Glucose administration downregulates lipoprotein lipase activity in vivo: A study using repeated intravenous fat tolerance test

Physiological Research

Volumn 56, Issue 2, 2007, Pages 175-181

  Jindrichova E ^a,b   Kratochvilova S ^a   Kovar J ^a,b  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b Centre for Experimental Cardiovascular Research   (Czech Republic)

Author keywords

Glucose; Insulin; Intravenous fat tolerance test; Lipoprotein lipase; Triglyceride

Indexed keywords

FATTY ACID; INSULIN; LIPID EMULSION; LIPOPROTEIN LIPASE; TRIACYLGLYCEROL;

ADULT; ARTICLE; BLOOD; DOWN REGULATION; EVALUATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HUMAN; MALE; METABOLISM; REFERENCE VALUE;

ADULT; BLOOD GLUCOSE; DOWN-REGULATION; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS, NONESTERIFIED; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; LIPOPROTEIN LIPASE; MALE; REFERENCE VALUES; TRIGLYCERIDES;

EID: 34247891680     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. ARASARADNAM MP, MORGAN L, WRIGHT J, GAMA R: Diurnal variation in lipoprotein lipase activity. Ann Clin Biochem 39: 136-139, 2002.
2. BENGTSSON-OLIVECRONA G, OLIVECRONA T: Assay of lipoprotein lipase and hepatic lipase. In: Lipoprotein Analysis. A Practical Approach. RE SKINNER, CA CONVERSE (eds), Oxford University Press, Oxford, 1992, pp 169-185.
3. COHEN JC, BERGER GM: Effects of glucose ingestion on postprandial lipemia and triglyceride clearance in humans. J Lipid Res 31: 597-602, 1990.
4. ECKEL RH: Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N Engl J Med 320: 1060-1068, 1989.
5. FARESE Jr RV, YOST TJ, ECKEL RH: Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans. Metabolism 40: 214-216, 1991.
6. GENUTH S, ALBERTI KG, BENNETT P, BUSE J, DEFRONZO R, KAHN R, KITZMILLER J, KNOWLER WC, LEBOVITZ H, LERNMARK A, NATHAN D, PALMER J, RIZZA R, SAUDEK C, SHAW J, STEFFES M, STERN M, TUOMILEHTO J, ZIMMET P: Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 26: 3160-3167, 2003.
7. GOLDBERG IJ: Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J Lipid Res 37: 693-707, 1996.
8. HULTIN M, BENGTSSON-OLIVECRONA G, OLIVECRONA T: Release of lipoprotein lipase to plasma by triacylglycerol emulsions. Comparison to the effect of heparin. Biochim Biophys Acta 1125: 97-103, 1992.
9. KARPE F, OLIVECRONA T, WALLDIUS G, HAMSTEN A: Lipoprotein lipase in plasma after an oral fat load: relation to free fatty acids. J Lipid Res 33: 975-984, 1992.
10. KOVÁŘ J, FEJFAROVÁ V, PELIKÁNOVÁ T, POLEDNE R: Hyperglycemia downregulates total lipoprotein lipase activity in humans. Physiol Res 53: 61-68, 2004.
11. LEWIS B, BOBERG J, MANCINI M, CARLSON LA: Determination of the intravenous fat tolerance test with Intralipid® by nephelometry. Atherosclerosis 15: 83-86, 1972.
12. LEWIS GF, UFFELMAN KD, SZETO LW, STEINER G: Effects of acute hyperinsulinemia on VLDL triglyceride and VLDL apoB production in normal weight and obese individuals. Diabetes 42: 833-842, 1993.
13. LITHELL H, BOBERG J, HELLSING K, LUNDQVIST G, VESSBY B: Lipoprotein-lipase activity in human skeletal muscle and adipose tissue in the fasting and the fed states. Atherosclerosis 30: 89-94, 1978.
14. MEAD JR, IRVINE SA, RAMJI DP: Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med 80: 753-769, 2002.
15. OLIVECRONA T, OLIVECRONA G: Lipoprotein and hepatic lipase in lipoprotein metabolism. In: Lipoproteins in Health and Disease. DJ BETTERIDGE, DR ILLINGWORTH, J SHEPHERD (eds), Arnold, London, 1999, pp 223-246.
16. ONG JM, KERN PA: The role of glucose and glycosylation in the regulation of lipoprotein lipase synthesis and secretion in rat adipocytes. J Biol Chem 264: 3177-3182, 1989.
17. PETERSON J, BIHAIN BE, BENGTSSON-OLIVECRONA G, DECKELBAUM RJ, CARPENTIER YA, OLIVECRONA T: Fatty acid control of lipoprotein lipase: A link between energy metabolism and lipid transport. Proc Natl Acad Sci USA 87: 909-913, 1990.
18. RÖSSNER S: Studies on intravenous fat tolerance test. Methodological, experimental, and clinical experiences with Intralipid. Acta Med Scand Suppl 564: 1-24, 1974.
19. RUGE T, SVENSSON A, ERIKSSON JW, OLIVECRONA T, OLIVECRONA G: Food deprivation increases postheparin lipoprotein lipase activity in humans. Eur J Clin Invest 31: 1040-1047, 2001.
20. RUGE T, SVENSSON A, ERIKSSON JW, OLIVECRONA T: Tissue-specific regulation of lipoprotein lipase in humans: effects of fasting. Eur J Clin Invest 35: 194-200, 2005.
21. SADUR CN, ECKEL RH: Insulin stimulation of adipose tissue lipoprotein lipase. Use of the euglycemic clamp technique. J Clin Invest 69: 1119-1125, 1982.
22. SAXENA, U, WITTE LD, GOLDBERG IJ: Release of endothelial cell lipoprotein lipase by plasma lipoproteins and free fatty acids. J Biol Chem 264: 4349-4355, 1989.
23. SEMENKOVICH CF, WIMS M, NOE L, ETIENNE J, CHAN L: Insulin regulation of lipoprotein lipase activity in 3T3-L1 adipocytes is mediated at posttranscriptional and posttranslational levels. J Biol Chem 264: 9030-9038, 1989.
24. YKI-JÄRVINEN H, TASKINEN M-R, KOIVISTO VA, NIKKILÄ EA: Response of adipose tissue lipoprotein lipase activity to acute hyperinsulinaemia in man. Diabetologia 27: 364-369, 1984.
25. ZECHNER R: The tissue-specific expression of lipoprotein lipase: implications for energy and lipoprotein metabolism. Curr Opin Lipidol 8: 77-88, 1997.