Clinicopathologic and immunohistochemistry characterization of synchronous multiple primary gastric adenocarcinoma

Journal of Gastrointestinal Surgery

Volumn 11, Issue 3, 2007, Pages 233-239

  Ribeiro Jr , Ulysses ^a   Jorge, Uana M ^a   Safatle Ribeiro, Adriana V ^a   Yagi, Osmar K ^a   Scapulatempo, Cristovam ^a   Perez, Rodrigo O ^a   Corbett, Carlos E P ^a   Alves, Venâncio A F ^a   Zilberstein, Bruno ^a   Gama Rodrigues, Joaquim ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

HMLH1; HMSH2; HMSH6; Immunohistochemistry; P53; Synchronous primary gastric adenocarcinoma

Indexed keywords

DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN MSH2; PROTEIN P53; SIGNAL TRANSDUCING ADAPTOR PROTEIN; UNCLASSIFIED DRUG;

ADENOCARCINOMA; AGED; ARTICLE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; MULTIPLE CANCER; PATHOLOGY; STOMACH TUMOR;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOCARCINOMA; AGED; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NEOPLASMS, MULTIPLE PRIMARY; NUCLEAR PROTEINS; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34247638512     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11605-007-0101-7     Document Type: Article

References (34)

1. Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol 2006;12:354-362.
2. Honmyio U, Misumi A, Murakami A, Hagan Y, Akagi M. Clinicopathological analysis of synchronous multiple gastric carcinoma. Eur J Surg Oncol 1989;15:316-321.
3. Marrano D, Viti G, Grigioni W, Marra A. Synchronous and metachronous cancer of the stomach. Eur J Surg Oncol I987;6:493-498.
4. Kodera Y, Yamamura Y, Torii A, Uesaka K, Iría T, Yasui K. Incidence, diagnosis and significance of multiple gastric cancer. Br J Surg 1995;82:1540-1543.
5. Wittekind C, Klimpfinger M, Hermanek P, Tannapfel A. Multiple simultaneous gastric carcinomas. Br J Cancer 1997;76:1604-1609.
6. Lee H, Lee BL, Kim SH, Woo DK, Kim HS, Kim WH. Microsatellite instability in synchronous gastric carcinomas. Int J Cancer 2001;91:619-624.
7. Kaibara N, Maeta M, Ikeguchi M. Patients with multiple primary gastric cancers tend to develop second primaries in organs other than the stomach. Surg Today 1993;23:186-188.
8. Parry DM, Mulvihill JJ, Miller RW, Berg K, Carter CL, Strategies for controlling cancer through genetics. Cancer Res 1988;47:6814-6817.
9. Perucho M. Microsatellite instability: the mutator that mutates the other mutator, Nat Med 1996;2:630-631.
10. Moertel CG, Bargen JA, Soule EH. Multiple gastric cancers. Review of the Literature and study of 42 cases. Gastroenterology 1957;32:1095-1103.
11. Ribeiro U Jr, Finkelstein SD, Safatle-Ribeiro AV, Landreneau RJ, Clarke MR, Bakker A, Swalsky PA, Gooding WE, Posner MC. p53 sequence analysis predicts treatment response and outcome of patients with esophageal carcinoma. Cancer 1998;83:7-18.
12. Kang GH, Yoon OS, Lee HK, Kwon YM, Ro JY. Clinicopathologic characteristics of replication error-positive gastric carcinoma. Mod Pathol 1999;12:15-20.
13. Fiocca R, Luinetti O, Villani L, Mastracci L, Quilici P, Grillo F, Ranzani ON. Molecular mechanisms involved in the pathogenesis of gastric carcinoma: interactions between genetic alterations, cellular phenotype and cancer histotype. Hepatogastroenterology 2001;48:1523-1530.
14. Dietmaier W, Wallinger S, Blocker T, Kullmann F, Fishel R, Ruschoff J. Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res 1997;57:4749-4756.
15. Kim WH, Lee HW, Park SH, Kim YI, Chi JG, Microsatellite instability in young age colorectal cancer. Pathol Int 1998;48:586-594.
