Mapping temporally varying quantitative trait loci in time-to-failure experiments

Genetics

Volumn 175, Issue 2, 2007, Pages 855-865

  Johannes, Frank ^a,b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DOWN REGULATION; EXPERIMENTAL STUDY; GENE MAPPING; GENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SIMULATION; UPREGULATION; BACTERIAL GENOME; BIOLOGICAL MODEL; CHROMOSOME MAP; COMPUTER SIMULATION; CONFIDENCE INTERVAL; CROSS BREEDING; GENETICS; PROPORTIONAL HAZARDS MODEL; STATISTICS; SURVIVAL; TIME;

CHROMOSOME MAPPING; COMPUTER SIMULATION; CONFIDENCE INTERVALS; CROSSES, GENETIC; GENOME, BACTERIAL; GENOTYPE; MODELS, GENETIC; PROPORTIONAL HAZARDS MODELS; QUANTITATIVE TRAIT LOCI; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 34247849316     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.106.059808     Document Type: Article

References (28)

1. ABRAHAMOWICZ, M., T. MACKENZIE and J. M. ESDAILE, 1996 Time-dependent hazard ratio: modeling hypothesis testing with application in lupus nephritis. J. Am. Stat. Assoc. 91: 1432-1439.
2. BOYARTCHUK, V. L., K. W. BROMAN, R. E. MOSHER, S. E. F. D'ORAZIO, M. N. STARNBACH et al., 2001 Multigenic control of Listeria monocytogenes susceptibility in mice. Nat. Genet. 27: 259-260.
3. BROMAN, K. W., 2003 Mapping quantitative trait loci in the case of a spike in the phenotype distribution. Genetics 163: 1169-1175.
4. CHANG-XING, M., G. CASELLA and R. WU, 2002 Functional mapping of quantitative trait loci underlying the character process: a theoretical framework. Genetics 161: 1751-1762.
5. CHEVERUD, J. M., E. J. ROUTMAN, F. A. M. DUARTE, B. VAN SWINDEREN, K. GOTHRAN et al., 1996 Quantitative trait loci for murine growth. Genetics 142: 1305-1319.
6. CHURCHILL, G. A., and R. W. DOERGE, 1994 Empirical threshold values for quantitative trait mapping. Genetics 138: 963-971.
7. COX, D. R., 1972 Regression methods and life-tables (with discussion). J. R. Stat. Soc. Ser. B 34: 187-220.
8. COX, D. R., 1975 Partial likelihood. Biometrika 62: 269-276.
9. DIAO, G., and D. Y. LIN, 2005 Semiparametric methods for mapping quantitative trait loci with censored data. Biometrics 61: 789-798.
10. DIAO, G., D. Y. LIN and F. ZOU, 2004 Mapping quantitative trait loci with censored observations. Genetics 168: 1689-1698.
11. FLEMING, T. R., J. R. O'FALLON, P. C. O'BRIAN and D. P. HARRINGTON, 1980 Modified Kolmogorov-Smirnov test procedure with applications to arbitrary right-censored data. Biometrics 36: 607-625.
12. GRAMBSCH, P. M., and T. M. THERNEAU, 1994 Proportional hazards tests and diagnostics based on weighted residuals. Biometrika 81: 515-526.
13. HENCKAERTS, E., H. GEIGER, C. J. LANGER, P. REBOLLO, G. VAN ZANT et al., 2002 Genetically determined variation in the number of phenotypically defined hematopoietic progenitor and stem cells and in their response to early acting cytokines. Blood 99: 3947-3954.
14. JOHANNES, F., D. A. BLIZARD, A. LIONIKAS, D. H. LANG, D. J. VANDENBERGH et al., 2006 QTL influencing baseline hematocrit in the C57BL/6J and DBA/2J lineage: age-related effects. Mamm. Genome 17: 689-699.
15. KLEIN, J. P., and M. L. MOESCHBERGER, 1997 Survival Analysis: Techniques for Censored and Truncated Data. Springer, New York.
16. LEHMANN, E. L., 1975 Nonparametrics: Statistical Methods Based on Ranks. Holden-Day, San Francisco.
17. LIONIKAS, A., D. A. BLIZARD, D. J. VANDENBERGH, M. G. GLOVER, J. T. STOUT et al., 2003 Genetic architecture of fast- and slow-twitch skeletal muscle weight in 200-day-old mice of the C57BL/6J and DBA/2J lineage. Physiol. Genomics 16: 141-152.
18. MORENO, C. R., J. M. ELSEN, P. LE ROY and V. DUCROCQ, 2005 Interval mapping methods for detecting QTL affecting survival and time-to-event phenotypes. Genet. Res. 85: 139-149.
19. SCHEMPER, M., 1992 Cox analysis of survival data with non-proportional hazard functions. Statistician 41: 455-465.
20. SCHOENFELD, D., 1981 The asymptotic properties of nonparametric tests for comparing survival distributions. Biometrika 68: 316-319.
21. SCHOENFELD, D., 1982 Partial residuals for the proportional hazards regression model. Biometrika 69: 239-241.
22. SCHOENFELD, D., 1983 Sample-size formula for the proportional-hazards regression model. Biometrics 39: 499-503.
23. TABLEMAN, M., and J. S. KIM, 2004 Survival Analysis Using S: Analysis of Time-to-Event Data. Chapman & Hall/CRC, Boca Raton, FL.
24. THERNEAU, T. M., and P. M. GRAMBSCH, 2000 Modeling Survival Data: Extending the Cox Model. Springer, New York.
25. WU, R., and M. LIN, 2006 Functional mapping - how to map and study the genetic architecture of dynamic complex traits. Nat. Rev. Genet. 7: 229-237.
26. WU, R., C.-X. MA, J. ZHU and G. CASELLA, 2002 Mapping epigenetic quantitative trait loci (QTL) altering a developmental trajectory. Genome 45: 28-33.
27. WU, W., Y. ZHOU, W. LI, D. MAO and Q. CHEN, 2002 Mapping of quantitative trait loci based on growth models. Theor. Appl. Genet. 105: 1043-1049.
28. WU, R., C.-X. MA, M. LIN, Z. WANG and G. CASELLA, 2004 Functional mapping of quantitative trait loci underlying growth trajectories using the transform-both-sides of the logistic model. Biometrics 60: 729-738.