Exploring GABAergic and dopaminergic effects in a minimal model of a medium spiny projection neuron

Neurocomputing

Volumn 70, Issue 10-12, 2007, Pages 1615-1618

  Samuelsson, Ebba ^a   Kotaleski, Jeanette H ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Dopamine; GABA; Medium spiny projection neuron; Striatum

Indexed keywords

AMINO ACIDS; BIOACTIVITY; BIOLOGICAL MEMBRANES; BRAIN; COGNITIVE SYSTEMS;

DOPAMINE-INDUCED BISTABILITY; GLUTAMATERGIC INPUT; MEDIUM SPINY PROJECTION NEURON;

NEURONS;

DOPAMINE; GLUTAMIC ACID;

ARTICLE; BASAL GANGLION; BRAIN NERVE CELL; COGNITION; CONDITIONING; CORPUS STRIATUM; DEPOLARIZATION; DOPAMINERGIC ACTIVITY; DOPAMINERGIC SYSTEM; GABAERGIC TRANSMISSION; HYPERPOLARIZATION; INTERNEURON; LOCOMOTION; MATHEMATICAL MODEL; MESENCEPHALON; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; REWARD;

EID: 34247513404     PISSN: 09252312     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neucom.2006.10.045     Document Type: Article

References (11)

1. Blackwell K.T., Czubayko U., and Plenz D. Quantitative estimate of synaptic inputs to striatal neurons during up and down states in vitro. J. Neurosci. 23 (2003) 9123-9132
2. Bracci E., and Panzeri S. Excitatory gabaergic effects in striatal projection neurons. J. Nerurophysiol. 95 (2006) 1285-1290
3. Gruber A.J., Solla S.A., James S.D., and Houk J.C. Modulation of striatal single units by expected reward: a spiny neuron model displaying dopamine-induced bistability. J. Neurophysiol. 90 (2003) 1095-1114
4. Kitano K., Câteau H., Kaneda K., Nambu A., Takada M., and Fukai T. Two-state membrane potential transitions of straiatal spiny neurons as evidenced by numerical simulations and electrophysiological recordings in awake monkeys. J. Neurosci. 22 (2002) 1-6
5. Koós T., and Tepper J.M. Inhibitory control of neostriatal projection neurons by gabaergic interneurons. Nat. Neurosci. 2 5 (1999) 467-472
6. Mallet N., Le Moine C., Charpier S., and Gonon F. Feedforward inhibitation of projection neurons by fast-spiking gaba interneurons in the rat striatum in vivo. J. Neurosci. 25 (2005) 3857-3869
7. Nicola S.M., Surmeier D.J., and Malenka R.C. Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens. Annu, Rev. Neurosci. 23 (2000) 185-215
8. Plenz D. When inhibitaion goes incognito: feedback interaction between spiny projection neurons in striatal function, Trends Neurosci. 26 (2003) 436-443
9. Wilson C.J., and Kawaguchi Y. Origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. J. Neurosci. 16 (1996) 2397-2410
10. Wolf J.A., Moyer J.T., Lazarewicz M.T., Contreras D., Benoit-Marand M., O'Donnell P., and Finkel L.H. Nmda/ampa ratio impacts state transitions and entrainment to oscillations in a computational model of the nuclear accumbens medium spiny projection neuron. J. Neurosci. 25 40 (2005) 9080-9095
11. XPP/XPPAUT, last visited 29 April 2005. URL: 〈http://www.math.pitt.edu/~bard/bardware/tut/start.html〉.