The NADH fluorescence/UV reflectance ratio provides a semi-quantitative measure for NADH fluorometry of blood perfused rat heart

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 2927, Issue , 1996, Pages 180-191

  Coremans, J M C C ^a   Ince, C ^b   Bruining, Hajo A ^a   Puppels, Gerwin J ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CHARGE COUPLED DEVICES; FLUORESCENCE; IMAGING SYSTEMS; IMAGING TECHNIQUES; REFLECTION;

ABSORBANCE; BIPRISM; CCD VIDEO CAMERAS; CORRECTION PROCEDURES; FLUORIMETRY; IN-VIVO; METABOLIC STATES; MOVEMENT ARTIFACTS; NADH FLUORESCENCES; NON-INVASIVE MONITORING; QUANTITATIVE MEASURES; RAT HEARTS; REFLECTANCE IMAGES; REFLECTANCE RATIOS; SEMI-QUANTITATIVE ANALYSES; SIMULTANEOUS MEASUREMENTS; THICK SAMPLES; TISSUE PHANTOMS; UV EXCITATIONS;

TISSUE;

EID: 34247623979     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.260640     Document Type: Conference Paper

References (36)

1. Chance, B. and B. Thorell. 1959. Localization and kinetics of reduced pyridine nucleotides in living cells by microfluorometry. J. Biol. Chem. 234:3044-3050.
2. Duboc, D., M. Toussaint, D. Donsez, S. Weber, F. Guerin, M. Degeorges, G. Renault, J. Poliansky and J.J. Pocidalo. 1986. Detection of regional myocardial ischaemia by NADH laser fluorimetry during human left heart catheterisation. Lancet 2(8505):522.
3. Duboc, D., G. Renault, J. Poliansky, M. Muffat-Joly, M. Toussaint, F. Guenn, J.J. Pocidalo and M. Fardeau. 1987. NADH measured by laser fluorimetry in skeletal muscle in McArdle's disease. N. Eng. J. Med. 316:1664-1665.
4. Renault, G., E. Raynal, M. Sinet, M. Muffat-Joly, J.-P. Berthier, J. Cornillault, B. Godard and J.-J. Pocidalo. 1984. In situ double-beam NADH laser fluorimetry: a choice of a reference wavelength. Am. J. Physiol. 246:H491-H499.
5. Austin, G., R. Jutzy, B. Chance and C. Barlow. 1978. Noninvasive monitoring of human brain oxidative metabolism. In Frontiers of Biological Energetics. D.L. Dutton, J.S. Leigh, and A. Scapa, editors. Academic Press, New York. 1445-1455.
6. Ince, C., J.M.C.C. Coremans and H.A. Bruining. 1992. In vivo NADH fluorescence. Adv. Exp. Med. Biol. 317:277-296.
7. Dóra, E., L. Gyulai and A.G.B. Kovách. 1984. Determinants of brain activation-induced cortical NAD/NADH responses in vivo. Brain Res. 299:61-72.
8. Harbig, K, B. Chance, A.G.B. Kovách and M. Reivich. 1976. In vivo measurement of pyridine nucleotide fluorescence from cat brain cortex. J. Appl. Physiol. 41:480-488.
9. Ji, S., B. Chance, B.H. Stuart and R. Nathan. 1977. Two dimensional analysis of the redox state of the rat cerebral cortex in vivo by NADH fluorescence photography. Brain Res. 119:357-373.
10. Ji, S., B. Chance, K. Nishiki, T. Smith and T. Rich. 1979. Micro-light guides: a new method for measuring tissue fluorescence and reflectance. Am. J. Physiol. 236(3):C144-C156.
11. Jöbsis, F.F., M. O'Connor, A. Vitale and H. Vreman. 1971. Intracellular redox changes in functioning cerebral cortex. I. Metabolic effects of epileptiform activity. J. Neurophysiol. 34:735-749.
12. Kobayashi, S., K. Nishiki, K. Kaede and E. Ogata. 1971. Optical consequences of blood substitution on tissue oxidation-reduction state fluorometry. J. Appl. Physiol. 3l(1):93-96.
13. Mayevsky, A., and B. Chance. 1974. Repetitive patterns of metabolic changes during cortical spreading depression of the awake rat. Brain Res. 65:529-533.
14. Mayevsky, A., and B. Chance. 1982. Intracellular oxidation-reduction state measured in situ by a multichannel fiber-optic surface fluorometer. Science 217:537-540.
15. Mayevsky, A., S. Nioka and B. Chance. 1987. Fiber optic surface fluorometry/reflectometry and 31-P-NMR for monitoring the intracellular energy state in vivo. Adv. Exp. Med. Biol. 222:365-374.
