Pre- and postnatal FGF-2 both facilitate recovery and alter cortical morphology following early medial prefrontal cortical injury

Behavioural Brain Research

Volumn 180, Issue 1, 2007, Pages 18-27

  Comeau, Wendy L ^a   Hastings, Erica ^a   Kolb, Bryan ^a  

^a UNIVERSITY OF LETHBRIDGE   (Canada)

Author keywords

Basic fibroblast growth factor; Cortical development; FGF 2; Prefrontal cortex; Recovery of function

Indexed keywords

FIBROBLAST GROWTH FACTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN WEIGHT; CONTROLLED STUDY; FACILITATION; FEMALE; LIMB MOVEMENT; MALE; MORPHOLOGY; NONHUMAN; PERINATAL PERIOD; PREFRONTAL CORTEX; PRENATAL PERIOD; PRIORITY JOURNAL; RAT; TASK PERFORMANCE;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BRAIN INJURIES; FEMALE; FIBROBLAST GROWTH FACTOR 2; MAZE LEARNING; MOTOR SKILLS; ORGAN SIZE; PREFRONTAL CORTEX; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, LONG-EVANS; RECOVERY OF FUNCTION; SEX FACTORS;

EID: 34247506704     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2007.02.026     Document Type: Article

References (48)

1. Abe K., and Saito H. Effects of basic fibroblast growth factor on central nervous system functions. Pharmacol Res 43 (2001) 307-312
2. Chadi G., and Fuxe K. Analysis of trophic responses in lesioned brain: focus on basic fibroblast growth factor mechanisms. Braz J Med Biol Res 31 (1998) 231-241
3. Emoto N., Gonzalez A.M., Walicke P.A., Wado E., Simmons D.M., Shimasaki S., et al. Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain. Growth Factors 2 (1989) 21-29
4. Flores C., Rodaros D., and Stewart J. Long-lasting induction of astrocytic basic fibroblast growth factor by repeated injections of amphetamine: blockade by concurrent treatment with aglutamate antagonist. J Neurosci 18 (1998) 9547-9555
5. Fouad K., Monfils M.H., Driscoll I., and Vaverk R.B.K. FGF-2-induced recovery of corticospinal projections may support improvement from neonatal motor cortex injury. Soc Neurosci Abstr (2005) 835.9
6. Fumagalli F., Bedogni F., Slotkin T.A., Racagni G., and Riva M.A. Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress. Neurobiol Dis 20 (2005) 731-737
7. Ghosh A., and Greenberg M.E. Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis. Neuron 15 (1995) 89-103
8. Gibb R, Kolb B. Tactile stimulation of functional recovery after perinatal cortical damage is mediated by FGF-2, submitted for publication.
9. Gibb R., Wegenast W.A., and Kolb B. Intensity of maternal exercise during pregnancy predicts functional and anatomical outcome of offspring follwoing perinatal brain injury. Soc Neurosci Abstr (2005) 835.17
10. Goldman P.S., and Galkin T.W. Prenatal removal of frontal association cortex in the fetal rhesus monkey: anatomical and functional consequences in postnatal life. Brain Res 152 (1978) 451-485
11. Gomez-Pinilla F., and Cotman C.W. Transient lesion-induced increase in basic fibroblast growth factor and its receptor in layer VIb (Subplate cells) of the adult rat cerebral cortex. Neuroscience 49 (1992) 771-780
12. Gomez-Pinilla F., Lee J.W.K., and Cotman C.W. Distribution of basic fibroblast growth factor in the developing rat brain. Neuroscience 61 (1994) 911-923
13. Kennard M.A. Age and other factors in motor recovery from precentral lesion in monkeys. Am J Physiol 115 (1936) 138-146
14. Kennard M.A. Reorganization of motor function in the cerebral cortex of monkeys deprived of motor and premotor areas in infancy. J Neurophysiol 1 (1938) 477-496
15. Kirschner P.B., Henshaw R., Weise J., Trubetskoy V., Finklestein S., Schultz J.B., et al. Basic fibroblast growth factor protects against excitiotoxicity and chemical hypoxia in both neonatal and adult rats. J Cereb Blood Flow Metab 15 (1995) 619-623
16. Kiyota Y., Takami K., Iwane M., Shino A., Miyamoto M., Tsukuda R., et al. Increase in basic fibroblast growth factor-like immunoreactivity in rat brain after forebrain ischemia. Brain Res 545 (1991) 322-328
17. Kleim J.A., Barbay S., and Nudo R.J. Functional reorganization of the rat motor cortex following motor skill learning. J Neurophysiol 80 (1998) 3321-3325
18. Kolb B. Recovery from early cortical damage in rats. I. Differential behavioral and anatomical effects of frontal lesions at different ages of neural maturation. Behav Brain Res 25 (1987) 205-220
19. Kolb B. Brain Plasticity and Behavior (1995), Lawrence Erlbaum Associates, Mahwah
20. Kolb B. Overview of cortical plasticity and recovery from brain injury. Phys Med Rehabil Clin N Am 14 (2003) S7-S25
21. Kolb B., and Cioe J. Recovery from early cortical damage in rats. VIII. Earlier may be worse: behavioral dysfucntion and abnormal cerebral morphogenesis following perinatal frontal cortical lesions in the rat. Neuropharmacology 39 (2000) 756-764
