메뉴 건너뛰기




Volumn 32, Issue 1, 2007, Pages 37-44

Tomopenem. Carbapenem antibiotic

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMPICILLIN; ANTIBIOTIC AGENT; BIAPENEM; CARBAPENEM; CEFTAZIDIME; CEFTRIAXONE; CILASTATIN; CS 023; ERTAPENEM; IMIPENEM; LEVOFLOXACIN; MEROPENEM; PANIPENEM; R 115685; R 1558; RO 4098463; TOMOPENEM; UNCLASSIFIED DRUG; VANCOMYCIN;

EID: 34247596511     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2007.032.01.1070582     Document Type: Article
Times cited : (3)

References (42)
  • 1
    • 0037588773 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of novel parenteral carbapenems, CS-023 (R-115685) and related compounds containing an amidine moiety
    • Kawamoto, I., Shimoji, Y., Kanno, O. et al. Synthesis and structure-activity relationships of novel parenteral carbapenems, CS-023 (R-115685) and related compounds containing an amidine moiety. J Antibiot 2003, 56(6): 565-79.
    • (2003) J Antibiot , vol.56 , Issue.6 , pp. 565-579
    • Kawamoto, I.1    Shimoji, Y.2    Kanno, O.3
  • 2
    • 34247596295 scopus 로고    scopus 로고
    • R-115685, a novel parenteral carbapenem: Synthesis and structure-activity relationships
    • Sept 17-20, Toronto, Abst F-1229
    • Kawamoto, I., Shimoji, Y., Kanno, O. et al. R-115685, a novel parenteral carbapenem: Synthesis and structure-activity relationships. 40th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Toronto) 2000, Abst F-1229.
    • (2000) 40th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Kawamoto, I.1    Shimoji, Y.2    Kanno, O.3
  • 3
    • 34247560575 scopus 로고    scopus 로고
    • Kasai, T, Fujimoto, K, Sankyo Co, Ltd, Process for producing carbapenem-type antibacterial. EP 1338596, JP 2002212183, US 2003225055, US 2006009508, US 7091363, WO 0240482
    • Kasai, T., Fujimoto, K. (Sankyo Co., Ltd.). Process for producing carbapenem-type antibacterial. EP 1338596, JP 2002212183, US 2003225055, US 2006009508, US 7091363, WO 0240482.
  • 4
    • 34247622678 scopus 로고    scopus 로고
    • Kawamoto, I, Fukuhara, H, Shimoji, Y, Sankyo Co, Ltd, Crystalline 1-methylcarbapenem derivatives. JP 2001072681, US 2002128254, US 2003158174, US 2003232803, US 6924279, WO 0102401
    • Kawamoto, I., Fukuhara, H., Shimoji, Y. (Sankyo Co., Ltd.). Crystalline 1-methylcarbapenem derivatives. JP 2001072681, US 2002128254, US 2003158174, US 2003232803, US 6924279, WO 0102401.
  • 6
    • 10444287383 scopus 로고    scopus 로고
    • As antibiotic discovery stagnates, a public health crisis brews, July
    • Bad bugs, no drugs. As antibiotic discovery stagnates, a public health crisis brews, July 2004. http://www.idsociety.org.
    • (2004) Bad bugs, no drugs
  • 7
    • 24344466955 scopus 로고    scopus 로고
    • Lactams against methicillin-resistant Staphylococcus aureus
    • Guignard, B., Entenza, J.M., Moreillon, P. β-Lactams against methicillin-resistant Staphylococcus aureus. Curr Opin Pharmacol 2005, 5(5): 479-89.
    • (2005) Curr Opin Pharmacol , vol.5 , Issue.5 , pp. 479-489
    • Guignard, B.1    Entenza, J.M.2    Moreillon3    β-, P.4
  • 9
    • 0035206589 scopus 로고    scopus 로고
    • Comparative antibacterial activity of carbapenems against P. aeruginosa (1)
    • Hikida, M., Terashima, S., Sato, Y., Okamoto, R., Inoue, M. Comparative antibacterial activity of carbapenems against P. aeruginosa (1). Jpn J Anbitiot 2001, 54: 571-9.
