Use of recombinant activated factor VII in a patient with severe thrombocytopenia due to myelodysplastic syndrome with uncontrolled gastrointestinal bleeding [1]

Blood Coagulation and Fibrinolysis

Volumn 18, Issue 4, 2007, Pages 385-386

  Ozcelik, T ^a   Ozkocaman, V ^a   Ozkalemkas, F ^a   Ali, R ^a   Altundal, Y ^a   Ozkan, A ^a   Tunali, A ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; MEPREDNISONE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; SOMATOSTATIN; TRANEXAMIC ACID;

AGED; BLOOD CLOTTING; BLOOD TRANSFUSION; BONE MARROW BIOPSY; CASE REPORT; CAUSE OF DEATH; DISEASE CONTROL; DISEASE SEVERITY; ERYTHROCYTE TRANSFUSION; GASTROINTESTINAL HEMORRHAGE; HUMAN; HUMAN TISSUE; LABORATORY TEST; LETTER; MALE; MELENA; MYELODYSPLASTIC SYNDROME; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; SUPERIOR MESENTERIC ANGIOGRAPHY; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; TREATMENT RESPONSE;

AGED; BLOOD COAGULATION FACTORS; FACTOR VIIA; GASTROINTESTINAL HEMORRHAGE; HUMANS; MALE; MYELODYSPLASTIC SYNDROMES; RECOMBINANT PROTEINS; THROMBOCYTOPENIA;

EID: 34247862211     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e32809cc96c     Document Type: Letter

References (6)

1. Erhardtsen E. Ongoing NovoSeven® trials. Intensive Care Med 2002; 28:248-255.
2. White B, McHale J, Ravi N, Reynolds J, Stephens R, Moriarty J, Smith OP. Successful use of recombinant FVIIa (NovoSeven®) in the management of intractable post-surgical intra-abdominal haemorrhage. Br J Haematol 1999; 107:677-678.
3. Gerotziafas GT, Zervas C, Gavrielidis G, Tokmaktsis A, Hatjiharissi E, Papaioannou M, et al. Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage. Am J Hematol 2002; 69:219-222.
4. Barnes C, Blanchette V, Canning P, Carcao M. Recombinant FVIIa in the management of intracerebral haemorrhage in severe thrombocytopenia unresponsive to platelet-enhancing treatment. Transfus Med 2005; 15:145-150.
5. Goodnough LT. Experiences with recombinant human factor VIIa in patients with thrombocytopenia. Semin Hematol 2004; 41:25-29.
6. Poon MC. Management of thrombocytopenic bleeding: is there a role for recombinant coagulation factor VIIa? Curr Hematol Rep 2003; 2:139-147.