Association between mild renal dysfunction and insulin resistance or metabolic syndrome in a random nondiabetic population sample

Kidney and Blood Pressure Research

Volumn 30, Issue 2, 2007, Pages 88-96

  Onat, Altan ^a,b,g   Hergenç, Gülay ^c   Uyarel, Hüseyin ^d   Özhan, Hakan ^f   Esen, A Metin ^e   Karabulut, Ahmet ^d   Albayrak, Sinan ^f   Can, Günay ^b   Keleş, Ibrahim ^b  

^a Turkish Society of Cardiology   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c YILDIZ TECHNICAL UNIVERSITY   (Turkey)

^d DR SIYAMI ERSEK THORACIC AND CARDIOVASCULAR SURGERY TRAINING AND RESEARCH HOSPITAL   (Turkey)

^e Kosuyolu Heart Center   (Turkey)

^f ABANT IZZET BAYSAL UNIVERSITY   (Turkey)

^g NONE   (Turkey)

Author keywords

Dyslipidemia; Glomerular filtration rate; Insulin resistance; Kidney dysfunction; Metabolic syndrome

Indexed keywords

CREATININE;

ADULT; AGE DISTRIBUTION; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; COVARIANCE; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GLOMERULUS FILTRATION RATE; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; KIDNEY DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MODEL; PATIENT SELECTION; PRIORITY JOURNAL; RANDOMIZATION;

ADULT; C-REACTIVE PROTEIN; COHORT STUDIES; CREATININE; CROSS-SECTIONAL STUDIES; FEMALE; GLOMERULAR FILTRATION RATE; HOMEOSTASIS; HUMANS; INSULIN RESISTANCE; KIDNEY; KIDNEY DISEASES; LINEAR MODELS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; SEX CHARACTERISTICS; TURKEY;

EID: 34247626158     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000100487     Document Type: Article

References (29)

1. Foley RN, Wang C, Collins AJ: Cardiovascular risk factor profiles and kidney function stage in the US general population: the NHANES III study. Mayo Clin Proc 2005;80:1270-1277.
2. Culleton BF, Larson MG, Wilson PW, Evans JC, Parfrey PS, Levy D: Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney Int 1999;56:2214-2219.
3. Weiner DE, Tighiouart H, Amin MG, et al: Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol 2004;16:1307-1315.
4. Chen J, Muntner P, Hamm LL, et al: The metabolic syndrome and chronic kidney disease in US adults. Ann Intern Med 2004;140:167-174.
5. National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis 2002;39(suppl 1):S1-S266.
6. Rigalleau V, Lasseur C, Perlemoine C, et al: Estimation of glomerular filtration rate in diabetic subjects. Cockcroft formula or modification of Diet in Renal Disease study equation? Diabetes Care 2005;28:838-843.
7. Rule AD, Larson TS, Bergstralh EJ, Slezak JM, Jacobsen SJ, Cosio FG: Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med 2004;141:929-937.
8. Kubo M, Kiyohara Y, Kato I, et al: Effect of hyperinsulinemia on renal function in a general Japanese population: the Hisayama study. Kidney Int 1999;55:2450-2456.
9. Chen J, Muntner P, Hamm LL, Fonseca V, Batuman V, Whelton PK, He J: Insulin resistance and risk of chronic kidney disease in nondiabetic US adults. J Am Soc Nephrol 2003;14:469-477.
10. Fox CS, Larson MG, Leip EP, Meigs JB, Wilson PWF, Levy D: Glycemic status and development of kidney disease. Diabetes Care 2005;28:2436-2440.
11. Onat A, Ceyhan K, Ba?ar Ö, Erer B, Toprak S, Sansoy V: Metabolic syndrome: major impact on coronary risk in a population with low cholesterol levels - a prospective and cross-sectional evaluation. Atherosclerosis 2002;165:285-292.
12. Onat A. Risk factors and cardiovascular disease in Turkey. Atherosclerosis 2001;156:1-10.
13. Onat A, Avci GŞ, Şenocak M, Örnek E, Gözükara Y: Plasma lipids and their interrelation in Turkish adults. J Epidem Commun Health 1992;46:470-476.
14. Genuth S, Alberti KG, Bennett P, et al; Expert Committee on the Diagnosis and Classification of Diabetes Mellitus: Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 2003;26:3160-3167.
15. Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486-2497.
16. Onat A, Hergenç G, Türkmen S, Yazici M, Sari İ, Can G: Discordance between insulin resistance and metabolic syndrome: features and associated cardiovascular risk in adults with normal glucose regulation. Metabolism 2006;55:445-452.
17. Mather KJ, Hunt AE, Steinber HO, et al: Repeatability characteristics of simple indices of insulin resistance: implications for research applications. J Clin Endocrinol Metab 2001;86:5457-5464.
18. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D: A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999;130:461-470.
19. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density-lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502.
20. Muntner P, He J, Astor BC, Folsom AR, Coresh J: Traditional and nontraditional risk factors predict coronary heart disease in chronic kidney disease: results from the Atherosclerosis Risk in Communities Study. J Am Soc Nephrol 2005;16;529-538.
21. Wannamethee SG, Shaper AG, Lowe GDO, Lennon L, Rumley A, Whincup PH: Renal function and cardiovascular mortality in elderly men: the role of inflammatory, procoagulant, and endothelial biomarkers. Eur Heart J 2006;27:2975-2981.
22. Egan BM, Papademetriou V, Wofford M, Calhoun D, Fernandes J, Riehle JE, Nesbitt S, Michelson E, Julius S: Metabolic syndrome and insulin resistance in the TROPHY substudy: contrasting views in patients with high-normal blood pressure. Am J Hypertens 2005;18;3-12.
23. Fliser D, Pacini G, Engelleiter R, et al:. Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease. Kidney Int 1998;53:1343-1347.
24. Stuweling EM, Hillege HL, Bakker SJ, Gans RO, De Jong PE, de Zeeuw D: C-reactive protein is associated with renal function abnormalities in a nondiabetic population. Kidney Int 2003;63:654-661.
25. Stam F, van Guldner C, Becker A, Dekker JM, Heine RJ, Bouter LM, Stehouwer CDA: Endothelial dysfunction contributes to renal function-associated cardiovascular mortality in a population with mild renal insufficiency: the Hoorn Study. J Am Soc Nephrol 2006;17:537-545.
26. Onat A, Can G, Hergenç G, Yazici M, Karabulut A, Albayrak S: Serum apolipoprotein B predicts dyslipidemia, metabolic syndrome and, in women, hypertension, diabetes, independent of markers of central obesity and inflammation. Int J Obes 2007, doi:10.1038/sj.ijo.0803552.
27. Muntner P, Coresh J, Smith JC, Eckfeldt J, Klag MJ: Plasma lipids and risk of developing renal dysfunction: the Atherosclerosis Risk in Communities study. Kidney Int 2000;58:293-301.
28. Onat A, Hergenç G, Uyarel H, Can G, Özhan H: Prevalence, incidence, predictors and outcome of type 2 diabetes in Turkey. Anadolu Kardiyol Derg 2006;6:314-321.
29. Mahley RW, Pepin J, Palaoǧlu KE, Malloy MJ, Kane JP, Bersot TP: Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase: high density lipoprotein characterization and gender-specific effects of apolipoprotein E genotype. J lipid Res 2000;41:1290-1301.