    • (2001) Jpn J Anbitiot , vol.54 , pp. 571-579
    • Hikida, M.1    Terashima, S.2    Sato, Y.3    Okamoto, R.4    Inoue, M.5
  • 10
    • 4444247352 scopus 로고    scopus 로고
    • Evaluation of the cephalosporins, cefepime, cefpirome and ceftazidime, against clinical isolates of imipenem-resistant Pseudomonas aeruginosa
    • Sader, H.S., Cerbara, E.F., Luz, D. et al. Evaluation of the cephalosporins, cefepime, cefpirome and ceftazidime, against clinical isolates of imipenem-resistant Pseudomonas aeruginosa. Braz J Infect Dis 1999, 3: 231-7.
    • (1999) Braz J Infect Dis , vol.3 , pp. 231-237
    • Sader, H.S.1    Cerbara, E.F.2    Luz, D.3
  • 11
    • 0022553016 scopus 로고
    • Emergence of resistance to imipenem during therapy for Pseudomonas aeruginosa infections
    • Quinn, J.P., Dudek, E.J., DiVincenzo, C.A., Lucks, D.A., Lerner, S.A. Emergence of resistance to imipenem during therapy for Pseudomonas aeruginosa infections. J Infect Dis 1986, 154: 289-94.
    • (1986) J Infect Dis , vol.154 , pp. 289-294
    • Quinn, J.P.1    Dudek, E.J.2    DiVincenzo, C.A.3    Lucks, D.A.4    Lerner, S.A.5
  • 12
  • 13
    • 0004565964 scopus 로고    scopus 로고
    • R-115685, a novel parenteral carbapenem: Mode of action and resistance mechanisms
    • Sept 17-20, Toronto, Abst F-1231
    • Masuda, N., Ohya, S., Takenouchi, T. et al. R-115685, a novel parenteral carbapenem: Mode of action and resistance mechanisms. 40th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 17-20, Toronto) 2000, Abst F-1231.
    • (2000) 40th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Masuda, N.1    Ohya, S.2    Takenouchi, T.3
  • 14
    • 4444266407 scopus 로고    scopus 로고
    • CS-023 (R-115685), a novel carbapenem with enhanced in vitro activity against oxacillin-resistant staphylococci and Pseudomonas aeruginosa
    • Thomson, K.S., Moland, E.S. CS-023 (R-115685), a novel carbapenem with enhanced in vitro activity against oxacillin-resistant staphylococci and Pseudomonas aeruginosa. J Antimicrob Chemother 2004, 54(2): 557-62.
    • (2004) J Antimicrob Chemother , vol.54 , Issue.2 , pp. 557-562
    • Thomson, K.S.1    Moland, E.S.2
  • 17
    • 23044456601 scopus 로고    scopus 로고
    • In vitro and in vivo antibacterial activities of CS-023 (RO4908463), a novel parenteral carbapenem
    • Koga, T., Abe, T., Inoue, H. et al. In vitro and in vivo antibacterial activities of CS-023 (RO4908463), a novel parenteral carbapenem. Antimicrob Agents Chemother 2005, 49(8): 3239-50.
    • (2005) Antimicrob Agents Chemother , vol.49 , Issue.8 , pp. 3239-3250
    • Koga, T.1    Abe, T.2    Inoue, H.3
  • 19
    • 34247588011 scopus 로고    scopus 로고
    • Activity of RO4908463 (CS-023), an investigational carbapenem, against select Gram-positive and Gram-negative pathogens
    • ICAAC, Oct 30-Nov 2, Washington, D.C, Abst E-2017
    • Jones, M.E., Draghi, D.C., Thornsberry, C., Flamm, R.K., Karlowsky, J.A., Sahm, D.F. Activity of RO4908463 (CS-023), an investigational carbapenem, against select Gram-positive and Gram-negative pathogens. 44th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Oct 30-Nov 2, Washington, D.C.) 2004, Abst E-2017.
