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Volumn 82, Issue 5, 2007, Pages 539-542

Statin wars - Emphasis on potency vs event reduction and safety?

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; EZETIMIBE; EZETIMIBE PLUS SIMVASTATIN; FLUINDOSTATIN; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVINOLIN; OMEPRAZOLE; PLACEBO; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; WARFARIN;

EID: 34248159606     PISSN: 00256196     EISSN: None     Source Type: Journal    
DOI: 10.4065/82.5.539     Document Type: Editorial
Times cited : (24)

References (26)
  • 1
    • 2542461241 scopus 로고    scopus 로고
    • Optimal low-density lipoprotein is 50 to 70 mg/dl: Lower is better and physiologically normal
    • O'Keefe JH Jr, Cordain L, Harris WH, Moe RM, Vogel R. Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal. J Am Coll Cardiol. 2004;43:2142-2146.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 2142-2146
    • O'Keefe Jr, J.H.1    Cordain, L.2    Harris, W.H.3    Moe, R.M.4    Vogel, R.5
  • 2
    • 15944410609 scopus 로고    scopus 로고
    • Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD et al, Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005;352:1425-1435.
    • (2005) N Engl J Med , vol.352 , pp. 1425-1435
    • LaRosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 3
    • 26844468578 scopus 로고    scopus 로고
    • Wiviott SD, Cannon CP, Morrow DA, Ray II, Pfeffer MA, Braunwald E, PROVE IT-TIMI 22 Investigators. Can low-density lipoprotein be too low? the safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy [published correction appears in J Am Coll Cardiol. 2006;47:472]. J Am Coll Cardiol. 2005;46:1411-1416.
    • Wiviott SD, Cannon CP, Morrow DA, Ray II, Pfeffer MA, Braunwald E, PROVE IT-TIMI 22 Investigators. Can low-density lipoprotein be too low? the safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy [published correction appears in J Am Coll Cardiol. 2006;47:472]. J Am Coll Cardiol. 2005;46:1411-1416.
  • 4
    • 3142729178 scopus 로고    scopus 로고
    • Grundy SM, Cleeman JI, Merz CN, et al, Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment III guidelines [published correction appears in Circulation. 2004;110:763]. Circulation. 2004;110:227-239.
    • Grundy SM, Cleeman JI, Merz CN, et al, Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment III guidelines [published correction appears in Circulation. 2004;110:763]. Circulation. 2004;110:227-239.
  • 5
    • 34248211864 scopus 로고    scopus 로고
    • Achieving low-density lipoprotein cholesterol goals in high-risk patients in managed care: Comparison of rosuvastatin, atorvastatin, and simvastatin in the SOLAR trial
    • Insull W Jr, Ghali JK, Hassman DR, Yeas JW, Gandhi SK, Miller E. Achieving low-density lipoprotein cholesterol goals in high-risk patients in managed care: comparison of rosuvastatin, atorvastatin, and simvastatin in the SOLAR trial. Mayo Clin Proc. 2007;82:543-550.
    • (2007) Mayo Clin Proc , vol.82 , pp. 543-550
    • Insull Jr, W.1    Ghali, J.K.2    Hassman, D.R.3    Yeas, J.W.4    Gandhi, S.K.5    Miller, E.6
  • 6
    • 0038645309 scopus 로고    scopus 로고
    • STELLAR Study Group. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR Trial)
    • Jones PH, Davidson MH, Stein EA, et al, STELLAR Study Group. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR Trial). Am J Cardiol. 2003; 92:152-160.
    • (2003) Am J Cardiol , vol.92 , pp. 152-160
    • Jones, P.H.1    Davidson, M.H.2    Stein, E.A.3
  • 7
    • 0032032592 scopus 로고    scopus 로고
    • Jones P, Kafonek S, Laurora I, Hunninghake D. Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) [published correction appears in Am J Cardiol. 1998;82:128]. Am J Cardiol. 1998;81:582-587.
    • Jones P, Kafonek S, Laurora I, Hunninghake D. Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study) [published correction appears in Am J Cardiol. 1998;82:128]. Am J Cardiol. 1998;81:582-587.
  • 8
    • 15944394012 scopus 로고    scopus 로고
