.E., Tucker R.T., Chitchumroonchokchai C., Failla M., and Bhagavan H.N. Assessment of coenzyme Q10 bioavailability using a coupled in vitro digestion/Caco-2 human intestinal cell model. FASEB J. 19 (2005) A449
    • (2005) FASEB J. , vol.19
    • Craft, N.E.1    Tucker, R.T.2    Chitchumroonchokchai, C.3    Failla, M.4    Bhagavan, H.N.5
  • 10
    • 0035667921 scopus 로고    scopus 로고
    • Biochemical functions of coenzyme Q10
    • Crane F.L. Biochemical functions of coenzyme Q10. J. Am. Coll. Nutr. 20 (2001) 591-598
    • (2001) J. Am. Coll. Nutr. , vol.20 , pp. 591-598
    • Crane, F.L.1
  • 11
    • 33748089976 scopus 로고    scopus 로고
    • Approaches to the treatment of mitochondrial diseases
    • DiMauro S., Hirano M., and Schon E.A. Approaches to the treatment of mitochondrial diseases. Muscle Nerve 34 (2006) 265-283
    • (2006) Muscle Nerve , vol.34 , pp. 265-283
    • DiMauro, S.1    Hirano, M.2    Schon, E.A.3
  • 12
    • 0037341210 scopus 로고    scopus 로고
    • Potential usefulness of coenzyme Q10 in the treatment of idiopathic dilated cardiomyopathy in children
    • Elshershari H., Ozer S., Ozkutlu S., and Ozme S. Potential usefulness of coenzyme Q10 in the treatment of idiopathic dilated cardiomyopathy in children. Int. J. Cardiol. 88 (2003) 101-102
    • (2003) Int. J. Cardiol. , vol.88 , pp. 101-102
    • Elshershari, H.1    Ozer, S.2    Ozkutlu, S.3    Ozme, S.4
  • 13
    • 0029042393 scopus 로고
    • Biochemical, physiological and medical aspects of ubiquinone function
    • Ernster L., and Dallner G. Biochemical, physiological and medical aspects of ubiquinone function. Biochim. Biophys. Acta 1271 (1995) 195-204
    • (1995) Biochim. Biophys. Acta , vol.1271 , pp. 195-204
    • Ernster, L.1    Dallner, G.2
  • 15
    • 0025195880 scopus 로고
    • Co-enzyme Q10: A new drug for cardiovascular disease
    • Greenberg S., and Frishman W.H. Co-enzyme Q10: A new drug for cardiovascular disease. J. Clin. Pharmacol. 30 (1990) 596-608
    • (1990) J. Clin. Pharmacol. , vol.30 , pp. 596-608
    • Greenberg, S.1    Frishman, W.H.2
  • 17
    • 33645854921 scopus 로고    scopus 로고
    • Safety assessment of coenzyme Q10 (Kaneka Q10) in healthy subjects: a double-blind, randomized, placebo-controlled trial
    • Ikematsu H., Nakamura K., Harashima S., Fujii K., and Fukutomi N. Safety assessment of coenzyme Q10 (Kaneka Q10) in healthy subjects: a double-blind, randomized, placebo-controlled trial. Regul. Toxicol. Pharmacol. 44 (2006) 212-218
    • (2006) Regul. Toxicol. Pharmacol. , vol.44 , pp. 212-218
    • Ikematsu, H.1    Nakamura, K.2    Harashima, S.3    Fujii, K.4    Fukutomi, N.5
  • 18
    • 0032757898 scopus 로고    scopus 로고
    • Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well-being in patients with Type 1 diabetes mellitus
    • Henriksen J.E., Andersen C.B., Hother-Nielsen O., Vaag A., Mortensen S.A., and Beck-Nielsen H. Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well-being in patients with Type 1 diabetes mellitus. Diabet. Med. 16 (1999) 312-318
    • (1999) Diabet. Med. , vol.16 , pp. 312-318
    • Henriksen, J.E.1    Andersen, C.B.2    Hother-Nielsen, O.3    Vaag, A.4    Mortensen, S.A.5    Beck-Nielsen, H.6
