Age-related changes in neuronal susceptibility to damage: Comparison of the retinal ganglion cells of young and old mice before and after optic nerve crush

Annals of the New York Academy of Sciences

Volumn 1097, Issue , 2007, Pages 64-66

  Ai, Ling Wang ^a   Yuan, Ming ^a   Neufeld, Arthur H ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Age; Fluoro gold; Optic nerve crush; Retinal ganglion cell

Indexed keywords

AGE DISTRIBUTION; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CELL LOSS; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE PREDISPOSITION; IN VIVO STUDY; MOUSE; NERVE CELL LESION; NERVE CRUSH; NONHUMAN; OPTIC NERVE INJURY; PHENOTYPE; RETINA GANGLION CELL; ANIMAL; ARTICLE; CYTOCHEMISTRY; NERVE CELL; OPTIC NERVE; PHYSIOLOGY;

ANIMALIA; MUS;

2 HYDROXY 4,4' DIAMIDINOSTILBENE, METHANESULFONATE SALT; 2-HYDROXY-4,4'-DIAMIDINOSTILBENE, METHANESULFONATE SALT; FLUORESCENT DYE; STILBAMIDINE; UNCLASSIFIED DRUG;

AGING; ANIMALS; FLUORESCENT DYES; HISTOCYTOCHEMISTRY; MICE; NERVE CRUSH; NEURONS; OPTIC NERVE; RETINAL GANGLION CELLS; STILBAMIDINES;

EID: 34247578812     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1379.027     Document Type: Conference Paper

References (4)

1. KAWAI, S.I., S. VORA, S. DAS, et al. 2001. Modeling of risk factors for the degeneration of retinal ganglion cells after ischemia/reperfusion in rats: effects of age, caloric restriction, diabetes, pigmentation, and glaucoma. FASEB J. 15: 1285-1287.
2. MATTSON, P.M & T. MAGNUS. 2006. Ageing and neuronal vulnerability. Nat. Rev. Neurosci. 7: 278-294.
3. SIERADZAN, K.A. & D.M. MANN. 2001. The selective vulnerability of nerve cells in Huntington's disease. Neuropathol. Appl. Neurobiol. 27: 1-21.
4. NEUFELD, A.H. & E.N. GACHIE. 2003. The inherent, age-dependent loss of retinal ganglion cells is related to the lifespan of the species. Neurobiol. Aging 24: 167-172.