Disialotransferrin, determined by capillary electrophoresis, is an accurate biomarker for alcoholic cause of acute pancreatitis

Pancreas

Volumn 34, Issue 4, 2007, Pages 405-409

  Methuen, Taina ^a   Kylänpää, Leena ^b   Kekäläinen, Otto ^a   Halonen, Toivo ^c   Tukiainen, Eija ^b   Sarna, Seppo ^a   Kemppainen, Esko ^b   Haapiainen, Reijo ^b   Puolakkainen, Pauli ^b   Salaspuro, Mikko ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Acute pancreatitis; Alcohol consumption; Diagnosis; Disialotransferrin; Transferrin isoforms

Indexed keywords

ALANINE AMINOTRANSFERASE; AMYLASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; GAMMA GLUTAMYLTRANSFERASE; TRANSFERRIN;

ACUTE PANCREATITIS; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOLIC PANCREATITIS; AMYLASE BLOOD LEVEL; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CAPILLARY ELECTROPHORESIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ERYTHROCYTE; ERYTHROCYTE VOLUME; FEMALE; HOSPITAL ADMISSION; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROBABILITY; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; ROC CURVE; STATISTICAL SIGNIFICANCE; TRANSFERRIN BLOOD LEVEL;

ACUTE DISEASE; ADULT; AGED; ALANINE TRANSAMINASE; AMYLASES; AREA UNDER CURVE; ASPARTATE AMINOTRANSFERASES; BILIARY TRACT DISEASES; BILIRUBIN; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; DIAGNOSIS, DIFFERENTIAL; ELECTROPHORESIS, CAPILLARY; ERYTHROCYTE INDICES; FALSE POSITIVE REACTIONS; FEMALE; FINLAND; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; LIKELIHOOD FUNCTIONS; MALE; MIDDLE AGED; PANCREATITIS; PANCREATITIS, ALCOHOLIC; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; ROC CURVE; SENSITIVITY AND SPECIFICITY; SIALOGLYCOPROTEINS; TIME FACTORS; TRANSFERRIN;

EID: 34248158682     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318043c164     Document Type: Article

References (27)

1. Gullo L, Migliori M, Olah A, et al. Acute pancreatitis in five European countries: etiology and mortality. Pancreas. 2002;24:223-227.
2. Somogyi L, Martin SP, Venkatesan T, et al. Recurrent acute pancreatitis: an algorithmic approach to identification and elimination of inciting factors. Gastroenterology. 2001;120:708-717.
3. Andersen JM, Hedstrom J, Kemppainen E, et al. The ratio of trypsin-2-alpha(1)-antitrypsin to trypsinogen-1 discriminates biliary and alcohol-induced acute pancreatitis. Clin Chem. 2001;47:231-236.
4. Aparicio JR, Viedma JA, Aparisi L, et al. Usefulness of carbohydrate-deficient transferrin and trypsin activity in the diagnosis of acute alcoholic pancreatitis. Am J Gastroenterol. 2001;96:1777-1781.
5. Jaakkola M, Sillanaukee P, Lof K, et al. Blood tests for detection of alcoholic cause of acute pancreatitis. Lancet. 1994;343:1328-1329.
6. Smotkin J, Tenner S. Laboratory diagnostic tests in acute pancreatitis. J Clin Gastroenterol. 2002;34:459-462.
7. Stibler H. Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed. Clin Chem. 1991;37:2029-2037.
8. Stibler H, Borg S, Joustra M. A modified method for the assay of carbohydrate-deficient transferrin (CDT) in serum. Alcohol Alcohol. 1991;(suppl 1):451-454.
9. Turpeinen U, Methuen T, Alfthan H, et al. Comparison of HPLC and small column (CDTect) methods for disialotransferrin. Clin Chem. 2001;47:1782-1787.
10. Bortolotti F, De Paoli G, Pascali JP, et al. Analysis of carbohydrate-deficient transferrin: comparative evaluation of turbidimetric immunoassay, capillary zone electrophoresis, and HPLC. Clin Chem. 2005;51:2368-2371.
11. Helander A, Wielders JPM, te Stroet R, et al. Comparison of HPLC and capillary electrophoresis for confirmatory testing of the alcohol misuse marker carbohydrate-deficient transferrin. Clin Chem. 2005;51:1528-1531.
12. Helander A, Husa A, Jeppsson JO. Improved HPLC method for carbohydrate-deficient transferrin in serum. Clin Chem. 2003;49:1881-1890.
13. Schwan R, Loiseaux M-N, Albuisson E, et al. Performance of asialotransferrin in detecting alcohol abuse. Alcohol Clin Exp Res. 2005;29:81-83.
14. Bradley EL 3rd. A clinically based classification system for acute pancreatitis. Summary of the international symposium on acute pancreatitis, Atlanta, Ga, September 11 through 13, 1992. Arch Surg. 1993;128:586-590.
15. Bossuyt PM, Reitsma JB, Bruns DE, et al. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Clin Chem. 2003;49:1-6.
16. Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA. 1994;271:703-707.
17. Solberg HE. The theory of reference values part 5. Statistical treatment of collected reference values. Determination of reference limits. J Clin Chem Clin Biochem. 1983;21:749-760.
18. Moons KG, van Es GA, Deckers JW, et al. Limitations of sensitivity, specificity, likelihood ratio, and bayes' theorem in assessing diagnostic probabilities: a clinical example. Epidemiology. 1997;8:12-17.
19. Moons KG, Biesheuvel CJ, Grobbee DE. Test research versus diagnostic research. Clin Chem. 2004;50:473-476.
20. Stenman UH. Immunoassay standardization: Is it possible, who is responsible, who is capable? Clin Chem. 2001;47:815-820.
21. Arndt T, Hackler R, Kleine TO, et al. Validation by isoelectric focusing of the anion-exchange isotransferrin fractionation step involved in determination of carbohydrate-deficient transferrin by the CDTect assay. Clin Chem. 1998;44:27-34.
22. Alden A, Ohlson S, Pahlsson P, et al. HPLC analysis of carbohydrate-deficient transferrin isoforms isolated by the axis-shield %CDT method. Clin Chim Acta. 2005;356:143-146.
23. Dufour MC, Adamson MD. The epidemiology of alcohol-induced pancreatitis. Pancreas. 2003;27:286-290.
24. Jaakkola M, Sillanaukee P, Lof K, et al. Amount of alcohol is an important determinant of the severity of acute alcoholic pancreatitis. Surgery. 1994;115:31-38.
25. Jaakkola M, Frey T, Sillanaukee P, et al. Acute pancreatic injury in asymptomatic individuals after heavy drinking over the long-term. Hepatogastroenterology. 1994;41:477-482.
26. Kristenson H, Trell E. Indicators of alcohol consumption: comparisons between a questionnaire (mm-MAST), interviews and serum gamma-glutamyl transferase (GGT) in a health survey of middle-aged males. Br J Addict. 1982;77:297-304.
27. Anttila P, Jarvi K, Latvala J, et al. Diagnostic characteristics of different carbohydrate-deficient transferrin methods in the detection of problem drinking: effects of liver disease and alcohol consumption. Alcohol Alcohol. 2003;38:415-420.