The 29-kilodalton thiol-dependent peroxidase of Entamoeba histolytica is a factor involved in pathogenesis and survival of the parasite during oxidative stress

Eukaryotic Cell

Volumn 6, Issue 4, 2007, Pages 664-673

  Sen, Abhik ^a   Chatterjee, Nabendu Sekhar ^a   Ali Akbar, M ^a,c   Nandi, Nilay ^a   Das, Pradeep ^a,b  

^a NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

^b RAJENDRA MEMORIAL RESEARCH INSTITUTE OF MEDICAL SCIENCES   (India)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; PEROXIDASE; PROTOZOAL PROTEIN; REACTIVE OXYGEN METABOLITE; TETRACYCLINE; THIOL DEPENDENT PEROXIDASE; THIOL-DEPENDENT PEROXIDASE; UNCLASSIFIED DRUG;

AMEBIASIS; ANIMAL; ARTICLE; CELL DEATH; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ENTAMOEBA HISTOLYTICA; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; LIVER AMEBIASIS; METABOLISM; MOLECULAR WEIGHT; OXIDATIVE STRESS; PARASITE; PARASITOLOGY; PATHOGENICITY; PHAGOCYTOSIS; PHYSIOLOGY; SURVIVAL; TROPHOZOITE;

ANIMALS; CELL DEATH; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENTAMOEBA HISTOLYTICA; ENTAMOEBIASIS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIVER ABSCESS, AMEBIC; MOLECULAR WEIGHT; OXIDATIVE STRESS; PARASITES; PEROXIDASES; PHAGOCYTOSIS; PROTOZOAN PROTEINS; REACTIVE OXYGEN SPECIES; RNA, ANTISENSE; SURVIVAL ANALYSIS; TETRACYCLINE; TROPHOZOITES;

CRICETINAE; ENTAMOEBA HISTOLYTICA;

EID: 34247862179     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00308-06     Document Type: Article

References (37)

