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Volumn 24, Issue 1, 2006, Pages 25-32

Pharmacological profile of U-37883A, a channel blocker of smooth muscle-type ATP-sensitive K+ channels

Author keywords

ATP sensitive K+ channels; Channel blocker; Inwardly rectified K+ channels; Tissue selectivity; U 37883A; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; GLIMEPIRIDE; ION CHANNEL; N (1 ADAMANTYL) N' CYCLOHEXYL 4 MORPHOLINECARBOXAMIDINE; NATEGLINIDE; POTASSIUM CHANNEL; SULFONYLUREA DERIVATIVE; TOLBUTAMIDE; ADAMANTANE; DIURETIC AGENT; DRUG DERIVATIVE; MORPHOLINE DERIVATIVE; POTASSIUM CHANNEL BLOCKING AGENT;

EID: 34247849292     PISSN: 08975957     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3466.2006.00025.x     Document Type: Review
Times cited : (24)

References (27)
  • 1
    • 0032788372 scopus 로고    scopus 로고
    • Molecular biology of adenosine triphospate-sensitive potassium channels
    • Aguilar-Bryan L, Bryan J. Molecular biology of adenosine triphospate-sensitive potassium channels. Endocrine Rev 1999 20 : 101 135.
    • (1999) Endocrine Rev , vol.20 , pp. 101-135
    • Aguilar-Bryan, L.1    Bryan, J.2
  • 2
    • 0028927388 scopus 로고
    • A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic-cells
    • Akiyoshi M, Kakei M, Nakazaki M, et al. A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic-cells. Am J Physiol 1995 268 : E185 E193.
    • (1995) Am J Physiol , vol.268
    • Akiyoshi, M.1    Kakei, M.2    Nakazaki, M.3
  • 3
    • 0023911193 scopus 로고
    • Adenosine 5′-triphosphate-sensitive potassium channels
    • Ashcroft FM. Adenosine 5′-triphosphate-sensitive potassium channels. Annu Rev Neurosci 1988 11 : 97 118.
    • (1988) Annu Rev Neurosci , vol.11 , pp. 97-118
    • Ashcroft, F.M.1
  • 4
    • 0027305489 scopus 로고
    • K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells
    • Beech DJ, Zhang H, Nakao K, et al. K channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells. Br J Pharmacol 1993 110 : 573 582.
    • (1993) Br J Pharmacol , vol.110 , pp. 573-582
    • Beech, D.J.1    Zhang, H.2    Nakao, K.3
  • 5
    • 0037371267 scopus 로고    scopus 로고
    • N ateglinide, a D-phenylalanine derivative lacking either a sulfonyl-urea or benzamido moiety, specifically inhibits pancreatic beta-cell-type KATP channels
    • Chachin M, Yamada M, Fujita A, et al. N ateglinide, a D-phenylalanine derivative lacking either a sulfonyl-urea or benzamido moiety, specifically inhibits pancreatic beta-cell-type KATP channels. J Pharmacol Exp Ther 2003 304 : 1025 1032.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1025-1032
    • Chachin, M.1    Yamada, M.2    Fujita, A.3
  • 6
    • 4243311744 scopus 로고
    • U -37883A: A structurally novel antagonist of the vascular KATP openers
    • Cipkus-Dubray L, Swirtz M, Khan S, et al. U -37883A: A structurally novel antagonist of the vascular KATP openers. FASEB J 1992 6 : A1777.
    • (1992) FASEB J , vol.6
    • Cipkus-Dubray, L.1    Swirtz, M.2    Khan, S.3
  • 7
    • 0035895255 scopus 로고    scopus 로고
    • A mechanism for ATP-sensitive potassium channel diversity: Functional coassembly of two pore-forming subunits
    • Cui Y, Giblin JP, Clapp LH, et al. A mechanism for ATP-sensitive potassium channel diversity: Functional coassembly of two pore-forming subunits. Proc Natl Acad Sci USA 2001 98 : 729 734.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 729-734
    • Cui, Y.1    Giblin, J.P.2    Clapp, L.H.3
  • 8
    • 0028098782 scopus 로고
    • F unctional receptors in Xenopus oocytes for U-37883A, a novel ATP-sensitive K+ channel blocker: Comparison with rat insulinoma cells
