Neutrophil elastase inhibitor (sivelestat) preserves antitumor immunity and reduces the inflammatory mediators associated with major surgery

Surgery Today

Volumn 37, Issue 5, 2007, Pages 359-365

  Akamoto, Shintaro ^a   Okano, Keiichi ^a   Sano, Takanori ^a   Yachida, Shinichi ^a   Izuishi, Kunihiko ^a   Usuki, Hisashi ^a   Wakabayashi, Hisao ^a   Suzuki, Yasuyuki ^a  

^a KAGAWA UNIVERSITY   (Japan)

Author keywords

Cytokine; Immunosuppressive acidic protein; Neutrophil elastase; Sivelestat; Surgical stress

Indexed keywords

IMMUNOSUPPRESSIVE ACID PROTEIN; INTERLEUKIN 6; SIVELESTAT;

ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CORRELATION ANALYSIS; FEMALE; HELPER CELL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; MALE; POSTOPERATIVE PERIOD; SURGICAL STRESS; TUMOR IMMUNITY;

AGED; AGED, 80 AND OVER; CARCINOMA, HEPATOCELLULAR; DIGESTIVE SYSTEM NEOPLASMS; DIGESTIVE SYSTEM SURGICAL PROCEDURES; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; FEMALE; GLYCINE; HUMANS; INTERLEUKIN-6; LEUKOCYTE ELASTASE; LIVER NEOPLASMS; MALE; MIDDLE AGED; PANCREATICODUODENECTOMY; POSTOPERATIVE PERIOD; PROSPECTIVE STUDIES; SERINE PROTEINASE INHIBITORS; SINGLE-BLIND METHOD; STRESS; SULFONAMIDES; TH1 CELLS; TH2 CELLS;

EID: 34247645072     PISSN: 09411291     EISSN: 14362813     Source Type: Journal    
DOI: 10.1007/s00595-006-3409-0     Document Type: Article

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