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Volumn 42, Issue 4, 2007, Pages 233-244

Continuous erythropoiesis receptor activator (CERA): An erythropoiesis-stimulating agent for the treatment of anemia in patients with chronic kidney disease

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL; CISPLATIN; CONTINUOUS ERYTHROPOIESIS RECEPTOR ACTIVATOR; HEMOGLOBIN; LEVODOPA; METFORMIN; METHOTREXATE; METHYLDOPA; MIRCEVA; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PHENYTOIN; PLACEBO; PROCAINAMIDE; PROTON PUMP INHIBITOR; RECOMBINANT ERYTHROPOIETIN; SULFONAMIDE; TRIMETHOPRIM; UNCLASSIFIED DRUG;

EID: 34248162009     PISSN: 1082801X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (41)
  • 1
    • 34248141986 scopus 로고    scopus 로고
    • National Kidney Foundation web site. Available at:, Accessed March 15, 2007
    • National Kidney Foundation web site. Available at: http://www.kidney.org. Accessed March 15, 2007.
  • 3
    • 0034816679 scopus 로고    scopus 로고
    • Anemia: An early complication of chronic renal insufficiency
    • Kazmi WH, Kausz AT, Khan S, et al. Anemia: An early complication of chronic renal insufficiency. Am J Kid Dis. 2001;38:803-812.
    • (2001) Am J Kid Dis , vol.38 , pp. 803-812
    • Kazmi, W.H.1    Kausz, A.T.2    Khan, S.3
  • 4
    • 0036154114 scopus 로고    scopus 로고
    • Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: Results from the Third National Health and Nutrition Examination Survey
    • Hsu C-Y, McCulloch CE, Curhan GC. Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: Results from the Third National Health and Nutrition Examination Survey. J Am Soc Nephrol. 2002;13:504-510.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 504-510
    • Hsu, C.-Y.1    McCulloch, C.E.2    Curhan, G.C.3
  • 5
    • 34248165783 scopus 로고    scopus 로고
    • Opportunities to optimize anemia management among chronic kidney disease patients - results from the STRIDE registry [abstract]
    • Abstract SU-PO836
    • Kausz AT, Kliger A, Port FK, et al. Opportunities to optimize anemia management among chronic kidney disease patients - results from the STRIDE registry [abstract]. J Am Soc Nephrol. 2002;13:640A. Abstract SU-PO836.
    • (2002) J Am Soc Nephrol , vol.13
    • Kausz, A.T.1    Kliger, A.2    Port, F.K.3
  • 6
    • 12244284657 scopus 로고    scopus 로고
    • Silverberg DS.Wexler D, Blum M, et al. The effect of correction of anaemia in diabetics and non-diabetics with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron. Nephrol Dial Transplant. 2003;18:141-146.
    • Silverberg DS.Wexler D, Blum M, et al. The effect of correction of anaemia in diabetics and non-diabetics with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron. Nephrol Dial Transplant. 2003;18:141-146.
  • 7
    • 0036177366 scopus 로고    scopus 로고
    • Effects of exercise training plus normalization of hematocrit on exercise capacity and health-related quality of life
    • Painter P, Moore G, Carlson L, et al. Effects of exercise training plus normalization of hematocrit on exercise capacity and health-related quality of life. Am J Kidney Dis. 2002;39:257-265.
    • (2002) Am J Kidney Dis , vol.39 , pp. 257-265
    • Painter, P.1    Moore, G.2    Carlson, L.3
  • 9
    • 3042772186 scopus 로고    scopus 로고
    • Anemia management and outcomes from 12 countries in the Dialysis Outcomes and Practice Patterns Study (DOPPS)
    • Pisoni RL, Bragg-Gresham JL, Young EW, et al. Anemia management and outcomes from 12 countries in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2004;44:94-111.
    • (2004) Am J Kidney Dis , vol.44 , pp. 94-111
    • Pisoni, R.L.1    Bragg-Gresham, J.L.2    Young, E.W.3
  • 10
    • 33646345152 scopus 로고    scopus 로고
    • National Kidney Foundation. KDOQI clinical practice guidelines and clinical practice recommendations for anemia in chronic kidney disease
    • KDOQI;
    • KDOQI; National Kidney Foundation. KDOQI clinical practice guidelines and clinical practice recommendations for anemia in chronic kidney disease. Am J Kidney Dis. 2006;47(5 suppl 3):S11-145.
