Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors

Journal of Medicinal Chemistry

Volumn 50, Issue 9, 2007, Pages 2137-2143

  Vazquez, Jesus ^a   Tautz, Lutz ^a   Ryan, Jennifer J ^a   Vuori, Kristiina ^a   Mustelin, Tomas ^a   Pellecchia, Maurizio ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; FURAN DERIVATIVE; NITROXIDE DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; PROTEIN YOPH; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; IC 50; MOLECULAR PROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SPIN LABELING; YERSINIA PESTIS;

BACTERIAL OUTER MEMBRANE PROTEINS; CATALYTIC DOMAIN; CYCLIC N-OXIDES; FURANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN-TYROSINE-PHOSPHATASE; SALICYLATES; SPIN LABELS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34247592309     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm061481l     Document Type: Article

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