Acidic residues on the voltage-sensor domain determine the activation of the NaChBac sodium channel

Biophysical Journal

Volumn 92, Issue 10, 2007, Pages 3513-3523

  Blanchet, Jonathan ^a   Pilote, Sylvie ^a   Chahine, Mohamed ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CYSTEINE; GLUTAMIC ACID; LYSINE; SHAKER POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

AMINO ACID TRANSPORT; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRIC POTENTIAL; HUMAN; HUMAN CELL; PATCH CLAMP; PROTEIN DOMAIN; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; SODIUM CURRENT;

EID: 34247880407     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1529/biophysj.106.090464     Document Type: Article

References (40)

1. Hille, B. 2001. Ion channels of excitable membranes. Sinauer Associates, Sunderland, MA.
2. Ren, D., B. Navarro, H. Xu, L. Yue, Q. Shi, and D. E. Clapham. 2001. A prokaryotic voltage-gated sodium channel. Science. 294:2372-2375.
3. Pavlov, E., C. Bladen, R. Winkfein, C. Diao, P. Dhaliwal, and R. J. French. 2005. The pore, not cytoplasmic domains, underlies inactivation in a prokaryotic sodium channel. Biophys. J. 89:232-242.
4. Yue, L., B. Navarro, D. Ren, A. Ramos, and D. E. Clapham. 2002. The cation selectivity filter of the bacterial sodium channel, NaChBac. J. Gen. Physiol. 120:845-853.
5. Long, S. B., E. B. Campbell, and R. MacKinnon. 2005. Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science. 309:903-908.
6. Murata, Y., H. Iwasaki, M. Sasaki, K. Inaba, and Y. Okamura. 2005. Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature. 435:1239-1243.
7. Sasaki, M., M. Takagi, and Y. Okamura. 2006. A voltage sensor-domain protein is a voltage-gated proton channel. Science. 312:589-592.
8. Ramsey, I. S., M. M. Moran, J. A. Chong, and D. E. Clapham. 2006. A voltage-gated proton-selective channel lacking the pore domain. Nature. 440:1213-1216.
9. Bezanilla, F. 2000. The voltage sensor in voltage-dependent ion channels. Physiol. Rev. 80:555-592.
10. + channel in voltage-sensing. J. Membr. Biol. 201:9-24.
11. + channel. Neuron. 14:1293-1301.
12. + channel. Neuron. 16:1159-1167.
13. Tiwari-Woodruff, S.K., C. T. Schulteis, A. F. Mock, and D. M. Papazian. 1997. Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits. Biophys. J. 72:1489-1500.
14. Keynes, R. D., and F. Elinder. 1999. The screw-helical voltage gating of ion channels. Proc. R. Soc. Lond. B Biol. Sci. 266:843-852.
15. Pradhan, P., R. Ghose, and M. E. Green. 2005. Voltage gating and anions, especially phosphate: a model system. Biochim. Biophys. Acta. 1717:97-103.
16. Green, M. E. 2005. A possible role for phosphate in complexing the arginines of S4 in voltage gated channels. J. Theor. Biol. 233:337-341.
17. + channel. Nature. 423:33-41.
18. Monticelli, L., K. M. Robertson, J. L. MacCallum, and D. P. Tieleman. 2004. Computer simulation of the KvAP voltage-gated potassium channel: steered molecular dynamics of the voltage sensor. FEBS Lett. 564:325-332.
19. Kumar, S., and R. Nussinov. 2002. Close-range electrostatic interactions in proteins. ChemBioChem. 3:604-617.
20. Margolskee, R. F., B. McHendry-Rinde, and R. Horn. 1993. Panning transfected cells for electrophysiological studies. Biotechniques. 15:906-911.
21. Jurman, M. E., L. M. Boland, Y. Liu, and G. Yellen. 1994. Visual identification of individual transfected cells for electrophysiology using antibody-coated beads. Biotechniques. 17:876-881.
22. Chenna, R., H. Sugawara, T. Koike, R. Lopez, T. J. Gibson, D. G. Higgins, and J. D. Thompson. 2003. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31:3497-3500.
23. Notredame, C., D. G. Higgins, and J. Heringa. 2000. T-Coffee: a novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302:205-217.
24. Zhorov, B. S., and P. D. Bregestovski. 2000. Chloride channels of glycine and GABA receptors with blockers: Monte Carlo minimization and structure-activity relationships. Biophys. J. 78:1786-1803.
25. Zhorov, B. S. 1983. Topography of the active site of the noradrenaline neuronal membrane carrier based on the theoretical conformation analysis of inhibitors of neuronal catecholamine uptake. Bioorg. Khim. 9:200-215.
26. Weiner, S. J., P. A. Kollman, D. A. Case, U. C. Singh, C. Ghio, G. Alagona, S. Profeta Jr., and P. Weiner. 1984. A new force field for molecular mechanical simulation of nucleic acids and proteins. J. Am. Chem. Soc. 106:765-784.
27. Brooks, C. L. I., B. M. Pettitt, and M. Karplus. 1985. Structural and energetic effects of truncating long ranged interactions in ionic and polar fluids. J. Chem. Phys. 83:5897-5908.
28. Lazaridis, T., and M. Karplus. 1999. Effective energy function for proteins in solution. Proteins. 35:133-152.
29. Li, Z., and H. A. Scheraga. 1987. Monte Carlo-minimization approach to the multiple-minima problem in protein folding. Proc. Natl. Acad. Sci. USA. 84:6611-6615.
30. 2+ ions and dihydropyridine ligand. Biophys. J. 70:22-37.
31. Zhorov, B. S., and S. X. Lin. 2000. Monte Carlo-minimized energy profile of estradiol in the ligand-binding tunnel of 17 beta-hydroxysteroid dehydrogenase: atomic mechanisms of steroid recognition. Proteins. 38:414-427.
32. + channel selectively modulates channel gating. Proc. Natl. Acad. Sci. USA. 92:9422-9426.
33. + channel. Science. 309:897-903.
34. Starace, D. M., and F. Bezanilla. 2004. A proton pore in a potassium channel voltage sensor reveals a focused electric field. Nature. 427:548-553.
35. + channel. Cell. 123:463-475.
36. Kumar, S., and R. Nussinov. 1999. Salt bridge stability in monomeric proteins. J. Mol. Biol. 293:1241-1255.
37. Treptow, W., and M. Tarek. 2006. Environment of the gating charges in the Kv1.2 Shaker potassium channel. Biophys. J. 90:L64-L66.
38. Yarov-Yarovoy, V., D. Baker, and W. A. Catterall. 2006. Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels. Proc. Natl. Acad. Sci. USA. 103:7292-7297.
39. Elliott, D. J. S., E. J. Neale, Q. Aziz, J. P. Dunham, T. S. Munsey, M. Hunter, and A. Sivaprasadarao. 2004. Molecular mechanism of voltage sensor movements in a potassium channel. EMBO J. 23:4717-4726.
40. Blunck, R., D. M. Starace, A. M. Correa, and F. Bezanilla. 2004. Detecting rearrangements of Shaker and NaChBac in real-time with fluorescence spectroscopy in patch-clamped mammalian cells. Biophys. J. 86:3966-3980.