22. Kolb B., Cioe J., and Muirhead D. Cerebral morphology and functional sparing after prenatal frontal cortex lesions in rats. Behav Brain Res 91 (1998) 143-155
23. Kolb B., and Gibb R. Anatomical correlates of behavioural change after neonatal prefrontal lesions in rats. Prog Brain Res 85 (1990) 241-255 [discussion 55-6]
24. Kolb B., and Gibb R. Sparing of function after neonatal frontal lesions correlates with increased cortical dendritic branching: a possible mechanism for the Kennard effect. Behav Brain Res 43 (1991) 51-56
25. Kolb B., and Gibb R. Early brain injury, plasticity, and behavior. In: Nelson C.A., and Luciana M. (Eds). Handbook of Developmental Cognitive Neuroscience (2001), The MIT Press, Cambridge 175-190
26. Kolb B., Gibb R., and Gorny G. Cortical plasticity and the development of behavior after early frontal cortical injury. Dev Neuropsychol 18 (2000) 423-444
27. Kolb B., Gibb R., Gorny G., and Whishaw I.Q. Possible regeneration of rat medial frontal cortex following neonatal frontal lesions. Behav Brain Res 91 (1998) 127-141
28. Kolb B., Gibb R., and van der Kooy D. Neonatal frontal cortical lesions in rats alter cortical structure and connectivity. Brain Res 645 (1994) 85-97
29. Kolb B., Pedersen B., Ballermann M., Gibb R., and Whishaw I.Q. Embryonic and postnatal injections of bromodeoxyuridine produce age-dependent morphological and behavioral abnormalities. J Neurosci 19 (1999) 2337-2346
30. Kolb B., Petrie B., and Cioe J. Recovery from early cortical damage in rats, VII. Compensation of the behavioural and anatomical effects of medial prefrontal lesions at different ages of neural maturation. Behav Brain Res 79 (1996) 1-13
31. Kolb B., and Whishaw I.Q. Neonatal frontal lesions in the rat: sparing of learned but not species-typical behavior in the presence of reduced brain weight and cortical thickness. J Comp Physiol Psychol 95 (1981) 863-879
32. Mattson M.P., and Cheng B. Growth factors protect neurons against excitotoxic/ischemic damage by stablizing calcium homeostasis. Stroke (1993) 24
33. Mattson M.P., and Scheff S.W. Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and inplication for therapy. J Neurotrauma 11 (1994) 3-33
34. McKenna J.E., Brown R.W.B.K., and Gibb R. The effects of prenatal nicotine exposure on recovery from perinatal frontal cortex lesions. Soc Neurosci Abstr (2000) 653.17
35. Monfils M.H., Driscoll I., Kamitakahara H., Wilson B., Flynn C., Teskey G.C., et al. FGF-2-induced cell proliferation stimulates anatomical, neurophysiological and functional recovery from neonatal motor cortex injury. Eur J Neurosci 24 (2006) 739-749
36. Monfils M.H., Driscoll I., Vandenberg P.M., Thomas N.J., Danka D., Kleim J.A., et al. Basic fibroblast growth factor stimulates functional recovery after neonatal lesions of motor cortex in rats. Neuroscience 134 (2005) 1-8
37. Morris R.G.M. Spatial localization does not require the presence of local cues. Learn Mem 12 (1981) 239-260
38. Qian X., Davis A.A., Goderie S.K., and Temple S. FGF2 concentration regulates the generation of neruons and glia from multipotent cortical stem cells. Neuron 18 (1997) 81-93
39. Riva M.A., and Mocchetti I. Developmental expression of basic fibroblast growth factor gene in rat brain. Dev Brain Res 62 (1991) 45-50
40. Vaccarino F.M. Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis. Nat Neurosci 2 (1999) 246-253
41. Villablanca J.R., Carlson-Kuhta P., Schmanke T.D., and Hovda D.A. A critical maturational period of reduced brain vulnerability to developmental injury. I. Behavioral studies in cats. Brain Res Dev Brain Res 105 (1998) 309-324
42. Villablanca J.R., Olmstead C.E., Levine M.S., and Marcus R.J. Effects of caudate nuclei or frontal cortical ablations in kittens: neurology and gross behavior. Exp Neurol 61 (1978) 615-634
43. Wagner J.P., Black I.B., and DiCicco-Bloom E. Stimulation of neonatal and adult neruogenesis by subcutaneous injections of basic fibroblast growth factor. J Neurosci 19 (1999) 6006-6016
44. Walicke P.A., and Baird A. Internalization and processing of basic fibroblast growth factor by neurons and astrocytes. J Neurosci 11 (1991) 2249-2258
45. Whishaw I.Q., O'Connor R.B., and Dunnett S.B. The contributions of motor cortex, nigrostriatal dopamine, and caudate-putamen to skilled forelimb use in the rat. Brain 109 (1986) 805-843
46. Whishaw I.Q., Pellis S.M., and Gorny B.P. Medial frontal cortex lesions impair the aiming component of rat reaching. Behav Brain Res 50 (1992) 93-104
47. Yamada K., Kinoshita A., and Kohmura E. Basic Fibroblast growth factor prevents thalamic degeneration after cortical infarction. J Cereb Blood Flow Metab 11 (1991) 472-478
48. Zilles K. The Cortex of the Rat: A Stereotaxic Atlas (1985), Springer-Verlag, Berlin, Heidelberg, New York, Toyko 121 pp.