    • (2006) Am J Kidney Dis , vol.47 , Issue.5 SUPPL. 3
  • 11
    • 33750983605 scopus 로고    scopus 로고
    • CHOIR Investigators. Correction of anemia with epoetin alfa in chronic kidney disease
    • Singh AK, Szczech L, Tang, et al; CHOIR Investigators. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med. 2006;355:2085-2098.
    • (2006) N Engl J Med , vol.355 , pp. 2085-2098
    • Singh, A.K.1    Szczech, L.2    Tang3
  • 12
    • 33751002326 scopus 로고    scopus 로고
    • CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia
    • Drueke TB, Locatelli F, Clyne N, et al; CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med. 2006;355:2071-2084.
    • (2006) N Engl J Med , vol.355 , pp. 2071-2084
    • Drueke, T.B.1    Locatelli, F.2    Clyne, N.3
  • 13
    • 34248211482 scopus 로고    scopus 로고
    • Epogen [package insert, Thousand Oaks, Calif: Amgen; 2007
    • Epogen [package insert]. Thousand Oaks, Calif: Amgen; 2007.
  • 14
    • 34248181777 scopus 로고    scopus 로고
    • Procrit [package insert, Raritan, NJ: Ortho Biotech; 2007
    • Procrit [package insert]. Raritan, NJ: Ortho Biotech; 2007.
  • 15
    • 34248204376 scopus 로고    scopus 로고
    • Aranesp [package insert, Thousand Oaks, Calif: Amgen; 2007
    • Aranesp [package insert]. Thousand Oaks, Calif: Amgen; 2007.
  • 16
    • 33644875091 scopus 로고    scopus 로고
    • (continuous erythropoietin receptor activator): A new erythropoiesis-stimulating agent for the treatment of anemia
    • Macdougall IC. CERA (continuous erythropoietin receptor activator): A new erythropoiesis-stimulating agent for the treatment of anemia. Curr Hematol Rep. 2005;4:436-440.
    • (2005) Curr Hematol Rep , vol.4 , pp. 436-440
    • Macdougall, I.C.1
  • 17
    • 34248218368 scopus 로고    scopus 로고
    • Consistent pharmacokinetic properties of CERA (continuous erythropoietin receptor activator) in healthy volunteers and in patients with CKD. Poster
    • presented at: April 19-23, Chicago,Ill
    • Macdougall IC, Reigner B, Dougherty FC. Consistent pharmacokinetic properties of CERA (continuous erythropoietin receptor activator) in healthy volunteers and in patients with CKD. Poster presented at: National Kidney Foundation Spring 2006 Clinical Meeting; April 19-23, 2006; Chicago,Ill.
    • (2006) National Kidney Foundation Spring 2006 Clinical Meeting
    • Macdougall, I.C.1    Reigner, B.2    Dougherty, F.C.3
  • 18
    • 34248229992 scopus 로고    scopus 로고
    • CERA acts differently at the erythropoietin (EPO) receptor compared with epoetin beta: UT-7 and CD34+ cell stimulation assays. Poster
    • presented at: November 14-19, San Diego, Calif
    • Jarsch M, Kubbies M, Lanzendörfer M, Haselbeck A, Brandt M. CERA acts differently at the erythropoietin (EPO) receptor compared with epoetin beta: UT-7 and CD34+ cell stimulation assays. Poster presented at: The American Society of Nephrology 39th Annual Meeting; November 14-19, 2006; San Diego, Calif.
    • (2006) The American Society of Nephrology 39th Annual Meeting
    • Jarsch, M.1    Kubbies, M.2    Lanzendörfer, M.3    Haselbeck, A.4    Brandt, M.5
  • 19
    • 34248212532 scopus 로고    scopus 로고
    • CERA (continuous erythropoiesis receptor activator) for the treatment of renal anemia: An innovative agent with unique receptor binding characteristics and prolonged serum half-life. Poster
    • presented at: November 12-17, San Diego, Calif
    • Macdougall IC, Bailon P, Tare N, Pahlke W, Pill J, Brandt M. CERA (continuous erythropoiesis receptor activator) for the treatment of renal anemia: An innovative agent with unique receptor binding characteristics and prolonged serum half-life. Poster presented at: The American Society of Nephrology 36th Annual Meeting; November 12-17, 2003; San Diego, Calif.
