The benefits of CRT: Mechanical remodeling and beyond

PACE - Pacing and Clinical Electrophysiology

Volumn 30, Issue 5, 2007, Pages 587-590

  Hamdan, Mohamed H ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43;

ARRHYTHMOGENESIS; CARDIAC RESYNCHRONIZATION THERAPY; CONGESTIVE HEART FAILURE; DEFIBRILLATOR; EDITORIAL; ELECTROCARDIOGRAM; ELECTROSTIMULATION; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CONDUCTION DISTURBANCE; HEART MUSCLE POTENTIAL; HEART REPOLARIZATION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE CONDUCTION; HEART VENTRICLE PACING; HEART VENTRICLE REMODELING; HEART VENTRICLE TACHYCARDIA; HUMAN; NONHUMAN; PROTEIN EXPRESSION; QRS COMPLEX; QT DISPERSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYMPATHETIC TONE; THERAPY EFFECT;

CARDIAC PACING, ARTIFICIAL; ELECTRIC COUNTERSHOCK; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; HEART CONDUCTION SYSTEM; HEART FAILURE, CONGESTIVE; HUMANS; VENTRICULAR REMODELING;

EID: 34247517348     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2007.00716.x     Document Type: Editorial

References (32)

1. Cazeau S, Ritter P, Lazarus A, Gras D, Backdach H, Mundler O, Mugica J. Multisite pacing for end-stage heart failure: Early experience. Pacing Clin Electrophysiol 1996 19 : 1748 1757.
2. Cazeau S, Leclercq C, Lavergne T, Walker S, Varma C, Linde C, Garrigue S, et al. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med 2001 344 : 873 880.
3. Auricchio A, Stellbrink C, Block M, Sack S, Vogt J, Bakker P, Klein H, et al. Effect of pacing chamber and atrioventricular delay on acute systolic function of paced patients with congestive heart failure. The Pacing Therapies for Congestive Heart Failure Study Group. The Guidant Congestive Heart Failure Research Group. Circulation 1999 99 : 2993 3001.
4. Blanc JJ, Etienne Y, Gilard M, Mansourati J, Munier S, Boschat J, Benditt DG, et al. Evaluation of different ventricular pacing sites in patients with severe heart failure: Results of an acute hemodynamic study. Circulation 1997 96 : 3273 3277.
5. Kass DA, Chen CH, Curry C, Talbot M, Berger R, Fetics B, Nevo E. Improved left ventricular mechanics from acute VDD pacing in patients with dilated cardiomyopathy and ventricular conduction delay. Circulation 1999 99 : 1567 1573.
6. Kerwin WF, Botvinick EH, O'Connell JW, Merrick SH, DeMarco T, Chatterjee K, Scheibly K, et al. Ventricular contraction abnormalities in dilated cardiomyopathy: Effect of biventricular pacing to correct interventricular dyssynchrony. J Am Coll Cardiol 2000 35 : 1221 1227.
7. Janse MJ. Electrophysiological changes in heart failure and their relationship to arrhythmogenesis. Cardiovasc Res 2004 61 : 208 217.
8. Tomaselli GF, Zipes DP. What causes sudden death in heart failure? Circ Res 2004 95 : 754 763.
9. Poelzing S, Rosenbaum DS. Altered connexin43 expression produces arrhythmia substrate in heart failure. Am J Physiol Heart Circ Physiol 2004 287 : H1762 1770.
10. Li GR, Lau CP, Ducharme A, Tardif JC, Nattel S. Transmural action potential and ionic current remodeling in ventricles of failing canine hearts. Am J Physiol Heart Circ Physiol 2002 283 : H1031 1041.
11. Akar FG, Spragg DD, Tunin RS, Kass DA, Tomaselli GF. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circ Res 2004 95 : 717 725.
12. Spragg DD, Akar FG, Helm RH, Tunin RS, Tomaselli GF, Kass DA. Abnormal conduction and repolarization in late-activated myocardium of dyssynchronously contracting hearts. Cardiovasc Res 2005 67 : 77 86.
13. Yan GX, Shimizu W, Antzelevitch C. Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations. Circulation 1998 98 : 1921 1927.
14. Fish JM, Di Diego JM, Nesterenko V, Antzelevitch C. Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing. Circulation 2004 109 : 2136 2142.
15. Bai R, Yang XY, Song Y, Lin L, Lu JG, Ching CK, Pu J, et al. Impact of left ventricular epicardial and biventricular pacing on ventricular repolarization in normal-heart individuals and patients with congestive heart failure. Europace 2006 8 : 1002 1010.
