Protective effect of a phenolic-rich fraction from Schisandra chinensis against H2O2-induced apoptosis in SH-SY5Y cells

Journal of Pharmacy and Pharmacology

Volumn 59, Issue 3, 2007, Pages 455-462

  Jung, Chang Hwa ^a   Hong, Myung Hee ^a   Kim, Ji Hye ^a   Lee, Ji Yun ^a   Ko, Seong Gyu ^a   Cho, Kiho ^a   Seog, Ho Moon ^b  

^a Kyung Hee University   (South Korea)

^b Korea Food Research Institute   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GOMISIN; GOMISIN A; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHENOL; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; SCHISANDRA CHINENSIS EXTRACT; SCHISANDRIN; UNCLASSIFIED DRUG; ALCOHOL; NEUROPROTECTIVE AGENT; PHENOL DERIVATIVE; PLANT EXTRACT;

APOPTOSIS; ARTICLE; CELL VIABILITY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; INCUBATION TIME; NEUROBLASTOMA CELL; NEUROPROTECTION; OXIDATIVE STRESS; PROTEIN EXPRESSION; CHEMISTRY; DEGENERATIVE DISEASE; FRUIT; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHYTOTHERAPY; SCHISANDRACEAE; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; ETHANOL; FLOW CYTOMETRY; FRUIT; HUMANS; MASS SPECTROMETRY; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SCHISANDRA;

EID: 34247619389     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.59.3.0016     Document Type: Article

References (35)

