Investigation of low levels of plasma valproic acid concentration following simultaneous administration of sodium valproate and rizatriptan benzoate

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 3, 2007, Pages 383-386

  Hokama, Nobuo ^a   Hobara, Norio ^a   Kameya, Hiromasa ^a   Ohshiro, Susumu ^a   Hobara, Narumi ^b   Sakanashi, Matao ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCARBOXYLATE TRANSPORTER; RIZATRIPTAN; VALPROIC ACID; ANTICONVULSIVE AGENT; SEROTONIN AGONIST; TRIAZOLE DERIVATIVE; TRYPTAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG TRANSPORT; MALE; NONHUMAN; PARAMETER; RAT; ANIMAL; BLOOD; DRUG INTERACTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTICONVULSANTS; DRUG INTERACTIONS; MALE; MONOCARBOXYLIC ACID TRANSPORTERS; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN AGONISTS; TRIAZOLES; TRYPTAMINES; VALPROIC ACID;

EID: 34247640030     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.3.0007     Document Type: Article

References (15)

1. Brodie, B. B., Hogben, C. A. (1957) Some physico-chemical factors in drug action. J. Pharm. Pharmacol. 9: 345-380
2. Fudio, S., Carcas, A., Pinana, E., Ortega, R. (2006) Epileptic seizures caused by low valproic acid levels from an interaction with meropenem. J. Clin. Pharm. Ther. 31: 393-396
3. Gugler, R, von Unruh, G. E. (1980) Clinical pharmacokinetics of valproic acid. Clin. Pharmacokinet. 5: 67-83
4. Hobara, N., Hokama, N., Kameya, H., Ohshiro, S., Sakanashi, M. (1998a) Influence of meropenem, a new carbapenem antibiotic, on plasma carvedilol concentration following simultaneous administration of carvedilol and meropenem in rats. Kyushu Yakugaku Kaihou 52: 15-18 (in Japanese)
5. Hobara, N., Hokama, N., Kameya, H., Ohshiro, S., Sakanashi, M. (1998b) Influence of cefozopran, a new carbapenem antibiotic, on plasma carvedilol concentration following simultaneous administration of carvedilol and cefozopran in rats. Kyushu Yakugaku Kaihou 52: 9-13 (in Japanese)
6. Klotz, U., Antonin, K. H. (1997) Pharmacokinetics and bioavailability of sodium valproate. Clin. Pharmacol. Ther. 21: 736-743
7. Meunier, H., Carraz, G., Neunier, Y., Eymard, M., Aimard, M. (1963) Pharmacodynamic properties of N-dipropylacetic acid. Therapie 18: 435-438
8. Musson, D. G., Birk, K. L., Paneblanco, D. L., Gaghano, K. D., Rogers, J. D., Goldborg, M. R. (2001) Pharmacokinetics of rizatriptan in healthy elderly subjects. Int. J. Clin. Pharmacol. Ther. 39: 447-452
9. Ohshiro, S., Hobara, H., Sakai, M., Hokama, N., Kameya, H., Sakanashi, M. (2003) Effects of salicylate on the pharmacokinetics of valproic acid after oral administration of sodium valproate in rats. Biogenic Amines 17: 401-407
10. Shadle, C. R., Liu, G., Goldberg. M. R. (2000) A double-blind, placebo-controlled evaluation of the effect of oral doses of rizatriptan 10 mg on oral contraceptive pharmacokinetics in healthy female volunteers. J. Clin. Pharmacol. 40: 309-315
11. Tamai, I., Takanaga, H., Maeda, H., Sai, Y., Ogihara, T., Higashida, H., Tsuji, A. (1995) Participation of a proton-contransporter, MCT1, in the intestinal transport of monocarboxylic acids. Biochem. Biophys. Res. Commun. 214: 482-489
12. Tamai, I., Takanaga, H., Maeda, H., Yabuuchi, H., Sai, Y., Suzuki, Y., Tsuji, A. (1997) Intestinal brush-border membrane transport of monocarboxylic acids mediated by proton-coupled transport and anion transport mechanisms. J. Pharm. Pharmacol. 49: 108-112
13. Tsuji, A., Takanaga, H., Tamai, I., Terasaki, T. (1994) Transcellular transport of benzoic acid across Caco-2 cells by a pH-dependent and carrier-mediated transport mechanism. Pharm. Res. 11: 30-37
14. Utoguchi, N., Audus, K. L. (2000) Carrier-mediated transport of valproic acid in BeWo cells, a human trophoblast cell line. Int. J. Pharm. 195: 115-124
15. Vyas, K. P., Halpin, R. A., Geer, L. A., Ellis, J. D., Liu, L., Cheng, H., Chavez-Eng, C., Matuszewski, B. K., Varga, S. L., Guiblin, A. R., Rogers, J. D. (2000) Disposition and pharmacokinetics of the anti-migraine drug, rizatriptan, in humans. Drug Metab. Dispos. 28: 89-95