The inside pH determines rates of electron and proton transfer in vesicle-reconstituted cytochrome c oxidase

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1767, Issue 5, 2007, Pages 381-386

  Faxén, Kristina ^a   Brzezinski, Peter ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Cytochrome aa3; Kinetics; Proton pumping; Respiration; Rhodobacter sphaeroides

Indexed keywords

CYTOCHROME C OXIDASE; PROTON PUMP;

ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PURIFICATION; MEMBRANE; MITOCHONDRION; NONHUMAN; PH; PRIORITY JOURNAL; PROTON TRANSPORT; RHODOBACTER SPHAEROIDES;

BACTERIAL PROTEINS; ELECTRON TRANSPORT COMPLEX IV; ELECTRONS; HYDROGEN-ION CONCENTRATION; KINETICS; PROTEIN CONFORMATION; PROTONS; RHODOBACTER SPHAEROIDES;

RHODOBACTER SPHAEROIDES;

EID: 34247542578     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2007.02.023     Document Type: Article

References (31)

1. Brändén G., Gennis R.B., and Brzezinski P. Transmembrane proton translocation by cytochrome c oxidase. Biochim. Biophys. Acta 1757 (2006) 1052-1063
2. Brzezinski P., and Ädelroth P. Design principles of proton-pumping haem-copper oxidases. Curr. Opin. Struct. Biol. 16 (2006) 465-472
3. Wikström M., and Verkhovsky M.I. Towards the mechanism of proton pumping by the haem-copper oxidases. Biochim. Biophys. Acta, Bioenerg. 1757 (2006) 1047-1051
4. Hosler J.P., Ferguson-Miller S., and Mills D.A. Energy transduction: proton transfer through the respiratory complexes. Ann. Rev. Biochem. 75 (2006) 165-187
5. Svensson-Ek M., Abramson J., Larsson G., Törnroth S., Brzezinski P., and Iwata S. The X-ray crystal structures of wild-type and EQ(I-286) mutant cytochrome c oxidases from Rhodobacter sphaeroides. J. Mol. Biol. 321 (2002) 329-339
6. Qin L., Hiser C., Mulichak A., Garavito R.M., and Ferguson-Miller S. Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 16117-16122
7. Ädelroth P., Ek M., and Brzezinski P. Factors determining electron-transfer rates in cytochrome c oxidase: investigation of the oxygen reaction in the R. sphaeroides and bovine enzymes. Biochim. Biophys. Acta 1367 (1998) 107-117
8. Verkhovsky M.I., Morgan J.E., Verkhovskaya M.L., and Wikström M. Translocation of electrical charge during a single turnover of cytochrome-c oxidase. Biochim. Biophys. Acta 1318 (1997) 6-10
9. Faxén K., Gilderson G., Ädelroth P., and Brzezinski P. A mechanistic principle for proton pumping by cytochrome c oxidase. Nature 437 (2005) 286-289
10. Thörnström P.E., Brzezinski P., Fredriksson P.O., and Malmström B.G. Cytochrome c oxidase as an electron-transport-driven proton pump: pH dependence of the reduction levels of the redox centers during turnover. Biochemistry 27 (1988) 5441-5447
11. Zaslavsky D., Sadoski R.C., Wang K., Durham B., Gennis R.B., and Millett F. Single electron reduction of cytochrome c oxidase compound F: resolution of partial steps by transient spectroscopy. Biochemistry 37 (1998) 14910-14916
12. Oliveberg M., Brzezinski P., and Malmström B.G. The effect of pH and temperature on the reaction of fully reduced and mixed-valence cytochrome c oxidase with dioxygen. Biochim. Biophys. Acta 977 (1989) 322-328
13. Szundi I., Van Eps N., and Einarsdóttir O. pH dependence of the reduction of dioxygen to water by cytochrome c oxidase. 2. Branched electron transfer pathways linked by proton transfer. Biochemistry 42 (2003) 5074-5090
14. Namslauer A., and Brzezinski P. Structural elements involved in electron-coupled proton transfer in cytochrome c oxidase. FEBS Lett. 567 (2004) 103-110
15. Namslauer A., Aagaard A., Katsonouri A., and Brzezinski P. Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase. Biochemsitry 42 (2003) 1488-1498
16. Brändén G., Brändén M., Schmidt B., Mills D.A., Ferguson-Miller S., and Brzezinski P. The protonation state of a heme propionate controls electron transfer in cytochrome c oxidase. Biochemistry 44 (2005) 10466-10474
17. Sharpe M.A., Wrigglesworth J.M., Loewen J., and Nicholls P. Small pH gradients inhibit cytochrome c oxidase: implications for H+ entry to the binuclear center. Biochem. Biophys. Res. Commun. 216 (1995) 931-938
18. Mitchell D.M., and Gennis R.B. Rapid purification of wildtype and mutant cytochrome c oxidase from Rhodobacter sphaeroides by Ni(2+)-NTA affinity chromatography. FEBS Lett. 368 (1995) 148-150
19. Jasaitis A., Verkhovsky M.I., Morgan J.E., Verkhovskaya M.L., and Wikström M. Assignment and charge translocation stoichiometries of the major electrogenic phases in the reaction of cytochrome c oxidase with dioxygen. Biochemistry 38 (1999) 2697-2706
20. Qian J., Shi W., Pressler M., Hoganson C., Mills D., Babcock G.T., and Ferguson-Miller S. Aspartate-407 in Rhodobacter sphaeroides cytochrome c oxidase is not required for proton pumping or manganese binding. Biochemistry 36 (1997) 2539-2543
21. Brändén M., Sigurdson H., Namslauer A., Gennis R.B., Ädelroth P., and Brzezinski P. On the role of the K-proton transfer pathway in cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 5013-5018
22. Brzezinski P., and Malmström B.G. The reduction of cytochrome c oxidase by carbon monoxide. FEBS Lett. 187 (1985) 111-114
23. Siletsky S.A., Pawate A.S., Weiss K., Gennis R.B., and Konstantinov A.A. Transmembrane charge separation during the ferryl-oxo→oxidized transition in a nonpumping mutant of cytochrome c oxidase. J. Biol. Chem. 279 (2004) 52558-52565
24. Verkhovskaya M., Verkhovsky M., and Wikström M. pH dependence of proton translocation by Escherichia coli. J. Biol. Chem. 267 (1992) 14559-14562
25. Capitanio G., Martino P.L., Capitanio N., De Nitto E., and Papa S. pH dependence of proton translocation in the oxidative and reductive phases of the catalytic cycle of cytochrome c oxidase. The role of H2O produced at the oxygen-reduction site. Biochemistry 45 (2006) 1930-1937
26. Zimanyi L., Varo G., Chang M., Ni B., Needleman R., and Lanyi J.K. Pathways of proton release in the bacteriorhodopsin photocycle. Biochemistry 31 (1992) 8535-8543
27. Balashov S.P. Protonation reactions and their coupling in bacteriorhodopsin. Biochim. Biophys. Acta 1460 (2000) 75-94
28. Mills D.A., and Ferguson-Miller S. Influence of structure, pH and membrane potential on proton movement in cytochrome oxidase. Biochim. Biophys. Acta 1555 (2002) 96-100
29. Busenlehner L.S., Salomonsson L., Brzezinski P., and Armstrong R.N. Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 15398-15403
30. Salomonsson L., Faxén K., Ädelroth P., and Brzezinski P. The timing of proton migration in membrane-reconstituted cytochrome c oxidase. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 17624-17629
31. Humphrey W., Dalke A., and Schulten K. VMD: visual molecular dynamics. J. Mol. Graph. 14 (1996) 33