Diffusion model for iontophoresis measured by laser-Doppler perfusion flowmetry, applied to normal and preeclamptic pregnancies

Journal of Biomedical Optics

Volumn 12, Issue 1, 2007, Pages

  De Mul, Frits F M ^a   Blaauw, Judith ^a   Aarnoudse, Jan G ^a   Smit, Andries J ^a   Rakhorst, Gerhard ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Flowmetry; Iontophoresis; Laser Doppler; Preeclampsia; Pregnancy; Tissue perfusion

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ARTICLE; BIOLOGICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; DIFFUSION; FEMALE; HUMAN; IONTOPHORESIS; LASER DOPPLER FLOWMETRY; METHODOLOGY; PATHOPHYSIOLOGY; PREECLAMPSIA; PREGNANCY; REFERENCE VALUE; SKIN; SKIN ABSORPTION;

ANTIHYPERTENSIVE AGENTS; COMPUTER SIMULATION; DIFFUSION; FEMALE; HUMANS; IONTOPHORESIS; LASER-DOPPLER FLOWMETRY; MODELS, BIOLOGICAL; PRE-ECLAMPSIA; PREGNANCY; REFERENCE VALUES; SKIN; SKIN ABSORPTION;

BLOOD; CAPILLARY FLOW; DIFFUSION; FLOWMETERS; TISSUE;

BLOOD PERFUSION; IONTOPHORESIS; PREECLAMPTIC PREGNANCIES; SHOT SATURATION CONSTANT;

LASER DOPPLER VELOCIMETERS;

EID: 34247564629     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2671053     Document Type: Article

References (10)

1. A. K. Banga, Electrically Assisted Transdermal and Topical Drug Delivery, Taylor and Francis, London (1998).
2. S. J. Morris, A. C. Shore, and J. E. Tooke, "Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM," Diabetologia 38, 1337-1344 (1995).
3. E. H. Serne, C. D. Stehouwer, J. C. ter Maaten, P. M. ter Wee, J. A. Rauwerda, and A. J. Donker, "Microvascular function relates to insulin sensitivity and blood pressure in normal subjects," Circulation 99, 896-902 (1999). (Pubitemid 29094303)
4. K. R. Davis, J. Ponnampalam, R. Hayman, P. N. Baker, S. Arulkumaran, and R. Donnelly, "Microvascular vasodilator response to acetylcholine is increased in women with preeclampsia," Br. J. Obstet. Gynaecol. 108, 610-614 (2001). (Pubitemid 33646502)
5. J. Blaauw, R. Graaff, M. G. van Pampus, J. J. van Doormaal, A. J. Smit, G. Rakhorst, and J. A. Aarnoudse, "Abnormal endotheliumdependent microvascular reactivity in recently preeclamptic women," Obstet. Gynecol. (N.Y., NY, U. S.) 105(3), 626-632 (2005). (Pubitemid 40271233)
6. A. Fick, "Über Diffusion," Ann. Phys. Chem. 94, 59 (1855).
7. G. L. Flynn, "Physicochemical determination of skin absorption," in Principles of Route-to-Route Extrapolation for Risk Assessment, T. R. Gerrity and C. J. Henry, Eds., pp. 93-127, Elsevier, New York (1990).
8. R. O. Potts and R. H. Guy, "Predicting skin permeability," Pharm. Res. 9, 663-669 (1992).
9. F. Y. Özbebit, F. Esen, S. Gülec, and H. Esen, "Evaluation of forearm microvascular blood flow regulation by laser Doppler flowmetry, iontophoresis and curve analysis, contribution of axon reflex," Microvasc. Res. 67, 207-214 (2004). (Pubitemid 38581873)
10. R. T. de Jongh, E. H. Serne, R. G. IJzerman, G. de Vries, and C. D. Steehouwer, "Impaired microvascular function in obesity, implications for obesity-associated microangiopathy, hypertension and insulin resistance," Circulation 109, 2529-2535 (2004). (Pubitemid 38720552)