Heritability of Raynaud's phenomenon and vascular responsiveness to cold: A study of adult female twins

Arthritis Care and Research

Volumn 57, Issue 3, 2007, Pages 524-528

  Cherkas, L F ^a   Williams, F M K ^a   Carter, L ^a   Howell, K ^b   Black, C M ^b   Spector, T D ^a   MacGregor, A J ^b,c  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL EXAMINATION; COLD EXPOSURE; COLD SENSITIVITY; FEMALE; GENETIC MODEL; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; PROVOCATION TEST; RAYNAUD PHENOMENON; TWINS;

ADULT; BODY TEMPERATURE; COLD; DISEASES IN TWINS; FEMALE; HUMANS; IMMERSION; INCIDENCE; MIDDLE AGED; QUESTIONNAIRES; RAYNAUD DISEASE; SEVERITY OF ILLNESS INDEX; TWINS; TWINS, MONOZYGOTIC; VASOCONSTRICTION;

EID: 34247644383     PISSN: 21514658     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.22626     Document Type: Article

References (19)

1. Maricq HR, Carpentier PH, Weinrich MC, Keil JE, Franco A, Drouet P, et al. Geographic variation in the prevalence of Raynaud's phenomenon: Charleston, SC, USA, vs Tarentaise, Savoie, France. J Rheumatol 1993;20:70-6.
2. Susol E, MacGregor AJ, Barrett JH, Wilson H, Black C, Welsh K, et al. A two-stage, genome-wide screen for susceptibility loci in primary Raynaud's phenomenon. Arthritis Rheum 2000;43:1641-6.
3. Freedman RR, Mayes MD. Familial aggregation of primary Raynaud's disease. Arthritis Rheum 1996;39:1189-91.
4. Brennan P, Silman A, Black C, Bernstein R, Coppock J, Maddison P, et al, and the UK Scleroderma Study Group. Validity and reliability of three methods used in the diagnosis of Raynaud's phenomenon. Br J Rheumatol 1993;32:356-61.
5. Cherkas LF, Howell K, Carter L, Black CM, MacGregor AJ. The use of portable radiometry to assess Raynaud's phenomenon: a practical alternative to thermal imaging. Rheumatology (Oxford) 2001;40:1384-7.
6. Maricq HR, Weinrick MC. Diagnosis of Raynaud's phenomenon assisted by colour charts. J Rheumatol 1988;15:454-9.
7. Cherkas LF, Carter L, Spector TD, Howell KJ, Black CM, MacGregor AJ. Use of thermographic criteria to identify Raynaud's phenomenon in a population setting. J Rheumatol 2003;30:720-2.
8. Witte JS, Carlin JB, Hopper JL. Likelihood-based approach to estimating twin concordance for dichotomous traits. Genet Epidemiol 1999;16:290-304.
9. Neale MC, Cardon LR. Methodology for genetic studies of twins and families. Dordrecht (The Netherlands): Kluwer Academic; 1992.
10. Sham PC, Walters EE, Neale MC, Heath AC, MacLean CJ, Kendler KS. Logistic regression analysis of twin data: estimation of parameters of the multifactorial liability-threshold model. Behav Genet 1994;24:229-38.
11. Intercooled Stata for Windows. Version 8.0. College Station (TX): Statacorp; 2003.
12. Neale MC. Mx Software. Version 1.7.01. Richmond (VA): Department of Psychiatry, Virginia Commonwealth University; 2005.
13. DeFries JC, Fulker DW. Multiple regression analysis of twin data. Behav Genet 1985;15:467-73.
14. Herrick AL. Pathogenesis of Raynaud's phenomenon [review]. Rheumatology (Oxford) 2005;44:587-96.
15. Hellstrom HR. New evidence for the spasm-of-resistance-vessel concept of ischemic diseases [review]. Med Hypotheses 1999;53:200-9.
16. Smyth AE, Hughes AE, Bruce IN, Bell AL. A case-control study of candidate vasoactive mediator genes in primary Raynaud's phenomenon. Rheumatology (Oxford) 1999;38:1094-8.
17. Andrew T, Hart DJ, Sneider H, de Lange M, Spector TD, MacGregor AJ. Are twins and singletons comparable? A study of disease-related and lifestyle characteristics in adult women. Twin Res 2001;4:464-77.
18. Kyvik KO. Generalisability and assumptions of twin studies. In: Spector T, Snieder H, MacGregor AJ, editors. Advances in twin and sib-pair analysis. London: Greenwich Medical Media Ltd; 2000. p. 68-77.
19. Williams FM, Cherkas LF, Spector TD, MacGregor AJ. A common genetic factor underlies hypertension and other cardiovascular disorders. BMC Cardiovasc Disord 2004;4:20-7.