    • (2004) 44th Intersci Conf Antimicrob Agents Chemother
    • Jones, M.E.1    Draghi, D.C.2    Thornsberry, C.3    Flamm, R.K.4    Karlowsky, J.A.5    Sahm, D.F.6
  • 21
    • 34247596807 scopus 로고    scopus 로고
    • Baseline profile of RO4908463 (CS-023) against recent isolates of target Gram-positive pathogens exhibiting key resistance phenotypes
    • ICAAC, Sept 27-30, San Rrancisco, Abst E-228
    • Jones, M.E., Cohen, M.A., Brown, N.P., Dannemann, B., Sahm, D.F. Baseline profile of RO4908463 (CS-023) against recent isolates of target Gram-positive pathogens exhibiting key resistance phenotypes. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Rrancisco) 2006, Abst E-228.
    • (2006) 46th Intersci Conf Antimicrob Agents Chemother
    • Jones, M.E.1    Cohen, M.A.2    Brown, N.P.3    Dannemann, B.4    Sahm, D.F.5
  • 22
    • 34247596807 scopus 로고    scopus 로고
    • Baseline profile of RO4908463 (CS-023) against recent isolates of target Gram-negative pathogens exhibiting beta-lactam resistance phenotypes
    • Sept 27-30, San Francisco, Abst C2-1835
    • Jones, M.E., Cohen, M.A., Brown, N.P., Dannemann, B., Sahm, D.F. Baseline profile of RO4908463 (CS-023) against recent isolates of target Gram-negative pathogens exhibiting beta-lactam resistance phenotypes. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst C2-1835.
    • (2006) 46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Jones, M.E.1    Cohen, M.A.2    Brown, N.P.3    Dannemann, B.4    Sahm, D.F.5
  • 24
    • 34247567738 scopus 로고    scopus 로고
    • Jones, M.E., Cohen, M.A., Brown, N.P., Dannemann, B., Sahm, D.F. RO4908463 (CS-023) demonstrates a low potential for in vitro selection of resistance in S. aureus (SA) E. coli (EC) and P. aeruginosa (PA). 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst C1-35.
    • Jones, M.E., Cohen, M.A., Brown, N.P., Dannemann, B., Sahm, D.F. RO4908463 (CS-023) demonstrates a low potential for in vitro selection of resistance in S. aureus (SA) E. coli (EC) and P. aeruginosa (PA). 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst C1-35.
  • 25
    • 63849147020 scopus 로고    scopus 로고
    • The RO4908463 (CS-023) T>MIC antibacterial effect relationship for MRSA established in an in vitro pharmacokinetic model of infection
    • Sept 27-30, San Francisco, Abst A-638
    • Noel, A.R., Bowker, K.E., MacGowan, A.P. The RO4908463 (CS-023) T>MIC antibacterial effect relationship for MRSA established in an in vitro pharmacokinetic model of infection. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-638.
    • (2006) 46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Noel, A.R.1    Bowker, K.E.2    MacGowan, A.P.3
  • 26
    • 63849147020 scopus 로고    scopus 로고
    • The antibacterial effect of RO4908463 (CS-023) on MRSA studied in an in vitro pharmacokinetic model of infection
    • Sept 27-30, San Francisco, Abst A-637
    • Noel, A.R., Bowker, K.E., MacGowan, A.P. The antibacterial effect of RO4908463 (CS-023) on MRSA studied in an in vitro pharmacokinetic model of infection. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-637.
    • (2006) 46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Noel, A.R.1    Bowker, K.E.2    MacGowan, A.P.3
  • 27
    • 34147177092 scopus 로고    scopus 로고
    • Pharmacodynamics of RO4908463 (CS-023), a novel carbapenem, against Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PSA)
    • ICAAC, Oct 30-Nov 2, Washington, D.C, Abst A-141
    • Kuti, J.L., Nightingale, C., Nicolau, D.P. Pharmacodynamics of RO4908463 (CS-023), a novel carbapenem, against Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PSA). 44th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Oct 30-Nov 2, Washington, D.C.) 2004, Abst A-141.
