Polypharmacy in elderly patients at discharge from the acute care hospital

Therapeutics and Clinical Risk Management

Volumn 3, Issue 1, 2007, Pages 197-203

  Corsonello, Andrea ^a   Pedone, Claudio ^b   Corica, Francesco ^c   Incalzi, Raffaele Antonelli ^b  

^a INRCA   (Italy)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

Comorbidity; Elderly; Epidemiology; Polypharmacy

Indexed keywords

ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTIDEPRESSANT AGENT; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANXIOLYTIC AGENT; BRONCHODILATING AGENT; DIGITALIS; DIGOXIN; DIURETIC AGENT; STEROID;

ADULT; AGED; ARTICLE; ASTHMA; CEREBROVASCULAR DISEASE; CHRONIC DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL PRACTICE; COMORBIDITY; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; DEPRESSION; DIABETES MELLITUS; ELDERLY CARE; EMERGENCY CARE; FEMALE; HEART ATRIUM FIBRILLATION; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; HYPERTENSION; KIDNEY FAILURE; LENGTH OF STAY; LIVER FAILURE; LOGISTIC REGRESSION ANALYSIS; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; PERIPHERAL VASCULAR DISEASE; POLYPHARMACY; PRACTICE GUIDELINE; PRESCRIPTION; RHINITIS; THROMBOPHLEBITIS;

EID: 34247618752     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: 10.2147/tcrm.2007.3.1.197     Document Type: Article

References (37)