    • Guillemare E, Honore E, De Weille J, et al. F unctional receptors in Xenopus oocytes for U-37883A, a novel ATP-sensitive K+ channel blocker: Comparison with rat insulinoma cells. Mol Pharmacol 1994 46 : 139 145.
    • (1994) Mol Pharmacol , vol.46 , pp. 139-145
    • Guillemare, E.1    Honore, E.2    De Weille, J.3
  • 9
    • 0030014372 scopus 로고    scopus 로고
    • C ardiovascular effects of the KATP channel blocker U-37883A and structurally related morpholinoguanidines
    • Humphrey SJ, Smith MP, Cimini MG, et al. C ardiovascular effects of the KATP channel blocker U-37883A and structurally related morpholinoguanidines. Meth Find Exp Clin Pharmacol 1996 18 : 247 260.
    • (1996) Meth Find Exp Clin Pharmacol , vol.18 , pp. 247-260
    • Humphrey, S.J.1    Smith, M.P.2    Cimini, M.G.3
  • 10
    • 0029743412 scopus 로고    scopus 로고
    • A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel
    • Isomoto S, Kondo C, Yamada M, et al. A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel. J Biol Chem 1996 271 : 24321 24324.
    • (1996) J Biol Chem , vol.271 , pp. 24321-24324
    • Isomoto, S.1    Kondo, C.2    Yamada, M.3
  • 11
    • 1842611800 scopus 로고    scopus 로고
    • M olecular analysis of the subtype-selective inhibition of cloned KATP channels by PNU-37883A
    • Kovalev H, Quayle JM, Kamishima T, et al. M olecular analysis of the subtype-selective inhibition of cloned KATP channels by PNU-37883A. Br J Pharmacol 2004 141 : 867 873.
    • (2004) Br J Pharmacol , vol.141 , pp. 867-873
    • Kovalev, H.1    Quayle, J.M.2    Kamishima, T.3
  • 12
    • 0028281731 scopus 로고
    • M g2+ -dependent inhibition of KATP by sulphonylureas in CRI-G1 insulin-secreting cells
    • Lee K, Ozanne SE, Hales CN, et al. M g2+ -dependent inhibition of KATP by sulphonylureas in CRI-G1 insulin-secreting cells. Br J Pharmacol 1994 111 : 632 640.
    • (1994) Br J Pharmacol , vol.111 , pp. 632-640
    • Lee, K.1    Ozanne, S.E.2    Hales, C.N.3
  • 13
    • 0031879263 scopus 로고    scopus 로고
    • U -37883A potently inhibits dopamine-modulated K+ channels on rat striatal neurons
    • Lin YJ, Chen X, Freedman JE. U -37883A potently inhibits dopamine-modulated K+ channels on rat striatal neurons. Eur J Pharmacol 1998 352 : 335 341.
    • (1998) Eur J Pharmacol , vol.352 , pp. 335-341
    • Lin, Y.J.1    Chen, X.2    Freedman, J.E.3
  • 14
    • 0028956274 scopus 로고
    • R enal and vascular effects of chemically distinct ATP-sensitive K+ channel blockers in rats
    • Ludens JH, Clark MA, Smith MP, et al. R enal and vascular effects of chemically distinct ATP-sensitive K+ channel blockers in rats. J Cardiovasc Pharmacol 1995 25 : 404 409.
    • (1995) J Cardiovasc Pharmacol , vol.25 , pp. 404-409
    • Ludens, J.H.1    Clark, M.A.2    Smith, M.P.3
  • 15
    • 0028859267 scopus 로고
    • R eceptor binding characterization in kidney membrane of [3H]U-37883, a novel ATP-sensitive K+ channel blocker with diuretic/([a-z])atriuretic properties
    • Meisheri KD, Fosset M, Humphrey SJ, et al. R eceptor binding characterization in kidney membrane of [3H]U-37883, a novel ATP-sensitive K+ channel blocker with diuretic/([a-z])atriuretic properties. Mol Pharmacol 1994 47 : 155 163.
    • (1994) Mol Pharmacol , vol.47 , pp. 155-163
    • Meisheri, K.D.1    Fosset, M.2    Humphrey, S.J.3
  • 16
    • 0027425648 scopus 로고
    • 4-Morpholinecarboximidine-N-1-adamantyl-N′-cyclohexyl-hydrochloride (U-37883A): Pharmacological characterization of a novel antagonist of vascular ATP-sensitive K+ channel openers
    • Meisheri KD, Humphrey SJ, Khan SA, et al. 4-Morpholinecarboximidine-N-1- adamantyl-N′-cyclohexyl-hydrochloride (U-37883A): Pharmacological characterization of a novel antagonist of vascular ATP-sensitive K+ channel openers. J Pharmacol Exp Ther 1993 266 : 655 665.
