Renalase is a novel renal hormone that regulates cardiovascular function

Journal of the American Society of Hypertension

Volumn 1, Issue 2, 2007, Pages 99-103

  Desir, Gary V ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

amine oxidase; Blood pressure regulation; catecholamines metabolism; renal failure

Indexed keywords

ADRENALIN; AMINE OXIDASE (FLAVIN CONTAINING); CATECHOLAMINE; KIDNEY HORMONE; NORADRENALIN; RENALASE; UNCLASSIFIED DRUG;

BLOOD PRESSURE; BLOOD VESSEL TONE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR SYSTEM; CHRONIC KIDNEY DISEASE; CIRCULATION; ENDOCRINE SYSTEM; ENZYME BLOOD LEVEL; ENZYME RELEASE; HEART MUSCLE CONTRACTILITY; HEART RATE; HEMODIALYSIS; HORMONE ACTION; HUMAN; IN VITRO STUDY; KIDNEY FAILURE; KIDNEY FUNCTION; MORBIDITY; MORTALITY; PRIORITY JOURNAL; REGULATORY MECHANISM; RENAL REPLACEMENT THERAPY; REVIEW; SYMPATHETIC TONE;

EID: 34248141770     PISSN: 19331711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jash.2006.12.001     Document Type: Review

References (28)

1. Brenner B.M., Deen W.M., and Robertson C.R. Determinants of glomerular filtration rate. Annu Rev Physiol 38 (1976) 11-19
2. Lin F.K., Suggs S., Lin C.H., et al. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci U S A 82 (1985) 7580-7584
3. Jacobs K., Shoemaker C., Rudersdorf R., et al. Isolation and characterization of genomic and cDNA clones of human erythropoietin. Nature 313 (1985) 806-810
4. Persson P.B. Renin: origin, secretion and synthesis. J Physiol 552 (2003) 667-671
5. Humes H.D. Acute renal failure: prevailing challenges and prospects for the future. Kidney Int Suppl 50 (1995) S26-S32
6. Wolfe R.A., Ashby V.B., Milford E.L., et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 341 (1999) 1725-1730
7. Oberg B.P., McMenamin E., Lucas F.L., et al. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int 65 (2004) 1009-1016
8. Koomans H.A., Blankestijn P.J., and Joles J.A. Sympathetic hyperactivity in chronic renal failure: a wake-up call. J Am Soc Nephrol 15 (2004) 524-537
9. Joles J.A., and Koomans H.A. Causes and consequences of increased sympathetic activity in renal disease. Hypertension 43 (2004) 699-706
10. Anavekar N.S., McMurray J.J., Velazquez E.J., et al. Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction. N Engl J Med 351 (2004) 1285-1295
11. Go A.S., Chertow G.M., Fan D., McCulloch C.E., and Hsu C.Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351 (2004) 1296-1305
12. DiBona G.F. Neural control of renal function: role of renal alpha adrenoceptors. J Cardiovasc Pharmacol 7 suppl 8 (1985) S18-S23
13. Vallbo A.B., Hagbarth K.E., Torebjork H.E., and Wallin B.G. Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol Rev 59 (1979) 919-957
14. Converse Jr. R.L., Jacobsen T.N., Toto R.D., et al. Sympathetic overactivity in patients with chronic renal failure. N Engl J Med 327 (1992) 1912-1918
15. Klein I.H., Ligtenberg G., Neumann J., Oey P.L., Koomans H.A., and Blankestijn P.J. Sympathetic nerve activity is inappropriately increased in chronic renal disease. J Am Soc Nephrol 14 (2003) 3239-3244
16. DiBona G.F. Neural control of renal function: cardiovascular implications. Hypertension 13 (1989) 539-548
17. Recordati G.M., Moss N.G., and Waselkov L. Renal chemoreceptors in the rat. Circ Res 43 (1978) 534-543
18. Ziegler M.G., Morrissey E.C., Kennedy B., and Elayan H. Sources of urinary catecholamines in renal denervated transplant recipients. J Hypertens 8 (1990) 927-931
19. Xu J., Li G., Wang P., et al. Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. J Clin Invest 115 (2005) 1275-1280
20. Strausberg R.L., Feingold E.A., Klausner R.D., and Collins F.S. The mammalian gene collection. Science 286 (1999) 455-457
21. Binda C., Mattevi A., and Edmondson D.E. Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase. J Biol Chem 277 (2002) 23973-23976
22. Jalkanen S., and Salmi M. Cell surface monoamine oxidases: enzymes in search of a function. Embo J 20 (2001) 3893-3901
23. Binda C., Newton-Vinson P., Hubalek F., Edmondson D.E., and Mattevi A. Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders. Nat Struct Biol 9 (2002) 22-26
24. Ghosh S.S., Gehr T.W.B., Sica D.A., et al. Effect of renalase inhibition on blood pressure. J Am Soc Nephrol 17 (2006) 208A
25. Ghosh S.S., Gehr T.W.B., Sica D.A., et al. Renalase regulates blood pressure in salt sensitive Dahl rats. J Am Soc Nephrol 17 (2006) 208A
26. Zoccali C., Mallamaci F., Tripepi G., et al. Norepinephrine and concentric hypertrophy in patients with end-stage renal disease. Hypertension 40 (2002) 41-46
27. Zoccali C., Mallamaci F., Parlongo S., et al. Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease. Circulation 105 (2002) 1354-1359
28. Hausberg M., Kosch M., Harmelink P., et al. Sympathetic nerve activity in end-stage renal disease. Circulation 106 (2002) 1974-1979