  • 19
    • 0029257854 scopus 로고
    • Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. The Q10 Study Group
    • Hofman-Bang C., Rehnqvist N., Swedberg K., Wiklund I., and Astrom H. Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. The Q10 Study Group. J. Card. Fail. 1 (1995) 101-107
    • (1995) J. Card. Fail. , vol.1 , pp. 101-107
    • Hofman-Bang, C.1    Rehnqvist, N.2    Swedberg, K.3    Wiklund, I.4    Astrom, H.5
  • 20
    • 33751106205 scopus 로고    scopus 로고
    • Study on safety and bioavailability of ubiquinol (Kaneka QH™) after single and 4-week multiple oral administration to healthy volunteers
    • Hosoe K., Kitano M., Kishida H., Kubo H., Fujii K., and Kitahaara M. Study on safety and bioavailability of ubiquinol (Kaneka QH™) after single and 4-week multiple oral administration to healthy volunteers. Regul. Toxicol. Phamacol. 47 (2007) 19-28
    • (2007) Regul. Toxicol. Phamacol. , vol.47 , pp. 19-28
    • Hosoe, K.1    Kitano, M.2    Kishida, H.3    Kubo, H.4    Fujii, K.5    Kitahaara, M.6
  • 21
    • 0030901230 scopus 로고    scopus 로고
    • Effect of oral coenzyme Q10 supplementation on the oxidation resistance of human VLDL+LDL fraction: absorption and antioxidative properties of oil and granule-based preparations
    • Kaikkonen J., Nyyssonen K., Porkkala-Sarataho E., Poulsen H.E., Metsa-Ketela T., Hayn M., Salonen R., and Salonen J.T. Effect of oral coenzyme Q10 supplementation on the oxidation resistance of human VLDL+LDL fraction: absorption and antioxidative properties of oil and granule-based preparations. Free Radic. Biol. Med. 22 (1997) 1195-1202
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 1195-1202
    • Kaikkonen, J.1    Nyyssonen, K.2    Porkkala-Sarataho, E.3    Poulsen, H.E.4    Metsa-Ketela, T.5    Hayn, M.6    Salonen, R.7    Salonen, J.T.8
  • 23
    • 0033828630 scopus 로고    scopus 로고
    • Antioxidative efficacy of parallel and combined supplementation with coenzyme Q10 and d-alpha-tocopherol in mildly hypercholesterolemic subjects: a randomized placebo-controlled clinical study
    • Kaikkonen J., Nyyssonen K., Tomasi A., Iannone A., Tuomainen T.-P., Porkkala-Sarataho E., and Salonen J.T. Antioxidative efficacy of parallel and combined supplementation with coenzyme Q10 and d-alpha-tocopherol in mildly hypercholesterolemic subjects: a randomized placebo-controlled clinical study. Free Radic. Res. 33 (2000) 329-340
    • (2000) Free Radic. Res. , vol.33 , pp. 329-340
    • Kaikkonen, J.1    Nyyssonen, K.2    Tomasi, A.3    Iannone, A.4    Tuomainen, T.-P.5    Porkkala-Sarataho, E.6    Salonen, J.T.7
  • 24
    • 0036554573 scopus 로고    scopus 로고
    • Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels
    • Kaikkonen J., Tuomainen T.-P., Nyyssonen K., and Salonen J.T. Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels. Free Radic. Res. 36 (2002) 389-397
    • (2002) Free Radic. Res. , vol.36 , pp. 389-397
    • Kaikkonen, J.1    Tuomainen, T.-P.2    Nyyssonen, K.3    Salonen, J.T.4
  • 26
    • 85009226418 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease
    • The Huntington Study Group
    • Kieburtz K., and The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 57 (2001) 397-404
