Effects of Persea americana leaf extracts on body weight and liver lipids in rats fed hyperlipidaemic diet

African Journal of Biotechnology

Volumn 6, Issue 8, 2007, Pages 1007-1011

  Brai, B I C ^a,b   Odetola, A A ^b   Agomo, P U ^a  

^a NIGERIAN INSTITUTE OF MEDICAL RESEARCH   (Nigeria)

^b UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Albino rats; Body weight gain; Hyperlipidaemia; Leaf extracts; Persea americana

Indexed keywords

PERSEA AMERICANA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; HYPERLIPIDEMIA; LIPID DIET; LIPID LIVER LEVEL; LIPOLYSIS; MALE; NONHUMAN; PLANT LEAF; RAT; WEIGHT GAIN;

PERSEA AMERICANA; RATTUS;

EID: 34247555953     PISSN: None     EISSN: 16845315     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Akah PA, Ekekwe RK (1995). Ethnopharmacology of some Asteraceae family used in Nigerian traditional medicine. Fitoterapia 66:351-356.
2. Antia BS, Okokon JE, Okon PA (2005). Hypoglycemic activity of aqueous leaf extract of Persea americana Mill. Indian J. Pharmacol. 37: 325-326.
3. Burton BT, Foster WR, Hirsch J, Vanltallie TB (1985). Health implications of obesity: NIH consensus development conference. Int. J. Obes. Relat. Metab. Disord. 9: 155-169.
4. Eckel RH, Kahn R, Robertson RM, Rizza RA (2006). Preventing cardiovascular disease and diabetes: A call to action from the American diabetes Association and American Heart Association. Diabetes Care 29: 1697-1699.
5. Eder K (1999). The effect of a combined dietary treatment with cholesterol and cholic acid on the lipid metabolism of geese at low or high choline concentrations. Arch. Tierernahr. 52: 285-297.
6. Ezzati M, Vander Hoorn S, Lawes CMM, Leach R, James WPT, Lopez AD, Rodgers A, Murray CJL (2005). Rethinking the "diseases of affluence" paradigm: Global patterns of nutritional risks in relation to economic development. PLoS Med. e133 doi:10.1371/journal.pmed.0020133.
7. Folch J, Lees M, Sloane-Stanley GH (1957). A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226: 497-590.
8. Johnston TP, Baker JC, Jamal AS, Hall D, Emeson EE, Palmer WK (1999). Potential down regulation of HMG-CoA reductase after prolonged administration of P-407 in C57BL/6 mice. J. Cardiovasc. Pharmacol. 34: 831-842.
9. Lutz M, Cortez J, Vinet R (1994). Dietary fats and cholesterol supplementation effects on aortic and lipid response in rats. J. Nutr. Biochem. 5:446-450.
10. Morton J (1987). Avocado. In: Fruits of warm climates.ed. Julia F. Morton, Miami FL. 91-102.
11. Palmer WK, Emeson EE, Johnston TP (1998). Poloxamer 407-induced atherogenesis in the C57BL/6 mouse. Atherosclerosis 136:115-123.
12. Popkin BM (2002). An overview on the nutrition transition and its health implications: The Bellagio Meeting. Public Health Nutr. 5:93-103.
13. Reddy KS, Yusuf S (1998). Emerging epidemic of cardiovascular disease in developing countries. Circulation 97:596-601.
14. Sharadi Y Eldad A (2000). Non-alcoholic fatty liver disease is associated with hyperlipidaemia and obesity. Am. J. Med. 109: 171
15. Shefer S, Nguyen LB, Salen G, Ness GC, Chowdhary IR, Lerners S, Batta AK, Tint GS (1992). Differing effects of cholesterol and taurocholate on steady state HMG-CoA reductase and cholesterol 7α-hydroxylase activities and mRNA levels in the rat. J. Lipid Res. 33:1193-1200.
16. Zulet MA, Barber A, Garcin H, Higueret P, Martinez JA (1999). Alteration in carbohydrate and lipid metabolism induced by a diet rich in coconut oil and cholesterol in a rat model. J. Am. Coll. Nutr. 18:36-42.