ACE activity during the hypotension produced by standardized aqueous extract of Cecropia glaziovii Sneth: A comparative study to captopril effects in rats

Phytomedicine

Volumn 14, Issue 5, 2007, Pages 321-327

  Ninahuaman, M F M L ^a   Souccar, C ^a   Lapa, A J ^a   Lima Landman, M T R ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Angiotensin converting enzyme; Antihypertensive; Cecropia glaziovii; Hypotension; Phytomedicine

Indexed keywords

CAPTOPRIL; CECROPIA GLAZIOVII EXTRACT; DIPEPTIDYL CARBOXYPEPTIDASE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; FEMORAL ARTERY; HEART RATE; HYPOTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROFLUOROMETRY; UPREGULATION;

ADMINISTRATION, ORAL; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CAPTOPRIL; FEMALE; HEART RATE; HYPERTENSION; PEPTIDYL-DIPEPTIDASE A; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; URTICACEAE;

ANIMALIA; CECROPIA; RATTUS;

EID: 34247521840     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2006.12.010     Document Type: Article

References (38)

1. Adsersen A., and Adsersen H. Plants from Réunion Island with alleged antihypertensive and diuretic effects - an experimental and ethnobotanical evaluation. J. Ethnopharmacol. 58 (1997) 189-206
2. Bormann H., and Melzig M.F. Inhibition of metallopeptidases by flavonoids and related compounds. Pharmazie 55 (2000) 129-132
3. Castro Braga F., Wagner H., Lombardi J.A., and Oliveira A.B. Screening the Brazilian flora for antihypertensive plant species for in vitro angiotensin-I-converting enzyme inhibiting activity. Phytomedicine 7 (2000) 245-250
4. Chen C.H., and Lin J.Y. Inhibition of angiotensin I-converting enzyme by tetrahydroxixanthones isolated from Tripterospermum lanceolatum. J. Nat. Prod. 55 (1992) 691-695
5. Choo H.Y.P., Peak K.H., Park J., Kim D.H., and Chung H.S. Design and synthesis of α, β-unsaturated carbonyl compounds as potential ACE inhibitiors. Eur. J. Med. Chem. 35 (2000) 643-648
6. Della Monache, F., Giacomozzi, C.A., Calixto, J.B., Yunes, R.A., 1988. Isolamento e identificação da isovitexina obtida de frações farmacologicamente ativas da Cecropia glaziovii. X Simpósio de Plantas Medicinais do Brasil, São Paulo, Painel 5/9.
7. Duncan A.C., Jäger A.K., and Staden J. Screening of Zulu medicinal plants for angiotensin converting enzyme (ACE) inhibitors. J. Ethnopharmacol. 68 (1999) 63-70
8. Forslund T., Tikkanen I., Grönhagen-Riska C., and Fyhrquist F. Dissociation of the effect of Captopril on blood pressure and angiotensin converting enzyme in serum and lungs of spontaneously hypertensive rats. Acta Pharmacol. Toxicol. 49 (1981) 416-421
9. Hackl L.P., Cuttle G., Dovichi S.S., Lima-Landman M.T., and Nicolau M. Inhibition of angiotensin-converting enzyme by quercetin alters the vascular response to bradykinin and angiotensin I. Pharmacol 65 (2002) 182-186
10. Hansen K., Adsersen A., Smitt U.W., Nyman U., Christensen S.B., et al. Angiotensin converting enzyme (ACE) inhibitory flavonoids from Erythroxylum laurifolium. Phytomedicine 2 (1996) 313-317
11. Inokuchi J.I., Okabe H., Yamauchi T., Nagamatsu A., Nonaka G., et al. Antihypertensive substance in seeds of Areca catechu L. Life Sci. 38 (1986) 1375-1382
12. Kinoshita E., Yamakoshi J., and Kikuchi M. Purification and identification of an angiotensin I-converting I enzyme inhibitor from soy sauce. Biosci. Biotech. Biochem. 57 (1993) 1107-1110
13. Kokubu T., Ueda E., Ono M., Kawabe T., Hayashi Y., and Kan T. Effects of captopril (SQ 14, 225) on the rennin-angiotensin-aldosterone system in normal rats. Eur. J. Pharmacol. 62 (1980) 269-275
14. Lacaille-Dubois M.A., Franck U., and Wagner H. Search for potencial angiotensin converting enzyme (ACE)-inhibitors from plants. Phytomedicine 8 (2001) 47-52
15. Lapa A.J., Lima-Landman M.T.R., Cysneiros R.M., Borges C.R., Souccar C., et al. A topic on new antihypertensive drug research. In: Hostettsmann K., and Gupta M.P. (Eds). Chemistry, Biological and Pharmacological Properties of Medicinal Plants from the Americas (1999), Harwood Academic Pub., Amsterdam 185-196
16. Lechi A., Covi G., Capuzzo M.G., Lechi C., Minuz P., Delva P., and Scuro L.A. A discrepancy between the effects of a single oral dose of captopril on blood pressure, plasma renin activity, and serum angiotensin-converting enzyme levels. Int. J. Clin. Pharmacol. Ther. Toxicol. 21 (1983) 569-574
17. Li C.Q., Li B.G., Qi H.Y., Li Q.L., Wang F.P., and Zhang G.L. Three cyclooctapeptides and one glycoside from Microtoena prainiana. J. Nat. Prod. 6 (2004) 978-982
