BNIPL-2 promotes the invasion and metastasis of human hepatocellular carcinoma cells

Oncology Reports

Volumn 17, Issue 3, 2007, Pages 605-610

  Xie, Li ^a,b   Qin, Wenxin ^a   Li, Jinjun ^a   He, Xianghuo ^a   Zhang, Haitao ^c   Yao, Genfu ^a   Shu, Huiqun ^a   Yao, Ming ^a   Wan, Dafang ^a   Gu, Jianren ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANDONG CANCER HOSPITAL AND INSTITUTE   (China)

^c DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

BNIPL 2; Cancer metastasis; Invasion

Indexed keywords

BNIPL PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BIOSYNTHESIS; CANCER INVASION; EXPERIMENTAL NEOPLASM; GENETIC TRANSFECTION; HUMAN; IMMUNOBLOTTING; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; METASTASIS; MOUSE; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; HUMANS; IMMUNOBLOTTING; LIVER NEOPLASMS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASMS, EXPERIMENTAL; TRANSFECTION;

EID: 34247876046     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.17.3.605     Document Type: Article

References (26)

1. Pantel K and Brakenhoff RH: Dissecting the metastatic cascade. Nat Rev Cancer 4: 448-456, 2004. (Pubitemid 38745530)
2. Couzin J: Medicine. Tracing the steps of metastasis, cancer's menacing ballet. Science 299: 1002-1006, 2003.
3. Friedl P and Wolf K: Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 3: 362-374, 2003. (Pubitemid 37328856)
4. Etienne-Manneville S and Hall A: Rho GTPases in cell biology. Nature 420: 629-635, 2002. (Pubitemid 36764489)
5. Qin W, Hu J, Guo M, et al: BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis. Biochem Biophys Res Commun 308: 379-385, 2003. (Pubitemid 36939186)
6. Shang X, Zhou YT and Low BC: Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1. J Biol Chem 278: 45903-45914, 2003. (Pubitemid 37432736)
7. Tang ZY, Ye SL, Liu YK, et al: A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol 130: 187-196, 2004.
8. Albini A, Iwamoto Y, K leinman HK, et al: A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47: 3239-3245, 1987. (Pubitemid 17082655)
9. Andre F, Rigot V, Remacle-Bonnet M, Luis J, Pommier G and Marvaldi J: Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells. Gastroenterology 116: 64-77, 1999. (Pubitemid 29013495)
10. Lu X, Qin W, Li J, et al: The growth and metastasis of human hepatocellular carcinoma xenografts are inhibited by small interfering RNA targeting to the subunit ATP6L of proton pump. Cancer Res 65: 6843-6849, 2005. (Pubitemid 41060723)
11. Sander EE, ten Klooster JP, van Delft S, van der Kammen RA and Collard JG: Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 147: 1009-1022, 1999.
12. Fenteany G, Janmey PA and Stossel TP: Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. Curr Biol 10: 831-838, 2000. (Pubitemid 30597202)
13. Pisani P, Parkin DM, Bray F and Ferlay J: Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83: 18-29, 1999. (Pubitemid 29409471)
14. Ye QH, Qin LX, Forgues M, et al: Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 9: 416-423, 2003. (Pubitemid 36460075)
15. Sahai E and Marshall CJ: RHO-GTPases and cancer. Nat Rev Cancer 2: 133-142, 2002.
16. Schmitz AA, Govek EE, Bottner B and Van Aelst L: Rho GTPases: signaling, migration, and invasion. Exp Cell Res 261: 1-12, 2000.
17. Aruffo A, Stamenkovic I, Melnick M, Underhill CB and Seed B: CD44 is the principal cell surface receptor for hyaluronate. Cell 61: 1303-1313, 1990.
18. Goldstein LA, Zhou DF, Picker LJ, et al: A human lymphocyte homing receptor, the hermes antigen, is related to cartilage proteoglycan core and link proteins. Cell 56: 1063-1072, 1989. (Pubitemid 19091018)
19. Thomas L, Byers HR, Vink J and Stamenkovic I: CD44H regulates tumor cell migration on hyaluronate-coated substrate. J Cell Biol 118: 971-977, 1992.
20. Svee K, White J, Vaillant P, et al: Acute lung injury fibroblast migration and invasion of a fibrin matrix is mediated by CD44. J Clin Invest 98: 1713-1727, 1996. (Pubitemid 26359187)
21. Yu Q and Stamenkovic I: Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev 13: 35-48, 1999. (Pubitemid 29045114)
22. Takahashi K, Eto H and Tanabe KK: Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells. Int J Cancer 80: 387-395, 1999. (Pubitemid 29019625)
23. Gunthert U, Hofmann M, Rudy W, et al: A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 65: 13-24, 1991. (Pubitemid 121001209)
24. Kawano Y, Okamoto I, Murakami D, et al: Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins. J Biol Chem 275: 29628-29635, 2000. (Pubitemid 32043842)
25. Okamoto I, Kawano Y, Matsumoto M, et al: Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins. J Biol Chem 274: 25525-25534, 1999.
26. Okamoto I, Kawano Y, Tsuiki H, et al: CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration. Oncogene 18: 1435-1446, 1999. (Pubitemid 29103631)