Structure-activity relationships in the haemolytic activity and nephrotoxicity of derivatives of 1,2- and 1,4-naphthoquinone

Journal of Applied Toxicology

Volumn 27, Issue 3, 2007, Pages 262-269

  Munday, Rex ^a   Smith, Barry L ^a   Munday, Christine M ^a  

^a RUAKURA RESEARCH CENTRE   (New Zealand)

Author keywords

Haemolysis; Naphthoquinones; Nephrotoxicity; Structure activity relationships

Indexed keywords

1,2 NAPHTHOQUINONE DERIVATIVE; 1,4 NAPHTHOQUINONE; 2 AMINO 1,4 NAPHTHOQUINONE; LAWSONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; HEMOLYSIS; HEMOLYTIC ANEMIA; METHYLATION; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANEMIA, HEMOLYTIC; ANIMALS; CATALYSIS; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMOLYTIC AGENTS; KIDNEY; KIDNEY DISEASES; MOLECULAR STRUCTURE; NAD(P)H DEHYDROGENASE (QUINONE); NAPHTHOQUINONES; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; UREA;

ANIMALIA; RATTUS;

EID: 34247503841     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1206     Document Type: Article

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