1. Altiok, N., Ersoz, M., Karpuz, V., Koyuturk, M. (2006) Ginkgo biloba extract regulates differentially the cell death induced by hydrogen peroxide and simvastatin. Neurotoxicolology 27: 158-163
2. Behl, C., Davis, J. B., Lesley, R., Schubert, D. (1994) Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77: 817-827
3. Chen, D. F., Zhang, S. X., Xie, L., Xie, J. X., Chen, K., Kashiwada, Y., Zhou, B. N., Wang, P., Cosentino, L. M., Lee, K. H. (1997) Anti-aids agents - XXVI. Structure-activity correlations of Gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg. Med. Chem. 5: 1715-1723
4. Chen, D. F., Zhang, S. X., Kozuka, M., Sun, Q. Z., Feng, J., Wang, Q., Mukainaka, T., Nobukuni, Y., Tokuda, H., Nishino, H., Wang, H. K., Morris-Natschke, S. L., Lee, K. H. (2002) Interiotherins C and D, two new lignans from Kadsura interior and antitumor-promoting effects of related neolignans on Epstein-Barr virus activation. J. Nat. Prod. 65: 1242-1245
5. Chiu, P. Y., Mak, D. H., Poon, M. K., Ko, K. M. (2002) In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin. Planta Med. 68: 951-956
6. Fenton, H. J. H. (1984) Oxidation of tartaric acid in the presence of iron. J. Chem. Soc. 65: 899-910
7. Ferretti, G., Bacchetti, T., Moroni, C., Vignini, A., Curatola, G. (2003) Copper-induced oxidative damage on astrocytes: protective effect exerted by human high density lipoproteins. Biochim. Biophys. Acta 1635: 48-54
8. Green, D. R., Reed, J. C. (1998) Mitochondria and apoptosis. Science 281: 1309-1312
9. Guo, S., Bezard, E., Zhao, B. (2005) Protective effect of green tea polyphenols on the SH-SY5Y cells against 9-OHDA induced apoptosis through ROS-NO pathway. Free Radic. Biol. Med. 39: 682-695
10. Halliwell, B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59: 1609-1623
11. Hancke, J. L., Burgos, R. A., Ahumada, F. (1999) Schisandra chinensis (Turcz.) Baill. Fitoterapia 70: 451-471
12. He, X. G., Lian, L. Z., Lin, L. Z. (1997) Analysis of lignan constituents from Schisandra chinensis by liquid chromatography-electrospray mass spectrometry. J. Chromatogr A 757: 81-87
13. 2 in vitro. Brain Res. 671: 181-186
14. Ikeya, Y., Miki, E., Okada, M., Mitsuhashi, H., Chai, J. G. (1990) Benzoylgomisin Q and benzoylgomisin P, two new lignans from Schisandra sphenanthera Rehd. et Wils. Chem. Pharm. Bull. 38: 1408-1411
15. Ikeya, Y., Taguchi, H., Yosioka, I., Kobayashi, H. (1979) The constituents of Schizandra chinensis Baill. I. Isolation and structure determination of five new lignans, Gomisin A, B, C, F, and G, and the absolute structure of schizandrin. Chem. Pharm. Bull. 27: 1383-1394
16. Ishige, K., Schubert, D., Sagara, Y. (2001) Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radic. Biol. Med. 30: 433-446
17. Kang, S. S., Lee, J. Y., Choi, Y. K., Kim, G. S., Han, B. H. (2004) Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells. Bioorg. Med. Chem. Lett. 14: 2261-2264
18. Kim, D. H., Hung, T. M., Bae, K. H., Jung, J. W., Lee, S., Yoon, B. H., Cheong, J. H., Ko, K. H., Ryu, J. H. (2006) Gomisin A improves scopolamine-induced memory impairment in mice. Eur. J. Pharmacol. 542: 129-135
19. Liu, Z., Tao, X., Zhang, C., Lu, Y., Wei, D. (2005) Protective effects of hyperoside (quercetin-3-o-galactoside) to PC12 cells against cytotoxicity induced by hydrogen peroxide and tert-butyl hydroperoxide. Biomed. Pharmacother. 59: 481-490
20. Lu, H., Liu, G. (1992) Anti-oxidant activity of dibenzocyclooctene lignans isolated from Schisandraceae. Planta Med. 58: 311-313
21. Lu, H., Liu, W. (2006) P4-240: γ-schisandrin inhibits expression of amyloid β-peptide in M146L cell. Alzheimer's Dementia 2: S587
22. Lu, Z., Nie, G., Belton, P. S., Tang, H., Zhao, B. (2006) Structure-activity relationship analysis of antioxidant ability and neuroprotective effect of gallic acid derivatives. Neurochem. Int. 48: 263-274
23. Makino, N., Mochizuki, Y., Bannai, S., Sugita, Y. (1994) Kinetic studies on the removal of extracellular hydrogen peroxide by cultured fibroblasts. J. Biol. Chem. 269: 1020-1025
24. Nomura, M., Nakachiyama, M., Hida, T., Ohtaki, Y., Sudo, K., Aizawa, T., Aburada, M., Miyamoto, K. I. (1994) Gomisin A, a lignan component of Schizandora fruits, inhibits development of preneoplastic lesions in rat liver by 3′-methyl-4-dimethylaminoazobenzene. Cancer Lett. 76: 11-18
25. Ohtaki, Y., Hida, T., Hiramatsu, K., Kanitani, M., Ohshima, T., Nomura, M., Wakita, H., Aburada, M., Miyamoto, K. I. (1996) Deoxycholic acid as an endogenous risk factor for hepatocarcinogenesis and effects of gomisin A, a lignan component of Schizandra fruits. Anticancer Res. 16: 751-755
26. Ou, M. (1992) China-English manual of common-used in traditional Chinese medicine. Guangdong Science and Technology Press, Guangzhou, pp 69-70
27. Oyama, Y., Hayashi, A., Ueha, T., Maekawa, K. (1994) Characterization of 2′,7′-dichlorofluorescin fluorescence in dissociated mammalian brain neurons: estimation on intracellular content of hydrogen peroxide. Brain Res. 635: 113-117
28. Satoh, T., Sakai, N., Enokido, Y., Uchiyama, Y., Hatanaka, H. (1996) Free radical-independent protection by nerve growth factor and Bcl-2 of PC12 cells from hydrogen peroxide-triggered apoptosis. J. Biochem. 120: 540-546
29. Simonian, N. A., Coyle, J. T. (1996) Oxidative stress in neurodegenerative disease. Annu. Rev. Pharmacol. Toxicol. 36: 83-106
30. Singleton, V. L., Orthofer, R., Lamuela-Raventos, R. M. (1999) Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol. 299: 152-178
31. Trevisi, L., Pighin, I., Bazzan, S., Luciani, S. (2006) Inhibition of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) endocytosis by ouabain in human endothelial cells. FEBS Lett. 580: 2769-2773
32. Whittemore, E. R., Loo, D. T., Cotman, C. W. (1994) Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons. Neuroreport 5: 1485-1488
33. Wu, M. D., Huang, R. L., Kuo, L. M. Y., Hung, C. C., Ong, C. W., Kuo, Y. H. (2003) The anti-HBsAg (human type B hepatitis, surface antigen) and anti-HBeAg (human type B hepatitis, e antigen) C18 dibenzocyclooctadiene lignans from Kadsura matsudai and Schizandra arisanensis. Chem. Pharm. Bull. 51: 1233-1236
34. Yasukawa, K., Ikeya, Y., Mitsuhashi, H., Iwasaki, M., Aburada, M., Nakagawa, S., Takeuchi, M., Takido, M. (1992) Gomisin A inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Oncology 49: 68-71
35. 12 cells against damage from oxidative stress. Biochem. Biophys. Res. Commun. 344: 394-399