Nose-to-brain delivery of TS-002, prostaglandin D2 analogue

Journal of Drug Targeting

Volumn 15, Issue 1, 2007, Pages 59-66

  Yamada, Kenji ^a   Hasegawa, Masatoshi ^b   Kametani, Shunichi ^b   Ito, Shusei ^b  

^a Research Strategy Division   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Brain targeting; Natural sleep inducer; Nose to brain delivery; Prostaglandin D2 analogue; TS 002

Indexed keywords

PROSTAGLANDIN D2 DERIVATIVE; TS 002; UNCLASSIFIED DRUG; HYPNOTIC SEDATIVE AGENT; PROSTAGLANDIN D2; TS-002;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; DRY POWDER; MALE; MONKEY; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; SLEEP INDUCTION; ANIMAL; AREA UNDER THE CURVE; BIOAVAILABILITY; BLOOD BRAIN BARRIER; BRAIN; DRUG DELIVERY SYSTEM; DRUG EFFECT; INTRANASAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MACACA; METABOLISM; NEBULIZER; POWDER; RAT; SLEEP; SPRAGUE DAWLEY RAT;

ADMINISTRATION, INTRANASAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; BLOOD-BRAIN BARRIER; BRAIN; DRUG DELIVERY SYSTEMS; HYPNOTICS AND SEDATIVES; INJECTIONS, INTRAVENOUS; MACACA FASCICULARIS; MALE; NEBULIZERS AND VAPORIZERS; POWDERS; PROSTAGLANDIN D2; RATS; RATS, SPRAGUE-DAWLEY; SLEEP;

EID: 34248159319     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860601029496     Document Type: Article

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