    • (2003) The American Society of Nephrology 36th Annual Meeting
    • Macdougall, I.C.1    Bailon, P.2    Tare, N.3    Pahlke, W.4    Pill, J.5    Brandt, M.6
  • 20
    • 34248217851 scopus 로고    scopus 로고
    • CERA (continuous erythropoiesis receptor activator), an innovative erythropoietic agent: Dose-dependent response in phase I studies. Poster
    • presented at: May 31-June 3, Chicago, Ill
    • Reigner B, Jordan P, Pannier A, Glaspy J. CERA (continuous erythropoiesis receptor activator), an innovative erythropoietic agent: Dose-dependent response in phase I studies. Poster presented at: American Society of Clinical Oncology 39th Annual Meeting; May 31-June 3, 2003; Chicago, Ill.
    • (2003) American Society of Clinical Oncology 39th Annual Meeting
    • Reigner, B.1    Jordan, P.2    Pannier, A.3    Glaspy, J.4
  • 21
    • 34248223430 scopus 로고    scopus 로고
    • Continuous erythropoietin receptor activator (CERA) provides dose-dependent erythropoietic activity with a prolonged half-life in healthy volunteers. Poster
    • presented at: October 29-November 2, Vienna, Austria
    • Dougherty FC, Reigner B, Jordan P, Pannier A. Continuous erythropoietin receptor activator (CERA) provides dose-dependent erythropoietic activity with a prolonged half-life in healthy volunteers. Poster presented at: 29th European Society for Medical Oncology Congress; October 29-November 2, 2004; Vienna, Austria.
    • (2004) 29th European Society for Medical Oncology Congress
    • Dougherty, F.C.1    Reigner, B.2    Jordan, P.3    Pannier, A.4
  • 22
    • 34248150700 scopus 로고    scopus 로고
    • Pharmacologic profile of CERA (continuous erythropoietin receptor activator) in chronic kidney disease (CKD) patients following intravenous (IV) and subcutaneous (SC) administration. Poster
    • presented at: November 8-13, Philadelphia, Pa
    • Macdougall IC, Robson R, Opatrna S, et al. Pharmacologic profile of CERA (continuous erythropoietin receptor activator) in chronic kidney disease (CKD) patients following intravenous (IV) and subcutaneous (SC) administration. Poster presented at: The American Society of Nephrology 38th Annual Meeting; November 8-13,2005; Philadelphia, Pa.
    • (2005) The American Society of Nephrology 38th Annual Meeting
    • Macdougall, I.C.1    Robson, R.2    Opatrna, S.3
  • 23
    • 33750973533 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of intravenous and subcutaneous continuous erythropoietin receptor activator (CERA) in patients with chronic kidney disease
    • Macdougall IC, Robson R, Opatrna S, et al. Pharmacokinetics and pharmacodynamics of intravenous and subcutaneous continuous erythropoietin receptor activator (CERA) in patients with chronic kidney disease. Clin J Am Soc Nephrol. 2006;1:1211-1215.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 1211-1215
    • Macdougall, I.C.1    Robson, R.2    Opatrna, S.3
  • 25
    • 34248184317 scopus 로고    scopus 로고
    • Dose-dependent erythropoietic responses to subcutaneous (SC) CERA (continuous erythropoietin receptor activator) in a multi-dose study of patients with chronic kidney disease not on dialysis. Poster
    • presented at: November 8-13, Philadelphia, Pa
    • Besarab A, Provenzano R, Macdougall IC, et al. Dose-dependent erythropoietic responses to subcutaneous (SC) CERA (continuous erythropoietin receptor activator) in a multi-dose study of patients with chronic kidney disease not on dialysis. Poster presented at: The American Society of Nephrology 38th Annual Meeting; November 8-13, 2005; Philadelphia, Pa.
    • (2005) The American Society of Nephrology 38th Annual Meeting
    • Besarab, A.1    Provenzano, R.2    Macdougall, I.C.3
  • 26
    • 34248191562 scopus 로고    scopus 로고
    • Subcutaneous CERA (continuous erythropoietin receptor activator) maintains hemoglobin levels with administration intervals up to 3 weeks in chronic kidney disease patients not on dialysis. Poster
    • presented at: November 8-13, Philadelphia, Pa
    • Provenzano R, Besarab A, Macdougall IC, et al. Subcutaneous CERA (continuous erythropoietin receptor activator) maintains hemoglobin levels with administration intervals up to 3 weeks in chronic kidney disease patients not on dialysis. Poster presented at: The American Society of Nephrology 38th Annual Meeting; November 8-13, 2005; Philadelphia, Pa.
