Assessing potency of c-Jun N-terminal kinase 3 (JNK3) inhibitors using 2D molecular descriptors and binary QSAR methodology

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 12, 2007, Pages 4256-4264

  Ijjaali, Ismail ^a   Petitet, François ^a   Dubus, Elodie ^a   Barberan, Olivier ^a   Michel, André ^a  

^a Aureus Pharma   (France)

Author keywords

2D molecular descriptors; Binary QSAR; JNK3 inhibitors

Indexed keywords

C JUN N TERMINAL KINASE 3 INHIBITOR; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 10; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BIOLOGICAL ACTIVITY; DATA EXTRACTION; DRUG POTENCY; ENZYME ACTIVITY; HYDROPHOBICITY; IC 50; KNOWLEDGE BASE; MODEL; MOLECULE; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SCREENING;

LIGANDS; MITOGEN-ACTIVATED PROTEIN KINASE 10; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34247644786     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.03.062     Document Type: Article

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