    • Pitt B. Low-density lipoprotein cholesterol in patients with stable coronary heart disease - is it time to shift our goals? [editorial]. N Engl J Med. 2005 Apr 7;352:1483-1484. Epub 2005 Mar 8.
    • Pitt B. Low-density lipoprotein cholesterol in patients with stable coronary heart disease - is it time to shift our goals? [editorial]. N Engl J Med. 2005 Apr 7;352:1483-1484. Epub 2005 Mar 8.
  • 9
    • 33750531657 scopus 로고    scopus 로고
    • Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients
    • Catapano AL, Davidson MH, Ballantyne CM, et al. Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients. Curr Med Res Opin. 2006;22:2041-2053.
    • (2006) Curr Med Res Opin , vol.22 , pp. 2041-2053
    • Catapano, A.L.1    Davidson, M.H.2    Ballantyne, C.M.3
  • 10
    • 29244458390 scopus 로고    scopus 로고
    • Importance and management of dyslipidemia in the metabolic syndrome
    • Menuet R, Lavie CJ, Milani RV. Importance and management of dyslipidemia in the metabolic syndrome. Am J Med Sci. 2005;330:295-302.
    • (2005) Am J Med Sci , vol.330 , pp. 295-302
    • Menuet, R.1    Lavie, C.J.2    Milani, R.V.3
  • 11
    • 33750110780 scopus 로고    scopus 로고
    • Lipid therapy in the elderly - emphasis on clinical event reduction and safety
    • Lavie CJ, Milani RV. Lipid therapy in the elderly - emphasis on clinical event reduction and safety. Am J Geriatr Cardiol. 2006;15:245-247.
    • (2006) Am J Geriatr Cardiol , vol.15 , pp. 245-247
    • Lavie, C.J.1    Milani, R.V.2
  • 12
    • 33847404392 scopus 로고    scopus 로고
    • Piorkowski M, Fischer S, Stellbaum C, et al. Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: is sufficient cholesterol-lowering enough to inhibit platelets? J Am Coll Cardiol. 2007 Mar 13;49:1035-1042. Epub 2007 Feb 23.
    • Piorkowski M, Fischer S, Stellbaum C, et al. Treatment with ezetimibe plus low-dose atorvastatin compared with higher-dose atorvastatin alone: is sufficient cholesterol-lowering enough to inhibit platelets? J Am Coll Cardiol. 2007 Mar 13;49:1035-1042. Epub 2007 Feb 23.
  • 13
    • 34248228864 scopus 로고    scopus 로고
    • Implication of the new low-density lipoprotein goals in dyslipidemia management of patients with acute coronary syndrome
    • Kontos MC, Joyner SE, Roberts CS, et al. Implication of the new low-density lipoprotein goals in dyslipidemia management of patients with acute coronary syndrome. Mayo Clin Proc. 2007;82:551-555.
    • (2007) Mayo Clin Proc , vol.82 , pp. 551-555
    • Kontos, M.C.1    Joyner, S.E.2    Roberts, C.S.3
  • 14
    • 0037167661 scopus 로고    scopus 로고
    • MIRACL Study Investigators. Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: A Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy
    • Waters DD, Schwartz GG, Olsson AG, et al, MIRACL Study Investigators. Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy. Circulation. 2002; 106:1690-1695.
    • (2002) Circulation , vol.106 , pp. 1690-1695
    • Waters, D.D.1    Schwartz, G.G.2    Olsson, A.G.3
  • 15
    • 4544243333 scopus 로고    scopus 로고
    • A to Z Investigators. Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: Phase Z of the A to Z trial
    • de Lemos JA, Blazing MA, Wiviott SD, et al, A to Z Investigators. Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes: phase Z of the A to Z trial. JAMA. 2004;292:1307-1316.
    • (2004) JAMA , vol.292 , pp. 1307-1316
    • de Lemos, J.A.1    Blazing, M.A.2    Wiviott, S.D.3
  • 16
    • 11344279659 scopus 로고    scopus 로고
    • Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Investigators. C-reactive protein levels and outcomes after statin therapy
    • Ridker PM, Cannon CP, Morrow D, et al, Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) Investigators. C-reactive protein levels and outcomes after statin therapy. N Engl J Med. 2005;352:20-28.
    • (2005) N Engl J Med , vol.352 , pp. 20-28
    • Ridker, P.M.1    Cannon, C.P.2    Morrow, D.3
  • 17
    • 17844410923 scopus 로고    scopus 로고