    • (1993) J Pharmacol Exp Ther , vol.266 , pp. 655-665
    • Meisheri, K.D.1    Humphrey, S.J.2    Khan, S.A.3
  • 17
    • 0021086270 scopus 로고
    • A TP-regulated K+ channels in cardiac muscle
    • Noma A. A TP-regulated K+ channels in cardiac muscle. Nature 1983 305 : 147 148.
    • (1983) Nature , vol.305 , pp. 147-148
    • Noma, A.1
  • 18
    • 0033037098 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/([a-z])eceptor assemblies
    • Seino S. ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/([a-z])eceptor assemblies. Ann Rev Physiol 1999 61 : 337 362.
    • (1999) Ann Rev Physiol , vol.61 , pp. 337-362
    • Seino, S.1
  • 19
    • 0032719329 scopus 로고    scopus 로고
    • B lock of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A
    • Surah-Narwal S, Xu SZ, McHugh D, et al. B lock of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A. Br J Pharmacol 1999 128 : 667 672.
    • (1999) Br J Pharmacol , vol.128 , pp. 667-672
    • Surah-Narwal, S.1    Xu, S.Z.2    McHugh, D.3
  • 20
    • 33645824084 scopus 로고    scopus 로고
    • P hysiological roles of ATP-sensitive K+ channels in smooth muscle
    • Teramoto N. P hysiological roles of ATP-sensitive K+ channels in smooth muscle. J Physiol 2006 572 : 617 624.
    • (2006) J Physiol , vol.572 , pp. 617-624
    • Teramoto, N.1
  • 21
    • 9644255636 scopus 로고    scopus 로고
    • E ffects of U-37883A on intracellular Ca2+-activated large conductance K+ channels in pig proximal urethral myocytes
    • Teramoto N, Aishima M, Zhu HL, et al. E ffects of U-37883A on intracellular Ca2+-activated large conductance K+ channels in pig proximal urethral myocytes. Eur J Pharmacol 2004 506 : 1 7.
    • (2004) Eur J Pharmacol , vol.506 , pp. 1-7
    • Teramoto, N.1    Aishima, M.2    Zhu, H.L.3
  • 22
    • 27744445882 scopus 로고    scopus 로고
    • M ultiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra
    • Tomoda T, Yunoki T, Naito S, et al. M ultiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra. Eur J Pharmacol 2005 524 : 1 10.
    • (2005) Eur J Pharmacol , vol.524 , pp. 1-10
    • Tomoda, T.1    Yunoki, T.2    Naito, S.3
  • 23
    • 0028979336 scopus 로고
    • E ffects of a novel KATP channel blocker on renal tubule function and K+ channel activity
    • Wang T, Wang, WH, Klein-Robbenhaar, G, et al. E ffects of a novel KATP channel blocker on renal tubule function and K+ channel activity. J Pharmacol Exp Ther 1995 273 : 1382 1389.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 1382-1389
    • Wang, T.1    Wang, W.H.2    Klein-Robbenhaar, G.3
  • 24
    • 0008230260 scopus 로고    scopus 로고
    • I nhibition of vascular KATP channels by U-37883A: A comparison with cardiac and skeletal muscle
    • Wellman GC, Barrett-Jolley R, Koppel H, et al. I nhibition of vascular KATP channels by U-37883A: A comparison with cardiac and skeletal muscle. Br J Pharmacol 1999 128 : 909 916.
    • (1999) Br J Pharmacol , vol.128 , pp. 909-916
    • Wellman, G.C.1    Barrett-Jolley, R.2    Koppel, H.3
  • 26
    • 0030896647 scopus 로고    scopus 로고
    • S ulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel
    • Yamada M, Isomoto S, Matsumoto S, et al. S ulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel. J Physiol 1997 499 : 715 720.
    • (1997) J Physiol , vol.499 , pp. 715-720
    • Yamada, M.1    Isomoto, S.2    Matsumoto, S.3
  • 27
    • 0029924673 scopus 로고    scopus 로고
    • Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells
    • Zhang H-L, Bolton TB. Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells. Br J Pharmacol 1996 118 : 105 114.
    • (1996) Br J Pharmacol , vol.118 , pp. 105-114
    • Zhang, H.-L.1    Bolton, T.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.