1. [ATS] American Thoracic Society. 1995. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 5(Pt 2):S77-S121.
2. Antonelli Incalzi R, Pedone C, Pahor M, et al. 2001. Reasons prompting digitalis therapy in the acute care hospital. J Gerontol A Biol Sci Med Sci, 56:M361-5.
3. Antonelli Incalzi R, Corsonello A, Pedone C, et al. 2005. Depression and drug utilization in an older population. Ther Clin Risk Manag, 1:55-60.
4. Aronow WS. 1996. Prevalence of appropriate and inappropriate indications for use of digoxin in older patients at the time of admission to a nursing home. J Am Geriatr Soc, 44:588-90.
5. Atkin PA, Shenfield GM. 1995. Medication-related adverse reactions and the elderly: aliterature review. Adv Drug React Toxicol Rev, 14:175-91.
6. Boyd CM, Darer J, Boult C, et al. 2005. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA, 294:716-24.
7. Carosella L, Pahor M, Pedone C, et al. 1999. Pharmacosurveillance in hospitalized patients in Italy. Study design of the 'Gruppo Italiano di Farmacovigilanza nell'Anziano'(GIFA). Pharmacol Res, 40:287-95.
8. Chang CM, Liu PY, Yang YH, et al. 2005. Use of the Beers criteria to predict adverse drug reactions among first-visit elderly outpatients. Pharmacotherapy, 25:831-8.
9. Chen YF, Dewey ME, Avery AJ. 2001. Analysis Group of The Medical Research Council Cognitive Function and Ageing (MRCCFA) Study. Self-reported medication use for older people in England and Wales. J Clin Pharm Ther, 26:129-40.
10. Corsonello A, Pedone C, Corica F, et al. 1999. Atitihypertensive drug therapy and hypoglycemia in elderly diabetic patients treated with insulin and/or sulfonylureas. Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA). Eur J Epidemiol, 15:893-901.
11. Corsonello A, Pedone C, Corica F, et at. 2005. Concealed renal insufficiency and adverse drug reactions in elderly hospitalized patients. Arch Intern Med, 165:790-5.
12. Haas GJ, Young JB. 1999. Inappropriate use of digoxin in the elderly: how widespread is the problem and how can it be solved? Drug Saf 20:223-30.
13. Hajjar ER, Hanlon JT, Artz MB, et al. 2003. Adverse drug reaction risk factors in older outpatients. Am J Geriatr Pharmacother 1:82-9.
14. Jitapunkul S, Pillay I, Ebrahim S. 1991. The abbreviated mental test: its use and validity. Age Ageing, 20:332-6.
15. Katz S, Ford AB, Moskowitz RW, et al. 1963. Studies of illness in aged: the index of ADL, a standardized measure of biological and psychosocial function. JAMA, 185:94-106.
16. Kelly J, Chamber J. 2000. Inappropriate use of loop diuretics in elderly patients. Age Ageing, 29:489-93.
17. Kwon OY, Jung DY, Kim Y, et al. 2003. Effects ofankle exercise combined with deep breathing on blood flow velocity in the femoral vein. Aust J Physiother, 49:253-8.
18. Lenze EJ, Mulsant BH, Shear MK, et al. 2001. Comorbidity of depression and anxiety disorders in later life. Depress Anxiety, 14:86-93.
19. Lesher EL, Berryhill JS. 1994. Validation ofthe Geriatric Depression Scale-Short Form among inpatients. J Clin Psychol, 50:256-60.
20. Mannesse CK, Derkx FH, de Ridder MA, et al. 2000. Contribution of adverse drug reactions to hospital admission of older patients. Age Ageing, 29:35-9.
21. Masoudi FA, Baillie CA, Wang Y, et al. 2005. The complexity and cost of drug regimens of older patients hospitalized with heart failure in the United States, 1998-2001. Arch Intern Med, 165:2069-76.
22. McCall WW. 2005. Diagnosis and management ofinsomnia in older people. J Am Geriatr Soc, 53(7 Suppl):S272-7.
23. Naranjo CA, Busto U, Sellers EM, et al. 1981. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther, 30:239-45.
24. Onder G, Pedone C, Landi F, et al. 2002. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc, 50:1962-8.
25. Onder G, Gambassi G, Scales CJ, et al. 2002. Adverse drug reactions and cognitive function among hospitalized older adults. Eur J Clin Pharmacol, 58:371-7.
26. Onder G, Landi F, Cesari M, et al. 2003. Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly. Eur J Clin Pharmacol, 59:157-62.
27. Onder G, Landi F, Liperoti R, et al. 2005. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol, 61:453-9.
28. Pahor M, Chrischilles EA, Guralnik JM, et al. 1994. Drug data coding and analysis in epidemiologic studies. Eur J Epidemiol, 10:405-11.
29. Pirmohamed M, James S, Meakin S, et al. 2004. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. BMJ, 329:15-19.
30. Radecki SE, Kane RL, Solomon DH, ct al. 1988. Do physicians spend less time with older patients? J Am Geriatr Soc, 36:713-18.
31. Rocca WA, Bonaiuto S, Lippi A, et al. 1992. Validation of the Hodkinson Abbreviated Mental Test as a screening instrument for dementia in an Italian population. Neuroepidemiology, 11:288-295.
32. Simons LA, Tett S, Simons J, et al. 1992. Multiple medication use in the elderly. Use ofprescription and non-prescription drugs in an Australian community setting. Med J Aust, 157:242-6.
33. Somers A, Petrovic M, Robays H, et al. 2003. Reporting adverse drug reactions on a geriatric ward: a pilot project. Eur J Clin Pharmacol, 58:707-14.
34. Stek ML, Gussekloo J, Beekman AT, et al. 2004. Prevalence, correlates and recognition of depression in the oldest old: the Leiden 85-plus study. J Affect Disord, 78:193-200.
35. Tinetti ME, Bogardus ST Jr, Agostini YV. 2004. Potential pitfalls of disease-specific guidelines for patients with multiple conditions. N Engl J Med, 351:2870-4.
36. van Kraaij DJ, Jansen RW, Gribnau FW, et al. 1998. Loop diuretics in patients aged 75 years or older: general practitioners' assessment of indications and possibilities for withdrawal. Eur J Clin Pharmacol, 54:323-7.
37. [WHO] World Health Organization. 1980. PHS-HCF. International classification of diseases, 9th revision. Clinical modifications. Public Health Service-Health Care Financing Administration, Washington, D.C.