    • Ballantyne CM, Abate N, Yuan Z, King TR, Palmisano J. Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study [published correction appears in Am Heart J. 2005;149:882]. Am Heart J. 2005;149:464-473.
    • Ballantyne CM, Abate N, Yuan Z, King TR, Palmisano J. Dose-comparison study of the combination of ezetimibe and simvastatin (Vytorin) versus atorvastatin in patients with hypercholesterolemia: the Vytorin Versus Atorvastatin (VYVA) study [published correction appears in Am Heart J. 2005;149:882]. Am Heart J. 2005;149:464-473.
  • 18
    • 33847021434 scopus 로고    scopus 로고
    • Ballantyne CM, Weiss R, Moccetti T, et al, EXPLORER Study Investigators. Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER Study). Am J Cardiol. 2007 Mar 1;99:673-680. Epub 2007 Jan 4.
    • Ballantyne CM, Weiss R, Moccetti T, et al, EXPLORER Study Investigators. Efficacy and safety of rosuvastatin 40 mg alone or in combination with ezetimibe in patients at high risk of cardiovascular disease (results from the EXPLORER Study). Am J Cardiol. 2007 Mar 1;99:673-680. Epub 2007 Jan 4.
  • 19
    • 0037504445 scopus 로고    scopus 로고
    • Ezetimibe Study Group. Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial
    • Ballantyne CM, Houri J, Notarbartolo A, et al, Ezetimibe Study Group. Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Circulation. 2003;107:2409-2415.
    • (2003) Circulation , vol.107 , pp. 2409-2415
    • Ballantyne, C.M.1    Houri, J.2    Notarbartolo, A.3
  • 20
    • 3142595570 scopus 로고    scopus 로고
    • Statin safety: What to know
    • Bottorff MB. Statin safety: what to know. Am J Geriatr Cardiol. 2004; 13(3, suppl 1):34-38.
    • (2004) Am J Geriatr Cardiol , vol.13 , Issue.3 and SUPPL. 1 , pp. 34-38
    • Bottorff, M.B.1
  • 21
    • 24144437144 scopus 로고    scopus 로고
    • Conversion to atorvastatin in patients intolerant or refractory to simvastatin therapy: The CAPISH study
    • Krasuski RA, Doeppenschmidt D, Henry JS, et al. Conversion to atorvastatin in patients intolerant or refractory to simvastatin therapy: the CAPISH study. Mayo Clin Proc. 2005;80:1163-1168.
    • (2005) Mayo Clin Proc , vol.80 , pp. 1163-1168
    • Krasuski, R.A.1    Doeppenschmidt, D.2    Henry, J.S.3
  • 22
    • 23944500869 scopus 로고    scopus 로고
    • Safety of high-dose atorvastatin therapy
    • 5A:69F-75F
    • Waters DD. Safety of high-dose atorvastatin therapy. Am J Cardiol. 2005;96(5A):69F-75F.
    • (2005) Am J Cardiol , pp. 96
    • Waters, D.D.1
  • 23
    • 4043154385 scopus 로고    scopus 로고
    • Assessment and treatment of lipids in elderly persons [editorial]
    • Lavie CJ. Assessment and treatment of lipids in elderly persons [editorial] . Am J Geriatr Cardiol. 2004;13(3, suppl 1):2-3.
    • (2004) Am J Geriatr Cardiol , vol.13 , Issue.3 and SUPPL. 1 , pp. 2-3
    • Lavie, C.J.1
  • 24
    • 20544432480 scopus 로고    scopus 로고
    • Alsheikh-Ali AA, Ambrose MS, Kuvin JT, Karas RH. The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis. Circulation. 2005 Jun 14;111:3051-3057. Epub 2005 May 23.
    • Alsheikh-Ali AA, Ambrose MS, Kuvin JT, Karas RH. The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis. Circulation. 2005 Jun 14;111:3051-3057. Epub 2005 May 23.
  • 25
    • 33645889332 scopus 로고    scopus 로고
    • McKenney JM, Davidson MH, Jacobson TA, Guyton JR. Final conclusions and recommendations of the National Lipid Association Statin Safety Assessment Task Force. Am J Cardiol. 2006 Apr 17;97(8A):89C-94C. Epub 2006 Feb 28.
    • McKenney JM, Davidson MH, Jacobson TA, Guyton JR. Final conclusions and recommendations of the National Lipid Association Statin Safety Assessment Task Force. Am J Cardiol. 2006 Apr 17;97(8A):89C-94C. Epub 2006 Feb 28.
  • 26
    • 33645887517 scopus 로고    scopus 로고
    • Kasiske BL, Wanner C, O'Neill WC. An assessment of statin safety by nephrologists. Am J Cardiol. 2006 Apr 17;97(8A):82C-85C. Epub 2006 Feb 9.
    • Kasiske BL, Wanner C, O'Neill WC. An assessment of statin safety by nephrologists. Am J Cardiol. 2006 Apr 17;97(8A):82C-85C. Epub 2006 Feb 9.


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