Early and late arrhythmogenic effects of doxorubicin

Southern Medical Journal

Volumn 100, Issue 3, 2007, Pages 262-265

  Kilickap, Saadettin ^a   Barista, Ibrahim ^a   Akgul, Ebru ^a   Aytemir, Kudret ^a   Aksoy, Sercan ^a   Tekuzman, Gulten ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Arrhythmia; Cardiotoxicity; Doxorubicin

Indexed keywords

CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; FLUOROURACIL; PREDNISONE; VINCRISTINE; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC;

ADULT; AGED; ARRHYTHMOGENESIS; ARTICLE; ARTIFICIAL HEART PACEMAKER; ATRIOVENTRICULAR BLOCK; CANCER CHEMOTHERAPY; CANCER PATIENT; CLINICAL ARTICLE; COMPLETE HEART BLOCK; CONTROLLED STUDY; FEMALE; HOLTER MONITORING; HUMAN; MALE; MULTIPLE CYCLE TREATMENT; PROSPECTIVE STUDY; SYNCOPE; TREATMENT OUTCOME; ADOLESCENT; BREAST TUMOR; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ELECTROCARDIOGRAPHY; EXTRASYSTOLE; FOLLOW UP; HEART; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART BLOCK; LYMPHOMA; MIDDLE AGED; NASOPHARYNX TUMOR; SINUS ARRHYTHMIA; TACHYCARDIA;

ADOLESCENT; ADULT; AGED; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ARRHYTHMIA; ARRHYTHMIA, SINUS; ATRIAL FIBRILLATION; BREAST NEOPLASMS; CARDIAC COMPLEXES, PREMATURE; DOXORUBICIN; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; FOLLOW-UP STUDIES; HEART; HEART BLOCK; HUMANS; LYMPHOMA; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; PROSPECTIVE STUDIES; SYNCOPE; TACHYCARDIA;

EID: 34247581388     PISSN: 00384348     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.smj.0000257382.89910.fe     Document Type: Article

References (20)

1. Keefe DL. Anthracycline-induced cardiomyopathy. Semin Oncol 2001;28(Suppl 12):2-7.
2. Kilickap S, Barista I, Akgul E, et al. cTnT can be a useful marker for early detection of anthracycline cardiotoxicity. Ann Oncol 2005;16:798-804.
3. Meinardi MT, van der Graff WTA, van Veldhuisen DJ, et al. Detection of anthracycline-induced cardiotoxicity. Cancer Treat Rev 1999;25:237-247.
4. Steinberg JS, Cohen AJ, Wasserman AG, et al. Acute arrhythmogenicity of doxorubicin administration. Cancer 1987;60:1213-1218.
5. Friess GG, Boyd JF, Geer MR, et al. Effects of first-dose doxorubicin on cardiac rhythm as evaluated by continuous 24-hour monitoring. Cancer 1985;56:2762-2764.
6. Kilickap S, Akgul E, Aksoy S, et al. Doxorubicin-induced second degree and complete atrioventricular block. Europace 2005;7:227-230.
7. Shan K, Lincoff AM, Young JB. Anthracycline-induced cardiotoxicity. Ann Intern Med 1996;125:47-58.
8. Bristow MR, Kantrowitz NE, Harrison WD, et al. Mediation of subacute anthracycline cardiotoxicity in rabbits by cardiac histamine release. J Cardiovasc Pharmacol 1983;5:913-919.
9. Bristow M, Thompson P, Martin R, et al. Early anthracycline cardiotoxicity. Am J Med 1978;65:823-832.
10. Speyer JL, Ewer MS, Freedberg RS. Cardiac effects of cancer therapy. In: Abeloff MD, Armitage JO, Niederhuber JE, et al, eds. Clinical Oncology. Philadelphia, Churchill Livingstone, 2004, pp. 1251-1268.
11. Robison TW, Giri SN. Effects of chronic administration of doxorubicin on myocardial beta-adrenergic receptors. Life Sci 1986;39:731-6.
12. Benedict CR, Weiner DH, Johnstone DE, et al. Comparative neurohormonal responses in patients with preserved and impaired left ventricular ejection fraction: results of the Studies of Left Ventricular Dysfunction (SOLVD) Registry. J Am Coll Cardiol 1993;22(4 Suppl A):146A-153A.
13. Ali MK, Soto A, Maroongroge D, et al. Electrocardiographic changes after adriamycin chemotherapy. Cancer 1979;43:465-471.
14. Lenaz L, Page JA. Cardiotoxicity of adriamycin and related anthracyclines. Cancer Treat Rep 1976;3:111-120.
15. Wortman JE, Lucas VS, Schuster E, et al. Sudden death during doxorubicin administration. Cancer 1979;44:1588-1591.
16. O'Bryan RM, Luce JK, Talley RW, et al. Phase II evaluation of adriamycin in human neoplasia. Cancer 1973;32:1-8.
17. Lefrak EA, Pitha J, Rosenheim S, et al. A clinicopathologic analysis of adriamycin cardiotoxicity. Cancer 1973;32:302-314.
18. Larsen RL, Jakacki RI, Vetter VL, et al. Electrocardiographic changes and arrhythmias after cancer therapy in children and young adults. Am J Cardiol 1992;70:73-77.
19. Keefe DL. Cardiovascular emergencies in the cancer patient. Semin Oncol 2000;27:244-255.
20. Kasinath NS, Malak O, Tetzlaff J. Atrial fibrillation after ondansetron for the prevention and treatment of postoperative nausea and vomiting: a case report. Can J Anaesth 2003;50:229-231.