    • (2001) Neurology , vol.57 , pp. 397-404
    • Kieburtz, K.1
  • 27
    • 0032470151 scopus 로고    scopus 로고
    • Coenzyme Q10 in cardiovascular disease with special emphasis on heart failure and myocardial, ischemia
    • Langsjoen P.H., and Langsjoen A.M. Coenzyme Q10 in cardiovascular disease with special emphasis on heart failure and myocardial, ischemia. Asia Pacific Heart J. 7 (1998) 160-168
    • (1998) Asia Pacific Heart J. , vol.7 , pp. 160-168
    • Langsjoen, P.H.1    Langsjoen, A.M.2
  • 28
    • 0032588768 scopus 로고    scopus 로고
    • Overview of the use of coenzyme Q10 in cardiovascular disease
    • Langsjoen P.H., and Langsjoen A.M. Overview of the use of coenzyme Q10 in cardiovascular disease. Biofactors 9 (1999) 273-284
    • (1999) Biofactors , vol.9 , pp. 273-284
    • Langsjoen, P.H.1    Langsjoen, A.M.2
  • 31
    • 0038044626 scopus 로고    scopus 로고
    • Total coenzyme Q10 concentrations in Asian men following multiple oral 50-mg doses administered as coenzyme Q10 sustained release tablets or regular tablets
    • Lu W.-L., Zhang Q., Lee H.-S., Zhou T.-Y., Sun H.-D., Zhang D.-W., Zheng L., Lee M., and Wong S.-M. Total coenzyme Q10 concentrations in Asian men following multiple oral 50-mg doses administered as coenzyme Q10 sustained release tablets or regular tablets. Biol. Pharm. Bull. 26 (2003) 52-55
    • (2003) Biol. Pharm. Bull. , vol.26 , pp. 52-55
    • Lu, W.-L.1    Zhang, Q.2    Lee, H.-S.3    Zhou, T.-Y.4    Sun, H.-D.5    Zhang, D.-W.6    Zheng, L.7    Lee, M.8    Wong, S.-M.9
  • 32
    • 0000546809 scopus 로고
    • Pharmacokinetics of coenzyme ubidecarenone in healthy volunteers
    • Folkers K., and Yamamura Y. (Eds), Elsevier, Amsterdam
    • Lucker P.W., Wetzelsberger N., Hennings G., and Rehn D. Pharmacokinetics of coenzyme ubidecarenone in healthy volunteers. In: Folkers K., and Yamamura Y. (Eds). Biomedical and Clinical Aspects of Coenzyme Q vol. 4 (1984), Elsevier, Amsterdam 141-151
    • (1984) Biomedical and Clinical Aspects of Coenzyme Q , vol.4 , pp. 141-151
    • Lucker, P.W.1    Wetzelsberger, N.2    Hennings, G.3    Rehn, D.4
  • 33
    • 0036329365 scopus 로고    scopus 로고
    • Bioequivalence of coenzyme Q10 from over-the-counter supplements
    • Miles M.V., Horn P., Miles L., Tang P., Steele P., and DeGrauw T. Bioequivalence of coenzyme Q10 from over-the-counter supplements. Nutr. Res. 22 (2002) 919-929
    • (2002) Nutr. Res. , vol.22 , pp. 919-929
    • Miles, M.V.1    Horn, P.2    Miles, L.3    Tang, P.4    Steele, P.5    DeGrauw, T.6
  • 34
    • 0038324376 scopus 로고    scopus 로고
    • Plasma coenzyme Q10 reference intervals, but not redox status, are affected by gender and race in self-reported healthy adults
    • Miles M.V., Horn P.S., Morrison J.A., Tang P.H., DeGrauw T., and Pesce A.J. Plasma coenzyme Q10 reference intervals, but not redox status, are affected by gender and race in self-reported healthy adults. Clin. Chim. Acta 332 (2003) 123-132
    • (2003) Clin. Chim. Acta , vol.332 , pp. 123-132
    • Miles, M.V.1    Horn, P.S.2    Morrison, J.A.3    Tang, P.H.4    DeGrauw, T.5    Pesce, A.J.6
  • 37
    • 0026734786 scopus 로고
    • Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation
    • Mohr D., Bowry V.W., and Stocker R. Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim. Biophys. Acta 1126 (1992) 247-254
    • (1992) Biochim. Biophys. Acta , vol.1126 , pp. 247-254
    • Mohr, D.1    Bowry, V.W.2    Stocker, R.3
  • 38
    • 0032770261 scopus 로고    scopus 로고
    • Antioxidant defenses in rat intestine and mesenteric lymph
    • Mohr D., Umeda Y., Redgrave T.G., and Stocker R. Antioxidant defenses in rat intestine and mesenteric lymph. Redox Rep. 4 (1999) 79-87
    • (1999) Redox Rep. , vol.4 , pp. 79-87
    • Mohr, D.1    Umeda, Y.2    Redgrave, T.G.3    Stocker, R.4
  • 39
    • 27244460578 scopus 로고    scopus 로고
    • The bioavailability of coenzyme Q10 supplements available in New Zealand differs markedly
    • Molyneux S., Florkowski C., Lever M., and George P. The bioavailability of coenzyme Q10 supplements available in New Zealand differs markedly. N.Z. Med. J. 117 (2004) U1108
    • (2004) N.Z. Med. J. , vol.117
    • Molyneux, S.1    Florkowski, C.2    Lever, M.3    George, P.4
  • 41
    • 0026497194 scopus 로고
    • Ubiquinone (coenzyme Q10) in the long-term treatment of idiopathic dilated cardiomyopathy
    • Permanetter B., Rossy W., Klein G., Weingartner F., Seidl K.F., and Blomer H. Ubiquinone (coenzyme Q10) in the long-term treatment of idiopathic dilated cardiomyopathy. Eur. Heart J. 13 (1992) 1528-1533
    • (1992) Eur. Heart J. , vol.13 , pp. 1528-1533
    • Permanetter, B.1    Rossy, W.2    Klein, G.3    Weingartner, F.4    Seidl, K.F.5    Blomer, H.6
  • 44
    • 0141761467 scopus 로고    scopus 로고
    • Coenzyme Q10 in neurodegenerative diseases
    • Shults C.W. Coenzyme Q10 in neurodegenerative diseases. Curr. Med. Chem. 10 (2003) 1917-1921
    • (2003) Curr. Med. Chem. , vol.10 , pp. 1917-1921
    • Shults, C.W.1
  • 45
    • 3042717908 scopus 로고    scopus 로고
    • Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease
    • Shults C.W., Beal M.F., Song D., and Fontaine D. Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease. Exp. Neurol. 188 (2004) 491-494
    • (2004) Exp. Neurol. , vol.188 , pp. 491-494
    • Shults, C.W.1    Beal, M.F.2    Song, D.3    Fontaine, D.4
  • 47
    • 0345451597 scopus 로고    scopus 로고
    • Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients
    • Shults C.W., Beal M.F., Fontaine D., Nakano K., and Haas R.H. Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients. Neurology 50 (1998) 793-795
    • (1998) Neurology , vol.50 , pp. 793-795
    • Shults, C.W.1    Beal, M.F.2    Fontaine, D.3    Nakano, K.4    Haas, R.H.5
  • 48
    • 33746076342 scopus 로고    scopus 로고
    • Effect on absorption and oxidative stress of different oral Coenzyme Q10 dosages and intake strategy in healthy men
    • Singh R.B., Niaz M.A., Kumar A., Sindberg C.D., Moesgaard S., and Littarru G.P. Effect on absorption and oxidative stress of different oral Coenzyme Q10 dosages and intake strategy in healthy men. Biofactors 25 (2005) 219-224
    • (2005) Biofactors , vol.25 , pp. 219-224
    • Singh, R.B.1    Niaz, M.A.2    Kumar, A.3    Sindberg, C.D.4    Moesgaard, S.5    Littarru, G.P.6
  • 49