16. Chong JM, Fukayama M, Hayashi Y, Takizawa T, Koike M, Konishi M, Kikuchi R-Y, Miyaki M. Microsatellite instability in the progression of gastric carcinoma. Cancer Res 1994;54:4595-4597.
17. Semba S, Yokozaki H, Yamamoto S, et al. Microsatellite instability in precancerous lesions and adenocarcinomas of the stomach. Cancer 1996;77:1620-1627.
18. Santos NR, Seruca R, Constancia M, Seixas M, Simões MS. Microsatellite instability at multiple loci in gastric carcinoma: clinicopathologic implications and prognosis. Gastroenterology 1996;110:38-44.
19. Perez RO, Jacob CE, D'Otaviano FL, Alvarenga C, Safatle-Ribeiro A, Ribeiro U Jr, Bresciani C, Zilberstein B, Krieger JE, Habr-Gama A, Gama-Rodrigues J. Microsatellite instability in solitary and sporadic gastric cancer. Rev Hosp Clin Fac Med São Paulo 2004;59:279-285.
20. Nakashima H, Honda M, Inoue H, Shibuta K, Arinaga S, Era S, Ueo H, Mon M, Akiyoshi T. Microsatellite instability in multiple gastric cancers. Int J Cancer 1995;64:239-242.
21. Chung YJ, Song JM, Lee JY, Jung YT, Seo EJ, Choi SW, Rhyu MG. Microsatellite instability-associated mutations associate preferentially with the intestinal type of primary gastric carcinomas in a high-risk population. Cancer Res 1996;56:4662-4665.
22. Yamasita K, Arimura Y, Kurokawa S, et al. Microsatellite instability in patients with multiple primary cancers of the gastrointestinal tract. Gut 2000;46:790-794.
23. Miyoshi E, Haruma K, Hiyama T, Tanaka S, Yoshihara M, Shimamoto F, Chayama K. Microsatellite instability is a genetic marker for the development of multiple gastric cancers. Int J Cancer (Pred Oncol) 2001;95:350-353.
24. Fleisher AS, Esteller M, Wang S, Tamura G, Suzuki H, Yin J, Zou TT, Abraham JM, Kong D, Smolinski KN, Shi YQ, Rhyu MG, Powell SM, James SP, Wilson KT, Herman JG, Meltzer SJ. Hypermethylation of the hMLHI gene promoter in human gastric cancers with microsatellite instability. Cancer Res 1999;59(5):1090- 1095.
25. Sakata K, Tamura G, Endoh Y, Ohmura K, Ogata S, Motoyama T. Hypermethilation of the hMLH1 gene promoter in solitary and multiple gastric cancers with microsatellite instability. Br J Cancer 2002;86:564-567.
26. Jung H, Jung K, Shin Y, Ro J, Kang G. Methilation of the hMLH1 promoter in multiple gastric carcinomas with microsatellite instability. Pathol Int 2001;51:445-451.
27. Leung SY, Yuen ST, Chung LP, Chu KM, Cham AS, Ho JC. hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability. Cancer Res 1999;59:159-164.
28. Bevilacqua RA, Simpson AJ. Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability. Int J Cancer 2000;87:200-203.
29. Kang GH, Kim CJ, Kim WH, Kang YK, Kim HO, Kim YI. Genetic evidence for the multicentric origin of synchronous gastric carcinoma. Lab Invest 1997;76:407-417.
30. Pedroni M, Tammassia MG, Percesepe A, Roncucci L, Benatti P, Lanza G, et al. Microsatellite instability in multiple colorectal tumors. Int J Cancer 1999;81:1-5.
31. Park IJ, Kim HC, Kim JS, Yu ES, Chang SY, Kim JC. Correlation between hMLH1/hMSH2 and p53 protein expression in sporadic colorectal cancer. Hepatogastroenterology 2005;52:450-454.
32. Ogata S, Tamura G, Endoh Y, Sakata K, Ohmura K, Motoyama T. Microsatellite alterations and target gene mutations in the early stages of multiple gastric cancer. J Pathol 2001;194:334-340.
33. Iacopetta BJ, Soong R, House AK, Hamelin R. Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-ß type II receptor, IGFII receptor, and Bax genes. J Pathol 1999;187:428-432.
34. Endoh Y, Sakata K, Tamura G, Ohmura K, Ajioka Y, Watanabe H, Motoyama T. Cellular phenotypes of differentiated-type adeno-carcinomas and precancerous lesions of the stomach are dependent on the genetic pathways. J Pathol 2000;191:257-263.