16. Chalil S, Yousef ZR, Muyhaldeen SA, Smith RE, Jordan P, Gibbs CR, Leyva F. Pacing-induced increase in QT dispersion predicts sudden cardiac death following cardiac resynchronization therapy. J Am Coll Cardiol 2006 47 : 2486 2492.
17. van Huysduynen BH, Swenne CA, Bax JJ, Bleeker GB, Draisma HH, van Erven L, Molhoek SG, et al. Dispersion of repolarization in cardiac resynchronization therapy. Heart Rhythm 2005 2 : 1286 1293.
18. Santangelo L, Ammendola E, Russo V, Cavallaro C, Vecchione F, Garofalo S, D'Onofrio A, et al. Influence of biventricular pacing on myocardial dispersion of repolarization in dilated cardiomyopathy patients. Europace 2006 8 : 502 505.
19. Bortone A, Macia JC, Leclercq F, Pasquie JL. Monomorphic ventricular tachycardia induced by cardiac resynchronization therapy in patient with severe nonischemic dilated cardiomyopathy. Pacing Clin Electrophysiol 2006 29 : 327 330.
20. Di Cori A, Bongiorni MG, Arena G, Soldati E, Giannola G, Zucchelli G, Balbarini A. New-onset ventricular tachycardia after cardiac resynchronization therapy. J Interv Card Electrophysiol 2005 12 : 231 235.
21. Medina-Ravell VA, Lankipalli RS, Yan GX, Antzelevitch C, Medina-Malpica NA, Medina-Malpica OA, Droogan C, et al. Effect of epicardial or biventricular pacing to prolong QT interval and increase transmural dispersion of repolarization: Does resynchronization therapy pose a risk for patients predisposed to long QT or torsade de pointes? Circulation 2003 107 : 740 746.
22. Arya A, Haghjoo M, Dehghani MR, Alasti M, Alizadeh H, Kazemi B, Sadr-Ameli MA. Effect of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in patients with an implantable cardioverter- defibrillator. Heart Rhythm 2005 2 : 1094 1098.
23. Ermis C, Seutter R, Zhu AX, Benditt LC, VanHeel L, Sakaguchi S, Lurie KG, et al. Impact of upgrade to cardiac resynchronization therapy on ventricular arrhythmia frequency in patients with implantable cardioverter-defibrillators. J Am Coll Cardiol 2005 46 : 2258 2263.
24. Higgins SL, Yong P, Sheck D, McDaniel M, Bollinger F, Vadecha M, Desai S, et al. Biventricular pacing diminishes the need for implantable cardioverter defibrillator therapy. Ventak CHF Investigators. J Am Coll Cardiol 2000 36 : 824 827.
25. Kowal RC, Wasmund SL, Smith ML, Sharma N, Carayannopoulos GN, Le B, Cogan J, et al. Biventricular pacing reduces the induction of monomorphic ventricular tachycardia: A potential mechanism for arrhythmia suppression. Heart Rhythm 2004 1 : 295 300.
26. Walker S, Levy TM, Rex S, Brant S, Allen J, Ilsley CJ, Paul VE. Usefulness of suppression of ventricular arrhythmia by biventricular pacing in severe congestive cardiac failure. Am J Cardiol 2000 86 : 231 233.
27. Dizon J, Horn E, Neglia J, Medina N, Garan H. Loss of left bundle branch block following biventricular pacing therapy for heart failure: Evidence for electrical remodeling? J Interv Card Electrophysiol 2004 10 : 47 50.
28. Boriani G, Biffi M, Martignani C, Ziacchi M, Saporito D, Grigioni F, Domenichini G, et al. Electrocardiographic remodeling during cardiac resynchronization therapy. Int J Cardiol 2006 108 : 165 170.
29. Reckova M, Rosengarten C, deAlmeida A, Stanley CP, Wessels A, Gourdie RG, Thompson RP, et al. Hemodynamics is a key epigenetic factor in development of the cardiac conduction system. Circ Res 2003 93 : 77 85.
30. Grassi G, Vincenti A, Brambilla R, Trevano FQ, Dell'Oro R, Ciro A, Trocino G, et al. Sustained sympathoinhibitory effects of cardiac resynchronization therapy in severe heart failure. Hypertension 2004 44 : 727 731.
31. Hamdan MH, Barbera S, Kowal RC, Page RL, Ramaswamy K, Joglar JA, Karimkhani V, et al. Effects of resynchronization therapy on sympathetic activity in patients with depressed ejection fraction and intraventricular conduction delay due to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 2002 89 : 1047 1051.
32. Hamdan MH, Zagrodzky JD, Joglar JA, Sheehan CJ, Ramaswamy K, Erdner JF, Page RL, et al. Biventricular pacing decreases sympathetic activity compared with right ventricular pacing in patients with depressed ejection fraction. Circulation 2000 102 : 1027 1032.