16. Mills, S.A., F.F. Jöbsis and A.V. Seaber. 1977. A fluorometric study of oxidative metabolism in the in vivo canine heart during acute ischemia and hypoxia. Ann. Surgery 186:193-200.
17. Osbakken, M.D. 1994. I-2 Metabolic regulation of in vivo myocardial contractile function: multiparameter analysis. Mol. and Cell. Biochem. 133/134:13-37.
18. Heineman, F.W., and R.S. Balaban. 1990. Effects of afterload and heart rate on NAD(P)H redox state in the isolated rabbit heart. Am. J. Physiol. 264:H433-H440.
19. Koretsky, A.P., L.A. Katz and R.S. Balaban. 1987. Determination of pyridine nucleotide fluorescence from the perfused heart using an internal standard. Am. J. Physiol. 253:H856-H862.
20. Kramer, R.S., and R.D. Pearlstein. 1979. Cerebral cortical microfluorimetry at isosbestic wavelengths for correction of vascular artifact. Science 205:693-696.
21. Vern, B., W.C. Whitehouse and W.H. Schuette. 1975. Sodium fluorescein: a new reference for NADH fluorometry. Brain Res. 98:405-409.
22. Ince, C., and H.A. Bruining. 1991. Optical Spectroscopy for the measurement of tissue hypoxia. In Update in Intensive Care and Emergency Medicine: Update 1991. J.L. Vincent, editor. Springer-Verlag, Germany. 161-171.
23. Coremans, J.M.C.C., C. Ince, H.A. Bruining and G.J. Puppels. 1996. Semi-quantitative analysis of NADH fluorescence images of rat heart. submitted.
24. Coremans, J.M.C.C., C. Ince and H.A. Bruining. 1993. NADH fluorimetry and diffuse reflectance spectroscopy on rat heart. In Medical Optical Tomography: Functional imaging and monitoring. G. Müller, B. Chance, R. Alfano, S. Arridge, J. Beuthan, E. Gratton, M. Kaschke, B. Masters, S. Svanberg and P. van der Zee, editors. SPIE Optical Engineering Press, Washington USA. Vol. IS 11:589-617.
25. Ploem, J.S. 1970. Standards for fluorescence microscopy. In Standardization in Immunofluorescence. E.J. Holborow editor. Blackwell, Oxford, UK. 137-153.
26. Flock, S.T., S.L. Jacques, B.C. Wilson, W.M. Star and M.J.C van Gemert. 1992. Optical properties of Intralipid: A phantom medium for light propagation studies. Lasers in Surg. and Med. 12:510-519.
27. Staveren, H.J. van, C.J.M. Moes, S.A. Prahl, and M.J.C. van Gemert. 1991. Light scattering of Intralipid 10% in the wavelength range of 400-1100 nm. Appl. Opt. 30(31):4507-4514.
28. Eisinger, J., and J. Flores. 1979. Front-face fluorometry of liquid samples. Anal. Biochem. 94:15-21.
29. Kubelka, P. 1948. New contributions to the optics of intensily light-scattering materials. Part I. J. Opt. Soc. Amer. 38(5):448-457.
30. Kubelka, P. 1954. New contributions to the optics of intensily light-scattering materials. Part II: Nonhomogeneous layers. J. Opt. Soc. Amer. 44(4):330-335.
31. Kessler, M., and K. Frank. 1992. The Erlangen micro-lightguide spectrophotometer EMPHO 1. In Quantitative Spectroscopy in Tissue. K. Frank and M. Kessler, editors. pmi Verl., Frankfurt am Main, Germany. 61-74.
32. Heinrich, U., J. Hoffmann and D.W. Lübbers. 1987. Quantitative evaluation of optical reflection spectra of blood-free perfused guinea pig brain using a nonlinear multicomponent analysis. Pflügers Arch. 409:152-157.
33. Ince, C., J.F. Ashruf, J.A.M. Avontuur, P.A. Wieringa, J.A.E. Spaan and H.A. Bruining. 1993. Heterogeneity of the hypoxic state in the rat heart is determined at capillary level. Am. J. Physiol. 264:H294-H301.
34. Steenbergen, C., G. de Leeuw, C. Barlow, B. Chance and J.R. Williamson. 1977. Heterogeneity of the hypoxic state in perfused rat heart. Circ. Res. 41:606-615.
35. Williamson, J.R., K.N. Davis and G. Medina-Ramirez. 1982. Quantitative analysis of heterogeneous NADH fluorescence in perfused rat hearts during hypoxia and ischemia. J. Mol. and Cell. Cardiol. 14(suppl. 3):29-35.
36. Brandes, R., V.M. Figueredo, S.A. Camacho, B.M. Massie and M.W. Weiner. 1992. Suppression of motion artifacts in fluorescence spectroscopy of perfused hearts. Am. J. Physiol. 263:H972-H980.