Clinical sample investigation (CSI) hematology: Pinpointing the precise onset of heparin-induced thrombocytopenia (HIT) [12]

Journal of Thrombosis and Haemostasis

Volumn 5, Issue 3, 2007, Pages 636-637

  Warkentin, Theodore E ^a,b   Sheppard, J I ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b HAMILTON REGIONAL LABORATORY MEDICINE PROGRAM   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CELLULOSE; CITRATE SODIUM; DANAPAROID; EDETIC ACID; FC RECEPTOR; FRESH FROZEN PLASMA; HEPARIN; IMMUNOGLOBULIN G ANTIBODY; LITHIUM; THROMBOCYTE FACTOR 4; ANION EXCHANGE RESIN; ANTIBODY; ANTICOAGULANT AGENT; DRUG DERIVATIVE; EPICHLOROHYDRIN TRIETHANOLAMINE CELLULOSE; UNCLASSIFIED DRUG;

AGED; ANION EXCHANGE; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; CASE REPORT; DISEASE COURSE; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; ECHOGRAPHY; ENZYME IMMUNOASSAY; ERYTHROCYTE; FEMALE; HEART SURGERY; HEPARIN INDUCED THROMBOCYTOPENIA; HUMAN; LETTER; MITRAL VALVE DISEASE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SEROCONVERSION; SEROTONIN RELEASE; THROMBOCYTE COUNT; BLOOD; CHEMICALLY INDUCED DISORDER; HEMATOLOGY; IMMUNOLOGY; ION EXCHANGE; METHODOLOGY; THROMBOCYTOPENIA; TIME;

AGED; ANION EXCHANGE RESINS; ANTIBODIES; ANTICOAGULANTS; CARDIAC SURGICAL PROCEDURES; CELLULOSE; FEMALE; HEMATOLOGY; HEPARIN; HUMANS; IMMUNOENZYME TECHNIQUES; ION EXCHANGE; PLATELET COUNT; PLATELET FACTOR 4; POSTOPERATIVE PERIOD; THROMBOCYTOPENIA; TIME FACTORS;

EID: 34247617785     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2007.02360.x     Document Type: Letter

References (5)

1. Pouplard C, May MA, Regina S, Marchand M, Fusciardi J, Gruel Y. Changes in platelet count after cardiac surgery can effectively predict the development of pathogenic heparin-dependent antibodies. Br J Haematol 2005; 128: 837-41.
2. Warkentin TE, Greinacher A. Heparin-induced thrombocytopenia: recognition, treatment, and prevention. The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004; 126 (3 Suppl.): 311S-37S.
3. Warkentin TE, Sheppard JI. No significant improvement in diagnostic specificity of an anti-PF4/polyanion immunoassay with use of high heparin confirmatory procedure. J Thromb Haemost 2006; 4: 281-2.
4. Visentin GP, Ford SE, Scott PJ, Aster RH. Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J Clin Invest 1994; 93: 81-8.
5. Warkentin TE, Kelton JG. Delayed-onset heparin-induced thrombocytopenia and thrombosis. Ann Intern Med 2001; 135: 502-6.