    • (2005) The American Society of Nephrology 38th Annual Meeting
    • Provenzano, R.1    Besarab, A.2    Macdougall, I.C.3
  • 29
    • 34248179318 scopus 로고    scopus 로고
    • Dose-dependent erythropoietic responses to subcutaneous CERA (continuous erythropoiesis receptor activator) in a multiple-dose study of dialysis patients with chronic renal anemia. Poster
    • presented at: May 15-18, Lisbon, Portugal
    • Dougherty FC, Reigner B, Beyer U. Dose-dependent erythropoietic responses to subcutaneous CERA (continuous erythropoiesis receptor activator) in a multiple-dose study of dialysis patients with chronic renal anemia. Poster presented at: 41st European Renal Association-European Dialysis and Transplant Association Congress; May 15-18, 2004; Lisbon, Portugal.
    • (2004) 41st European Renal Association-European Dialysis and Transplant Association Congress
    • Dougherty, F.C.1    Reigner, B.2    Beyer, U.3
  • 32
    • 34248154042 scopus 로고    scopus 로고
    • Canaud B, Braun J, Locatelli F, et al; on behalf of the STRIATA Study Investigators. Intravenous (IV) CERA (continuous erythropoietin receptor activator) administered once every 2 weeks maintains stable haemoglobin (Hb) levels in patients with chronic kidney disease (CKD) on dialysis. Poster presented at: 43rd European Renal Association-European Dialysis and Transplant Association Congress; July 15-18, 2006; Glasgow, Scotland.
    • Canaud B, Braun J, Locatelli F, et al; on behalf of the STRIATA Study Investigators. Intravenous (IV) CERA (continuous erythropoietin receptor activator) administered once every 2 weeks maintains stable haemoglobin (Hb) levels in patients with chronic kidney disease (CKD) on dialysis. Poster presented at: 43rd European Renal Association-European Dialysis and Transplant Association Congress; July 15-18, 2006; Glasgow, Scotland.
  • 33
    • 34248156024 scopus 로고    scopus 로고
    • Sulowicz W, Locatelli F, Balla J, et al; on behalf of the PROTOS Study Investigators. Subcutaneous (SC) CERA (continuous erythropoietin receptor activator) administered once every 2 weeks or once monthly maintains haemoglobin (Hb) levels in patients with chronic kidney disease (CKD) on dialysis. Poster presented at: 43rd European Renal Association-European Dialysis and Transplant Association Congress; July 15-18, 2006; Glasgow, Scotland.
    • Sulowicz W, Locatelli F, Balla J, et al; on behalf of the PROTOS Study Investigators. Subcutaneous (SC) CERA (continuous erythropoietin receptor activator) administered once every 2 weeks or once monthly maintains haemoglobin (Hb) levels in patients with chronic kidney disease (CKD) on dialysis. Poster presented at: 43rd European Renal Association-European Dialysis and Transplant Association Congress; July 15-18, 2006; Glasgow, Scotland.
  • 39
    • 34248232268 scopus 로고    scopus 로고
    • The safety and tolerability profile of continuous erythropoietin receptor activator (CERA) in patients with chronic kidney disease on dialysis is characteristic of this patient population. Poster
    • presented at: June 26-30, Singapore
    • Dougherty FC, Beyer U. The safety and tolerability profile of continuous erythropoietin receptor activator (CERA) in patients with chronic kidney disease on dialysis is characteristic of this patient population. Poster presented at: The 3rd World Congress of Nephrology; June 26-30, 2005; Singapore.
    • (2005) The 3rd World Congress of Nephrology
    • Dougherty, F.C.1    Beyer, U.2
  • 40
    • 34248191042 scopus 로고    scopus 로고
    • No changes in blood pressure in dialysis patients after 12 months of treatment with IV or SC CERA (continuous erythropoietin receptor activator). Poster
    • presented at: June 26-30, Singapore
    • Dougherty FC, Beyer U. No changes in blood pressure in dialysis patients after 12 months of treatment with IV or SC CERA (continuous erythropoietin receptor activator). Poster presented at: The 3rd World Congress of Nephrology; June 26-30, 2005; Singapore.
    • (2005) The 3rd World Congress of Nephrology
    • Dougherty, F.C.1    Beyer, U.2
  • 41
    • 10744224729 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents and antibody-mediated pure red-cell aplasia: Where are we now and where do we go from here?
    • Locatelli F, Aljama P, Barany P, et al. Erythropoiesis-stimulating agents and antibody-mediated pure red-cell aplasia: Where are we now and where do we go from here? Nephrol Dial Transplant. 2004;19:288-293.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 288-293
    • Locatelli, F.1    Aljama, P.2    Barany, P.3


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