    • (2004) 44th Intersci Conf Antimicrob Agents Chemother
    • Kuti, J.L.1    Nightingale, C.2    Nicolau, D.P.3
  • 28
    • 34247620136 scopus 로고    scopus 로고
    • Pharmacodynamics of RO4908463 (CS-023) for the empiric treatment of nosocomial pneumonia
    • IDSA, Sept 30-Oct 3, Boston, Abst 320
    • Sun, H.K., Kuti, J.L., Nightingale, C., Nicolau, D.P. Pharmacodynamics of RO4908463 (CS-023) for the empiric treatment of nosocomial pneumonia. 42nd Annu Meet Infect Dis Soc Am (IDSA) (Sept 30-Oct 3, Boston) 2004, Abst 320.
    • (2004) 42nd Annu Meet Infect Dis Soc Am
    • Sun, H.K.1    Kuti, J.L.2    Nightingale, C.3    Nicolau, D.P.4
  • 29
    • 34247648511 scopus 로고    scopus 로고
    • CS-023 (R-115685), a novel parenteral carbapenem: I. In vitro and in vivo pharmacodynamic (PD) evaluations against Pseudomonas aeruginosa
    • ICAAC, Sept 22-25, Chicago, Abst F-365
    • Koga, T., Fukuoka, T., Ishii, C. et al. CS-023 (R-115685), a novel parenteral carbapenem: I. In vitro and in vivo pharmacodynamic (PD) evaluations against Pseudomonas aeruginosa. 41st Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 22-25, Chicago) 2001, Abst F-365.
    • (2001) 41st Intersci Conf Antimicrob Agents Chemother
    • Koga, T.1    Fukuoka, T.2    Ishii, C.3
  • 30
    • 34247627250 scopus 로고    scopus 로고
    • CS-023 (R-115685), a novel parenteral carbapenem: II. In vitro and in vivo activities against methicillin-resistant Staphylococcus aureus
    • ICAAC, Sept 22-25, Chicago, Abst F-366
    • Fukuoka, T., Koga, T., Ishii, C. et al. CS-023 (R-115685), a novel parenteral carbapenem: II. In vitro and in vivo activities against methicillin-resistant Staphylococcus aureus. 41st Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 22-25, Chicago) 2001, Abst F-366.
    • (2001) 41st Intersci Conf Antimicrob Agents Chemother
    • Fukuoka, T.1    Koga, T.2    Ishii, C.3
  • 31
    • 33748525334 scopus 로고    scopus 로고
    • High affinity for PBP 2′ enables RO490-8463 (CS-023), a unique guanidine-pyrrolidine carbapenem, to achieve good in vitro activity against MRSA, which is confirmed in murine infection models
    • April 2-5, Copenhagen, Abst P1572
    • Namba, E., Inoue, H., Koga, T., Fukuoka, T., Simpson, I. High affinity for PBP 2′ enables RO490-8463 (CS-023), a unique guanidine-pyrrolidine carbapenem, to achieve good in vitro activity against MRSA, which is confirmed in murine infection models. Clin Microbiol Infect [15th Eur Congr Clin Microbiol Infect Dis (ECCMID) (April 2-5, Copenhagen) 2005] 2005, 11(Suppl. 2): Abst P1572.
    • (2005) Clin Microbiol Infect [15th Eur Congr Clin Microbiol Infect Dis (ECCMID) , vol.11 , Issue.SUPPL. 2
    • Namba, E.1    Inoue, H.2    Koga, T.3    Fukuoka, T.4    Simpson, I.5
  • 33
    • 34247586487 scopus 로고    scopus 로고
    • Antibacterial activity of CS-023 against MRSA and Pseudomonas aeruginosa
    • Sept 27-30, San Diego, Abst F-324
    • Fukuoka, T., Koga, T., Ishii, C. et al. Antibacterial activity of CS-023 against MRSA and Pseudomonas aeruginosa. 42nd Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Diego) 2002, Abst F-324.
