Pharmacokinetics of terbinafine in the rabbit ocular tissues after topical administration

Ophthalmic Research

Volumn 39, Issue 2, 2007, Pages 81-83

  Sun, X G ^a,b   Wang, Z X ^a   Wang, Z Q ^a   Deng, S J ^a   Li, R ^a   Luo, S Y ^a   Wu, Y Y ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF OPHTHALMOLOGY   (China)

Author keywords

Antifungal agents; Fungal keratitis, rabbit; Terbinafine, pharmacokinetics

Indexed keywords

CORN OIL; TERBINAFINE; ANTIFUNGAL AGENT; NAPHTHALENE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CONJUNCTIVA; CORNEA; EYE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; RABBIT; ANIMAL; BIOAVAILABILITY; METABOLISM; TISSUE DISTRIBUTION; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; ANTIFUNGAL AGENTS; AQUEOUS HUMOR; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CORNEA; NAPHTHALENES; RABBITS; TISSUE DISTRIBUTION;

EID: 34248147600     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000099242     Document Type: Article

References (5)

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4. Denouel J, Keller HP, Schaub P, et al: Determination of terbinafine and its desmethyl metabolite in human plasma by high-performance liquid chromatography. J Chromatogr B Biomed Appl 1995;663:353-359.
5. Faergemann J, Zehender H, Denouel J, et al: Levels of terbinafine in plasma, stratum corneum, dermis-epidermis (without stratum corneum), sebum, hair and nails during and after 250 mg terbinafine orally once per day for four weeks. Acta Derm Venereol 1993;73:305-309.