18. Lima-Landman, M.T.R., Borges, A.C.R., Cysneiros, R.M., Lima, T.M.A., Souccar, C., Lapa, A.J., 2006. Antihypertensive effect of the standardized aqueous extract of Cecropia glaziovii Sneth: mechanism of the induced hypotension and activity of chemical constituents isolated from the plant. Phytomedicine, submitted for publication.
19. Matos F.J. Plantas Medicinais: Guia de Seleção e Emprego de Plantas Usadas em Fitoterapia no Nordeste do Brasil (1989), IOCE, Fortaleza
20. Michaud A., Williams T.A., Chauvet M.T., and Corvol P. Substrate dependence of Angiotensin I-converting enzyme inhibition: captopril displays a partial selectivity for inhibition of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline hydrolysis compared with that of Angiotensin I. Mol. Pharmacol. 51 (1997) 1070-1076
21. Morigiwa A., Kitabatake K., Fujimoto Y., and Ikekawa N. Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidum. Chem. Pharm. Bull. 34 (1986) 3025-3028
22. Morota T., Saki H., Chin M., Sato T., Katayama N., Fukuyama K., and Mitsuhashi H. Studies on the crude drug containing the angiotensina I converting enzyme inhibitors. I. On the active principles of Lycium chinense Muller. Shoyakugaku Zashi 41 (1987) 169-173
23. Nyman U., Joshi P., Madsen L.B., Pedersen T.B., Pinstrup M., et al. Ethnomedical information and in vitro screening for angiotensin-converting enzyme inhibition of plants utilized as traditional medicines in Gujarat, Rajasthan and Kerala (India). J. Ethnopharmacol. 60 (1998) 247-263
24. Ogino, T., Sato, S., Sasaki, H., Chin M., 1988. Angiotensin I converting enzyme inhibiting activity of tetrandrine, fangchinoline and derivatives there of and pharmaceutical compositions containning them. Patent-Jpn-Kokai Tokkyo Koho JP 62207216 (87207216), Chemical Abstract 109 (11713e) 334.
25. Oparil S., Silfani T.N., and Walter J.F. Role of angiotensin receptor blockers as monotherapy in reaching blood pressure goals. AJH 18 (2005) 187-294
26. Regitz-Zagrosek V., Friedel N., Heymann A., Bauer P., Neuss M., et al. Regulation, chamber localization, and subtype distribution of angiotensin II receptors in human hearts. Circulation 91 (1995) 1461-1471
27. Rocha F.F., Lapa A.J., and De Lima T.C.M. Evaluation of the anxiolytic effects of Cecropia glaziovii Sneth in mice. Pharmacol. Biochem. Behav. 71 (2002) 183-190
28. Rosenthal T., Holtzman E., and Yaron A. Angiotensin-I converting enzyme activity in the sera of Captopril-treated hypertensive patients. Clin. Exper. Hyper-Theory Practice A 4 3 (1982) 367-377
29. Santos R.A.S., Krieger E.M., and Greene L.J. An improved fluorometric assay of rat serum and plasma converting enzyme. Hypertension 7 (1985) 244-252
30. Somanadhan B., Varughese G., Palpu P., Sreedharan R., Gudiksen L., et al. An ethnopharmacological survey for potential angiotensin converting enzyme inhibitors from India medicinal plants. J. Ethnopharmacol. 65 (1999) 103-112
31. Souccar, C., Cysneiros, R.M., Tanae, M.M., De Lima, T.C.M., Lima-Landman, M.T.R., Lapa, A.J., 2006. Inhibition of gastric acid secretion by a standardized aqueous extract of Cecropia glaziovii Sneth and underlying mechanism. Phytomedicine, submitted for publication.
32. Tanae, M.M., Cysneiros, R.M., Lima-Landman, M.T.R., Souccar, C., De Lima, T.C., Lapa, A.J., 2006. Chemical standardization of the aqueous extract of Cecropia glaziovii Sneth endowed with antihypertensive, bronchodilator, antiacid secretion and antidepressant-like activities. Phytomedicine, submitted for publication.
33. Ueno H., Horie S., Nishi Y., Shogawa H., Kawasaki M., et al. Chemical and pharmaceutical studies on medicinal plants in Paraguay. Geraniin an angiotensin-converting enzyme inhibitor from "Paparai mi", Phyllanthus niruri. J. Nat. Prod. 51 (1988) 357-359
34. Waeber B., Nussberger J., and Brunner H.R. Angiotensin-converting enzyme inhibitors in hypertension. In: Laragh J.H., and Brenner B.M. (Eds). Hypertension: Pathophysiology, Diagnosis and Management. second ed (1995), Raven Press, Ltda, NY 2861-2875
35. Wagner H. Leading structures of plant origin for drug development. J. Ethnopharmacol. 38 (1993) 105-112
36. Wagner H., and Elbl G. ACE - inhibitory procyanidins from Lespedeza capitata. Planta Med. 58 (1992) 297
37. Yamadaki, M., Shimoyama, A., 1993. Angiotensin-converting enzyme I inhibitor extraction from the Eucommia ulmoides leaves. Patent Jpn Kokai Tokkyo Koho JP 04368336 (92368336). (Chemical Abstract 118(15459c) 457.
38. Zaman M.A., Oparil S., and Calhoun D.A. Drugs targeting the renin-angiotensin-aldosterone system. Nat. Rev. Drug Discovery 1 (2002) 621-636