Glucoamylase gene, vldI, is linked to validamycin biosynthesis in Streptomyces hygroscopicus var. limoneus, and vldADEFG confers validamycin production in Streptomyces lividans, revealing the role of VldE in glucose attachment

Gene

Volumn 395, Issue 1-2, 2007, Pages 151-159

  Singh, Deepak ^a   Kwon, Hyung Jin ^a   Rajkarnikar, Arishma ^a   Suh, Joo Won ^a  

^a Myong Ji University   (South Korea)

Author keywords

Gene inactivation; Heterologous expression; Promoter probe assay; Streptomyces; Validamycin biosynthesis

Indexed keywords

GLUCAN 1,4 ALPHA GLUCOSIDASE; UNCLASSIFIED DRUG; VALIDAMYCIN; VALIDAMYCIN A; VALIDAMYCIN B; VALIDAMYCIN DERIVATIVE; VALIDAMYCIN F; VALIDAMYCIN H;

ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; GENE SEQUENCE; GENE STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; STREPTOMYCES HYGROSCOPICUS; STREPTOMYCES LIVIDANS;

BASE SEQUENCE; CHROMOSOME MAPPING; DNA PRIMERS; DNA, BACTERIAL; ESCHERICHIA COLI; GENES, BACTERIAL; GLUCAN 1,4-ALPHA-GLUCOSIDASE; GLUCOSE; INOSITOL; KINETICS; MODELS, BIOLOGICAL; MULTIGENE FAMILY; PLASMIDS; RECOMBINANT PROTEINS; STREPTOMYCES; STREPTOMYCES LIVIDANS;

STREPTOMYCES; STREPTOMYCES HYGROSCOPICUS; STREPTOMYCES LIVIDANS;

EID: 34247620686     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.02.015     Document Type: Article

References (21)

1. Asano N., Yamaguchi T., Kameda Y., and Matsui K. Effect of validamycins on glycohydrolases of Rhizotonia solani. J. Antibiot. 40 (1987) 526-532
2. Bai L., et al. Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A. Chem. Biol. 13 (2006) 387-397
3. Bierman N., Logan R., O'Brien K., Seno E.T., Rao R.N., and Schoner B.E. Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene 116 (1992) 43-49
4. Clayton T.M., and Bibb M.J. Streptomyces promoter-probe plasmids that utilize the xylE gene of Pseudomonas putida. Nucleic Acids Res. 18 (1990) 1077
5. Denis F., and Brezinnski R. An improved aminoglycoside resistance gene cassette for use in gram-negative bacteria and Streptomyces. FEMS Microbiol. Lett. 65 (1991) 261-264
6. Dong H., Mahmud T., Tornus I., Lee S., and Floss H.G. Biosynthesis of the validamycins: identification of intermediates in the biosynthesis of validamycin A by Streptomyces hygroscopicus var. limoneus. J. Am. Chem. Soc. 123 (2001) 2733-2742
7. Gibson R.P., Turkenburg J.P., Charnock S.J., Lloyd R., and Davies G.J. Insights into trehalose synthesis provided by structure of the retaining glucosyltransferase OtsA. Chem. Biol. 9 (2002) 1337-1346
8. Horii S., Kameda Y., and Kawahara K. Studies on validamycins, new antibiotics. VIII. Isolation and characterization of validamycins, C, D, E and F. J. Antibiot. 25 (1972) 48-53
9. Ingram C., Brawner M., Youngman P., and Westpheling J. xylE functions as an efficient reporter gene in Streptomyces spp.: use for the study of galP1, a catabolite-controlled promoter. J. Bacteriol. 171 (1989) 6617-6624
10. Iwasa T., Yamamoto H., and Shibata M. Studies on validamycins, new antibiotics. I. Streptomyces hygroscopicus var. limoneus nov. var., validamycin-producing organism. J. Antibiot. 23 (1970) 595-602
11. Iwasa T., Higashide E., Yamamoto H., and Shibata M. Validamycins, new antibiotics. II. Production and biological properties of validamycins A and B. J. Antibiot. 24 (1971) 107-113
12. Kameda Y., Horii S., and Yamano T. Microbial transformation of validamycins. J. Antibiot. 28 (1975) 298-306
13. Kameda Y., Asano N., Yamaguchi T., and Matsui K. Validoxylamines as trehalase inhibitors. J. Antibiot. 40 (1987) 563-564
14. Kieser T., Bibb M.J., Chater K.F., and Hopwood D.A. Practical Streptomyces Genetics (2000), John Innes Foundation, Norwich, United Kingdom
15. Nioh T., and Mizushima S. Effect of validamycin on the growth and morphology of Pellicularia saskii. J. Gen. Appl. Microbiol. 20 (1974) 373-383
16. Robson G.D., Kuhn P.J., and Trinci A.P. Effects of validamycin A on the morphology, growth and sporulation of Rhizoctonia cerealis, Fusarium culmorum and other fungi. J. Gen. Microbiol. 134 (1998) 3187-3194
17. Seo M.J., et al. Characterization of d-glucose α-1-phosphate uridylyltrasnferase (VldB) and glucokinase (VldC) involved in validamycin biosynthesis of Streptomyces hygroscopicus var. limoneus KCCM11405. J. Microbiol. Biotechnol. 16 (2006) 1311-1315
18. Singh D., et al. Genetic localization and heterologous expression of validamycin biosynthetic gene cluster isolated from Streptomyces hygroscopicus var. limoneus KCCM 11405 (IFO 12704). Gene 376 (2006) 13-23
19. Vara J., Lewandowska-Skarbek M., Wang Y.G., Donadio S., and Hutchinson C.R. Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Scachharopolyspora erythea (Streptomyces erythreus). J. Bacteriol. 171 (1989) 5872-5881
20. Yu Y., et al. Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008. Appl. Environ. Microbiol. 71 (2005) 5066-5076
21. Zhang C.S., et al. Biosynthesis of the C7-cyclitol moiety of acarbose in Actinoplanes species SE50/110. J. Biol. Chem. 277 (2002) 22853-22862