1. Akbar, M. A., N. S. Chatterjee, P. Sen, A. Debnath, A. Pal, T. Bera, and P. Das. 2004. Genes induced by a high oxygen environment in Entamoeba histolytica. Mol. Biochem. Parasitol. 133:187-196.
2. Alon, R, N., R. Bracha, and D. Mirelman. 1997. Inhibition of expression of the lysine-rich 30 kDa surface antigen of Entamoeba dispar by the transcription of its antisense RNA. Mol. Biochem. Parasitol. 90:193-201.
3. Ankri, S., F. Padilla-Vaca, T. Stolarsky, L. Koole, U. Katz, and D. Mirelman. 1999. Antisense inhibition of expression of the light subunit (35 kDa) of the Gal/GalNAc lectin complex inhibits Entamoeba histolytica virulence. Mol. Microbiol. 33:327-337.
4. Bourre, L., S. Thibaut, A. Briffaud, N. Rousset, S. Eleouet, Y. Lajat, and T. Patrice. 2002. Indirect detection of photosensitizer ex vivo. J. Photochem. Pholobiol. B 67:23-31.
5. Bracha, R., and D. Mirelman. 1984. Virulence of Entamoeba histolytica trophozoiles: effect of bacteria, microaerobic condition, and metronidazole. J. Exp. Med. 160:353-368.
6. Bracha, R., Y. Nuchamowitz, M. Leippe, and D. Mirelman. 1999. Antisense inhibition of amoebapore expression in Entamoeba histolytica causes a decrease in amoebic virulence. Mol. Microbiol. 34:463-472.
7. Bracha, R., Y. Nuchamowitz, and D. Mirelman. 2003. Transctiptional silencing of an amoebapore gene in Entamoeba histolytica: molecular analysis and effect on pathogenesis. Eukaryot. Cell 2:295-305.
8. Bruchhaus, I., and E. Tannich. 1993. Analysis of the genomic sequence encoding the 29-kDa cysteine-rich protein of Entamoeba histolytica. Trop. Med. Parasitol. 44:116-118.
9. Bruchhaus, I., and E. Tannich. 1994. Induction of the iron-containing superoxide dismutase in Entamoeba histolytica by a superoxide anion-generating system or by iron chelation. Mol. Biochem. Parasitol. 67:281-288.
10. Bruchhaus, I., and K. Tannich. 1995. Identification of an Entamoeba histolytica gene encoding a protein homologous to prokaryotic disulphide oxidoreductases. Mol. Biochem. Parasitol. 70:187-191.
11. Bruchhaus, I., S. Richter, and E. Tannich. 1997. Removal of hydrogen peroxide by the 29 kDa protein of Entamoeba histolytica. Biochem. J. 326: 785-789.
12. Bruchhaus, I., S. Richter, and E. Tannich. 1998. Recombinant expression and biochemical characterization of an NADPH:flavin oxidoreductase from Entamoeba histolytica. Biochem. J. 330:1217-1221.
13. Choi, M. H., D. Sajed, L. Poole, K. Hirata, S. Herdman, B. E. Torian, and S. L. Reed. 2005. An unusual surface peroxiredoxin protects invasive Entamoeba histolytica from oxidant attack. Mol. Biochem. Parasitol. 143:80-89.
14. Clark, I. A., N. U. Hunt, and W. B. Cowden. 1986. Oxygen derived free radicals in the pathogenesis of parasitic diseases. Adv. Parasitol. 25:1-73.
15. Davis, P. H., X. Zhang, J. Guo, R. R. Townsend, and S. L. Stanley, Jr. 2006. Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulence. Mol. Microbiol. 61:1523-1532.
16. Diamond, L. S., D. R. Harlow, and C. C. Cunnick. 1978. A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba. Trans. R. Soc. Trop. Med. Hyg. 72:431-432.
17. Flores, B. M., M. A. Batze, M. A. Stein, C. Petersen, D. L. Diedrich, and B. E. Torian. 1993. Structural analysis and demonstration of the 29-kDa antigen of pathogenic Entamoeba histolytica as the major accessible free thiol-containing surface protein. Mol. Microbiol. 7:755-763.
18. Hamann, L., H. Buss, and E. Tannich. 1997. Tetracycline-controllcd gene expression in Entamoeba histolytica. Mol. Biochem. Parasitol. 84:83-91.
19. Hellberg, A., R. Nickel, H. Lotter, E. Tannich, and I. Bruchhaus. 2001. Overexpression of cysteine proteinase 2 in Entamoeba histolytica or Entamoeba dispar increases amoeba-induced monolayer destruction in vitro but does not augment amoebic liver abscess formation in gerbils. Cell Microbiol. 3:13-20.
20. Hughes, M., C. Lee, C. Holm, S. Ghosh, A. Mills, L. A. Lockhart, S. Reed, and B. Mann. 2003. Identification of Entamoeba histolytica thiol-specific antioxidant as a GaINAc lectin-associatecl protein. Mol. Biochem. Parasitol. 127:113-120.
21. Katz, U., R. Bracha, Y. Nuchamowitz, O. Milstein, and D. Mirelman. 2003. Comparison between constitutive and inducible plasmid vectors used for Kene expression in Entamoeba histolytica. Mol. Biochem. Parasitol. 128:229-233.
22. Leippe, M., J. Andra, and H. J. Müller-Eberhard. 1994. Cytolytic and antibacterial activity of synthetic peptides derived from amoebapore, the pore forming peptide of E. histolytica. Proc. Natl. Acad. Sci. USA 91:2602-2606.
23. Leippe, M. 1995. Spontaneous release of cysteine proteinases but not of pore-forming peptides by viable Entamoeba histolytica. Parasitology 111: 569-574.
24. Moshitch-Moshkovitch, S., R. Petter, A. Levitan, T. Stolarsky, and D. Mirelman. 1998. Regulation of expression of ribosomal protein L-21 genes of Entamoeba histolytica and E. dispar is at the post-transcriptional level. Mol. Microbiol. 27:677-685.
25. Mossman, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63.
26. Murray, H. W., S. B. Aley, and W. A. Scott. 1981. Susceptibility of Entamoeba histolytica to oxygen intermediates. Mol. Biochem. Parasitol. 3:381-391.
27. Nickel, R., and E. Tannich. 1994. Transfection and transient expression of chloramphenicol acetyltransferase gene in the protozoan parasite Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 91:7095-7098.
28. Purdy, J. E., B. J. Mann, E. T. Pho, and W. A. Petri, Jr. 1994. Transient transfection of the enteric parasite Entamoeba histolytica and expression of firefly luciferase. Proc. Natl. Acad. Sci. USA 91:7099-7103.
29. Ramakrishnan, G., R. R. Vines, B. J. Mann, and W. A. Petri, Jr. 1997. A tetracycline-inducible gene expression system in Entamoeba histolytica. Mol. Biochem. Parasitol. 84:93-100.
30. Ravdin, J. I. 1988. Human infection by Entamoeba histolytica, p. 166-176. In J. I. Ravdin (ed.), Amoebiasis: human infection. John Wiley, New York, NY.
31. Reed, S. L., B. M. Flores, M. A. Batzer, M. A. Stein, V. L. Stroeber, J. E. Carlton, D. L. Diedrich, and B. E. Tarian. 1992. Molecular and cellular characterization of the 29-kilodalton peripheral membrane protein of Entamoeba histolytica: differentiation between pathogenic and nonpathogenic isolates. Infect. Immun. 60:542-549.
32. Sahoo, N., S. Bhattacharya, and A. Bhattacharya. 2003. Blocking the expression of a calcium binding protein of the protozoan parasite Entamoeba histolytica by tetracycline regulatable antisense-RNA. Mol. Biochem. Parasitol. 126:281-284.
33. Sengupta, K., P. Das, T. M. Johnson, P. P. Chaudhuri, D. Das, and G. B. Nair. 1993. Production and characterization of monoclonal antibodies against a highly immunogenic fraction of Entamoeba histolytica (NIH:200) and their application in the detection of current amoebic infection. J. Eukaryot. Microbiol. 40:722-726.
34. Sengupta, K., V. I. Hernandez-Ramirez, A. Rios, R. Mondragon, and P. Talamas-Rohana, 2001. Entamoeba histolytica: monoclonal antibody against the β1 integrin-like molecule (140 kDa) inhibits cell adhesion to extracellular matrix components. Exp. Parasitol. 98:83-89.
35. Soong, C. J., B. E. Torian, M. D. Abd-Alla, T. F. Jackson, V. Gatharim, and J. I. Ravdin. 1995. Protection of gerbils from amebic liver abscess by immunization with recombinant Entamoeba histolytica 29-kilodalton antigen. Infect. Immun. 63:472-477.
36. Wagner, A., A. Marc, and J. M. Engasser. 1992. The use of lactate dehydrogenase (LDH) release kinetics for the evaluation of death and growth of mammalian cells in perfusion reactors. Biotechnol. Bioeng. 39:320-326.
37. World Health Organization. 1998. The World Health Report 1998. Life in the 21st century: a vision for all. World Health Organization, Geneva, Switzerland.