    • (2002) 42nd Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Fukuoka, T.1    Koga, T.2    Ishii, C.3
  • 34
    • 33845662120 scopus 로고    scopus 로고
    • Renal handling of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in rabbits in comparison with meropenem
    • Shibayama, T., Yamamura, N., Matsushita, Y., Tokui, T., Hirota, T., Ikeda, T. Renal handling of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in rabbits in comparison with meropenem. Xenobiotica 2006, 36(12): 1273-87.
    • (2006) Xenobiotica , vol.36 , Issue.12 , pp. 1273-1287
    • Shibayama, T.1    Yamamura, N.2    Matsushita, Y.3    Tokui, T.4    Hirota, T.5    Ikeda, T.6
  • 35
    • 34247592783 scopus 로고    scopus 로고
    • CS-023 (RO4908463) and meropenem exhibit different renal excretion behaviour in rabbits
    • Sept 27-30, San Francisco, Abst A-1940
    • Yamamura, N. CS-023 (RO4908463) and meropenem exhibit different renal excretion behaviour in rabbits. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1940.
    • (2006) 46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Yamamura, N.1
  • 36
    • 33845997465 scopus 로고    scopus 로고
    • Pharmacokinetics and disposition of CS-023 (RO4908463), a novel parenteral carbapenem, in animals
    • Shibayama, T., Matsushita, Y., Kawai, K., Hirota, T., lkeda, T., Kuwahara, S. Pharmacokinetics and disposition of CS-023 (RO4908463), a novel parenteral carbapenem, in animals. Antimicrob Agents Chemother 2007, 51(1): 257-63.
    • (2007) Antimicrob Agents Chemother , vol.51 , Issue.1 , pp. 257-263
    • Shibayama, T.1    Matsushita, Y.2    Kawai, K.3    Hirota, T.4    lkeda, T.5    Kuwahara, S.6
  • 38
    • 33845769429 scopus 로고    scopus 로고
    • Prediction of pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in humans using animal data
    • Shibayama, T., Matsushita, Y., Kurihara, A., Hirota, T., Ikeda, T. Prediction of pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem antibiotic, in humans using animal data. Xenobiotica 2007, 37(1): 91-102.
    • (2007) Xenobiotica , vol.37 , Issue.1 , pp. 91-102
    • Shibayama, T.1    Matsushita, Y.2    Kurihara, A.3    Hirota, T.4    Ikeda, T.5
  • 39
    • 34247571777 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics (PK) of CS-023, a new parenteral carbapenem, in healthy male volunteers
    • Sept 27-30, San Diego, Abst F-327
    • Rennecke, J., Hirota, T., Shibayama, T. et al. Safety, tolerability, and pharmacokinetics (PK) of CS-023, a new parenteral carbapenem, in healthy male volunteers. 42nd Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Diego) 2002, Abst F-327.
    • (2002) 42nd Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Rennecke, J.1    Hirota, T.2    Shibayama, T.3
  • 40
    • 33845246106 scopus 로고    scopus 로고
    • Pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem, in healthy male Caucasian volunteers
    • Shibayama, T., Matsushita, Y., Hirota, T., Ikeda, T., Kuwahara, S. Pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem, in healthy male Caucasian volunteers. Antimicrob Agents Chemother 2006, 50(12): 4186-8.
    • (2006) Antimicrob Agents Chemother , vol.50 , Issue.12 , pp. 4186-4188
    • Shibayama, T.1    Matsushita, Y.2    Hirota, T.3    Ikeda, T.4    Kuwahara, S.5
  • 41
    • 34247577092 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of CS-023 (RO4908463), a new parenteral carbapenem in healthy Japanese male volunteers
    • Sept 27-30, San Francisco, Abst A-1941
    • Sesoko, S., Morita, K., Tajima, N., Nakashima, M. Safety, tolerability, and pharmacokinetics of CS-023 (RO4908463), a new parenteral carbapenem in healthy Japanese male volunteers. 46th Intersci Conf Antimicrob Agents Chemother (ICAAC) (Sept 27-30, San Francisco) 2006, Abst A-1941.
    • (2006) 46th Intersci Conf Antimicrob Agents Chemother (ICAAC)
    • Sesoko, S.1    Morita, K.2    Tajima, N.3    Nakashima, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.