    • 4043181369 scopus 로고    scopus 로고
    • Clinical laboratory monitoring of coenzyme Q10 use in neurologic and muscular diseases
    • Steele P.E., Tang P.H., DeGrauw A.J., and Miles M.V. Clinical laboratory monitoring of coenzyme Q10 use in neurologic and muscular diseases. Am. J. Clin. Pathol. 121 (2004) S113-S120
    • (2004) Am. J. Clin. Pathol. , vol.121
    • Steele, P.E.1    Tang, P.H.2    DeGrauw, A.J.3    Miles, M.V.4
  • 50
    • 0035134146 scopus 로고    scopus 로고
    • HPLC analysis reduced and oxidized coenzyme Q(10) in human plasma
    • Tang P.H., Miles M.V., DeGrauw A., Hershey A., and Pesce A. HPLC analysis reduced and oxidized coenzyme Q(10) in human plasma. Clin. Chem. 47 (2001) 256-265
    • (2001) Clin. Chem. , vol.47 , pp. 256-265
    • Tang, P.H.1    Miles, M.V.2    DeGrauw, A.3    Hershey, A.4    Pesce, A.5
  • 52
    • 0033133426 scopus 로고    scopus 로고
    • Lack of effect of coenzyme Q on left ventricular function in patients with congestive heart failure
    • Watson P.S., Scalia G.M., Galbraith A., Burstow D.J., Bett N., and Aroney C.N. Lack of effect of coenzyme Q on left ventricular function in patients with congestive heart failure. J. Am. Coll. Cardiol. 33 (1999) 1549-1552
    • (1999) J. Am. Coll. Cardiol. , vol.33 , pp. 1549-1552
    • Watson, P.S.1    Scalia, G.M.2    Galbraith, A.3    Burstow, D.J.4    Bett, N.5    Aroney, C.N.6
  • 53
    • 0030941494 scopus 로고    scopus 로고
    • Intestinal absorption of coenzyme Q10 administered in a meal or as capsules to healthy subjects
    • Weber C., Bysted A., and Holmer G. Intestinal absorption of coenzyme Q10 administered in a meal or as capsules to healthy subjects. Nutr. Res. 17 (1997) 941-945
    • (1997) Nutr. Res. , vol.17 , pp. 941-945
    • Weber, C.1    Bysted, A.2    Holmer, G.3
  • 54
    • 0030610695 scopus 로고    scopus 로고
    • The coenzyme Q10 content of the average Danish diet
    • Weber C., Bysted A., and Holmer G. The coenzyme Q10 content of the average Danish diet. Int. J. Vitam. Nutr. Res. 67 (1997) 123-129
    • (1997) Int. J. Vitam. Nutr. Res. , vol.67 , pp. 123-129
    • Weber, C.1    Bysted, A.2    Holmer, G.3
  • 57
    • 0031571131 scopus 로고    scopus 로고
    • Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress
    • Yamashita S., and Yamamoto Y. Simultaneous detection of ubiquinol and ubiquinone in human plasma as a marker of oxidative stress. Anal. Biochem. 250 (1997) 66-73
    • (1997) Anal. Biochem. , vol.250 , pp. 66-73
    • Yamashita, S.1    Yamamoto, Y.2
  • 59
  • 60
    • 0346788999 scopus 로고    scopus 로고
    • Serum coenzyme Q10 concentrations in healthy men supplemented with 30 mg or 100 mg coenzyme Q10 for two months in a randomised controlled study
    • Zita C., Overvad K., Mortensen S.A., Sindberg C.D., Moesgaard S., and Hunter D.A. Serum coenzyme Q10 concentrations in healthy men supplemented with 30 mg or 100 mg coenzyme Q10 for two months in a randomised controlled study. Biofactors 18 (2003) 185-193
    • (2003) Biofactors , vol.18 , pp. 185-193
    • Zita, C.1    Overvad, K.2    Mortensen, S.A.3    Sindberg, C.D.4    Moesgaard, S.5    Hunter, D.A.6


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