Mapping of possible prion protein self-interaction domains using peptide arrays

BMC Biochemistry

Volumn 8, Issue , 2007, Pages

  Rigter, Alan ^a   Langeveld, Jan P M ^a   Timmers Parohi, Drophatie ^b   Jacobs, Jorg G ^a   Moonen, Peter L J M ^a   Bossers, Alex ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b Pepscan Systems   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; MALTOSE BINDING PROTEIN; PRION PROTEIN; CARRIER PROTEIN; HYBRID PROTEIN; MALTOSE-BINDING PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBODY SPECIFICITY; ARTICLE; DISEASE PREDISPOSITION; GENETIC POLYMORPHISM; MICROARRAY ANALYSIS; MOLECULAR PROBE; PEPTIDE MAPPING; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SCRAPIE; STRAIN DIFFERENCE; WESTERN BLOTTING; ANIMAL; CATTLE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; PROTEIN MICROARRAY; PROTEIN TERTIARY STRUCTURE; SHEEP;

BOVINAE; OVIS; OVIS ARIES;

ANIMALS; CARRIER PROTEINS; CATTLE; POLYMORPHISM, GENETIC; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PRPC PROTEINS; RECOMBINANT FUSION PROTEINS; SHEEP;

EID: 34247501644     PISSN: None     EISSN: 14712091     Source Type: Journal    
DOI: 10.1186/1471-2091-8-6     Document Type: Article

References (52)

1. Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment. SJ DeArmond SB Prusiner, Clin Lab Med 2003 23 1 1 41 10.1016/S0272-2712(02)00041-0 12733423
2. In vitro conversion of normal prion protein into pathologic isoforms. A Bossers A Rigter R de Vries MA Smits, Clin Lab Med 2003 23 1 227 247 10.1016/S0272-2712(02)00063-X 12733434
3. Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms. A Bossers P Belt GJ Raymond B Caughey R de Vries MA Smits, Proc Natl Acad Sci USA 1997 94 10 4931 4936 9144167 10.1073/pnas.94.10.4931
4. Molecular assessment of the potential transmissibilities of BSE and scrapie to humans. GJ Raymond J Hope DA Kocisko SA Priola LD Raymond A Bossers J Ironside RG Will SG Chen RB Petersen, Nature 1997 388 6639 285 288 10.1038/40876 9230438
5. Prion Disease: Susceptibility and Transmissibility; In vivo and in vitro studies with sheep scrapie. A Bossers, PhD thesis, University of Utrecht 1999
6. Susceptibility of sheep for scrapie as assessed by in vitro conversion of nine naturally occurring variants of PrP. A Bossers R de Vries MA Smits, J Virol 2000 74 3 1407 1414 10627551 10.1128/JVI.74.3.1407-1414.2000
7. Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease. GJ Raymond A Bossers LD Raymond KI O'Rourke LE McHolland PK Bryant 3rd MW Miller ES Williams M Smits B Caughey, Embo J 2000 19 17 4425 4430 10970836 10.1093/emboj/19.17.4425
8. Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier. DA Kocisko SA Priola GJ Raymond B Chesebro PT Lansbury Jr B Caughey, Proc Natl Acad Sci USA 1995 92 9 3923 3927 7732006 10.1073/pnas.92.9.3923
9. In situ formation of protease-resistant prion protein in transmissible spongiform encephalopathy-infected brain slices. RA Bessen GJ Raymond B Caughey, J Biol Chem 1997 272 24 15227 15231 10.1074/jbc.272.24.15227 9182546
10. Multiplicative genetic effects in scrapie disease susceptibility. MA Dubois P Sabatier B Durand D Calavas C Ducrot K Chalvet-Monfray, C R Biol 2002 325 5 565 570 10.1016/S1631-0691(02)01465-8 12187642
11. Influence of the prion protein gene, Prnp, on scrapie susceptibility in sheep. MA Tranulis, Apmis 2002 110 1 33 43 10.1034/j.1600-0463.2002.100105.x 12064254
12. PrP polymorphisms tightly control sheep prion replication in cultured cells. E Sabuncu S Petit A Le Dur T Lan Lai JL Vilotte H Laude D Vilette, J Virol 2003 77 4 2696 2700 12552009 10.1128/JVI.77.4.2696-2700.2003
13. Sheep scrapie susceptibility-linked polymorphisms do not modulate the initial binding of cellular to disease-associated prion protein prior to conversion. A Rigter A Bossers, J Gen Virol 2005 86 Pt 9 2627 2634 10.1099/vir.0.80901-0 16099922
14. Overexpression of nonconvertible PrPc delta114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation. C Holscher H Delius A Burkle, J Virol 1998 72 2 1153 1159 9445012
15. Inhibition of interactions and interconversions of prion protein isoforms by peptide fragments from the C-terminal folded domain. M Horiuchi GS Baron LW Xiong B Caughey, J Biol Chem 2001 276 18 15489 15497 10.1074/jbc.M100288200 11279046
16. A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. D Peretz RA Williamson Y Matsunaga H Serban C Pinilla RB Bastidas R Rozenshteyn TL James RA Houghten FE Cohen, J Mol Biol 1997 273 3 614 622 10.1006/jmbi.1997.1328 9356250
17. Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides. J Chabry B Caughey B Chesebro, J Biol Chem 1998 273 21 13203 13207 10.1074/jbc.273.21.13203 9582363
18. Prion (PrPSc)-specific epitope defined by a monoclonal antibody. C Korth B Stierli P Streit M Moser O Schaller R Fischer W Schulz-Schaeffer H Kretzschmar A Raeber U Braun, Nature 1997 390 6655 74 77 10.1038/36337 9363892
19. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. D Peretz RA Williamson K Kaneko J Vergara E Leclerc G Schmitt-Ulms IR Mehlhorn G Legname MR Wormald PM Rudd, Nature 2001 412 6848 739 743 10.1038/35089090 11507642
20. Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes. M Scott D Groth D Foster M Torchia SL Yang SJ DeArmond SB Prusiner, Cell 1993 73 5 979 988 10.1016/0092-8674(93)90275-U 8098995
21. A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells. SA Priola B Chesebro, J Virol 1995 69 12 7754 7758 7494285
22. Glycosylation influences cross-species formation of protease-resistant prion protein. SA Priola VA Lawson, Embo J 2001 20 23 6692 6699 11726505 10.1093/emboj/20.23.6692
23. Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. M Enari E Flechsig C Weissmann, Proc Natl Acad Sci USA 2001 98 16 9295 9299 11470893 10.1073/pnas.151242598
24. Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies. FL Heppner C Musahl I Arrighi MA Klein T Rulicke B Oesch RM Zinkernagel U Kalinke A Aguzzi, Science 2001 294 5540 178 182 10.1126/science.1063093 11546838
25. PrPSc binding antibodies are potent inhibitors of prion replication in cell lines. V Beringue D Vilette G Mallinson F Archer M Kaisar M Tayebi GS Jackson AR Clarke H Laude J Collinge, J Biol Chem 2004 279 38 39671 39676 10.1074/jbc.M402270200 15133046
26. Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation. V Perrier J Solassol C Crozet Y Frobert C Mourton-Gilles J Grassi S Lehmann, J Neurochem 2004 89 2 454 463 10.1111/j.1471-4159.2004.02356.x 15056288
27. Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity. M Gasset MA Baldwin RJ Fletterick SB Prusiner, Proc Natl Acad Sci USA 1993 90 1 1 5 8419912 10.1073/pnas.90.1.1
28. Toward Molecular Dissection of PrPC-PrPSc Interactions. L Solforosi A Bellon M Schaller JT Cruite GC Abalos RA Williamson, J Biol Chem 2007 282 10 7465 7471 10.1074/jbc.M610051200 17218310
29. H-Type Bovine Spongiform Encephalopathy. A-G Biacabe JG Jacobs A Bencsik JPM Langeveld TGM Baron, Prion 2007
30. Immunohistochemical distinction between preclinical bovine spongiform encephalopathy and scrapie infection in sheep. CM Thuring LJ van Keulen JP Langeveld ME Vromans FG van Zijderveld T Sweeney, J Comp Pathol 2005 132 1 59 69 10.1016/j.jcpa.2004.06.004 15629480
31. Amyloidogenic unfolding intermediates differentiate sheep prion protein variants. H Rezaei Y Choiset F Eghiaian E Treguer P Mentre P Debey J Grosclaude T Haertle, J Mol Biol 2002 322 4 799 814 10.1016/S0022-2836(02)00856-2 12270715
32. NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231). R Riek S Hornemann G Wider R Glockshuber K Wuthrich, FEBS Lett 1997 413 282 288 10.1016/S0014-5793(97)00920-4 9280298
33. Amino acid properties and consequences of substitutions. MJ Betts RB Russel, Bioinformatics for Geneticists John Wiley & sons, Barns MR, Gray IC, 2003
34. Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc. G Moroncini N Kanu L Solforosi G Abalos GC Telling M Head J Ironside JP Brockes DR Burton RA Williamson, Proc Natl Acad Sci USA 2004 101 28 10404 10409 15240877 10.1073/pnas.0403522101
35. The emerging principles of Mammalian prion propagation and transmissibility barriers: insight from studies in vitro. WK Surewicz EM Jones AC Apetri, Acc Chem Res 2006 39 9 654 662 10.1021/ar050226c 16981682
36. The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPSc. EM Norstrom JA Mastrianni, J Virol 2006 80 17 8521 8529 16912302 10.1128/JVI.00366-06
37. A prion protein epitope selective for the pathologically misfolded conformation. E Paramithiotis M Pinard T Lawton S LaBoissiere VL Leathers WQ Zou LA Estey J Lamontagne MT Lehto LH Kondejewski, Nat Med 2003 9 7 893 899 10.1038/nm883 12778138
38. Two-rung Model of a Left-handed beta-Helix for Prions Explains Species Barrier and Strain Variation in Transmissible Spongiform Encephalopathies. JP Langedijk G Fuentes R Boshuizen AM Bonvin, J Mol Biol 2006 360 4 907 920 10.1016/j.jmb.2006.05.042 16782127
39. Identification of an epitope in the C terminus of normal prion protein whose expression is modulated by binding events in the N terminus. R Li T Liu BS Wong T Pan M Morillas W Swietnicki K O'Rourke P Gambetti WK Surewicz MS Sy, J Mol Biol 2000 301 3 567 573 10.1006/jmbi.2000.3986 10966770
40. Structural studies of the scrapie prion protein by electron crystallography. H Wille MD Michelitsch V Guenebaut S Supattapone A Serban FE Cohen DA Agard SB Prusiner, Proc Natl Acad Sci USA 2002 99 6 3563 3568 11891310 10.1073/pnas.052703499
41. Evidence for assembly of prions with left-handed beta-helices into trimers. C Govaerts H Wille SB Prusiner FE Cohen, Proc Natl Acad Sci USA 2004 101 22 8342 8347 15155909 10.1073/pnas.0402254101
42. Prion protein glycosylation. VA Lawson SJ Collins CL Masters AF Hill, J Neurochem 2005 93 4 793 801 10.1111/j.1471-4159.2005.03104.x 15857383
43. Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon. W Goldmann N Hunter T Martin M Dawson J Hope, J Gen Virol 1991 72 Pt 1 201 204 1671225
44. Mapping of a discontinuous and highly conformational binding site on follicle stimulating hormone subunit-beta (FSH-beta) using domain Scan and Matrix Scan technology. P Timmerman E Van Dijk W Puijk W Schaaper J Slootstra SJ Carlisle J Coley S Eida M Gani T Hunt, Mol Divers 2004 8 2 61 77 10.1023/B:MODI.0000025650.94399.bb 15209158
45. An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. P Piccardo JP Langeveld AF Hill SR Dlouhy K Young G Giaccone G Rossi M Bugiani O Bugiani RH Meloen, Am J Pathol 1998 152 6 1415 1420 9626045
46. Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid. HM Geysen RH Meloen SJ Barteling, Proc Natl Acad Sci USA 1984 81 13 3998 4002 6204335 10.1073/pnas.81.13.3998
47. Rapid and discriminatory diagnosis of scrapie and BSE in retro-pharyngeal lymph nodes of sheep. JP Langeveld JG Jacobs JH Erkens A Bossers FG van Zijderveld LJ van Keulen, BMC Vet Res 2006 2 19 16764717 10.1186/1746-6148-2-19
48. Immunohistochemical detection and localization of prion protein in brain tissue of sheep with natural scrapie. LJ van Keulen BE Schreuder RH Meloen M Poelen-van den Berg G Mooij-Harkes ME Vromans JP Langeveld, Vet Pathol 1995 32 3 299 308 7604497
49. PrP genotype contributes to determining survival times of sheep with natural scrapie. A Bossers BE Schreuder IH Muileman PB Belt MA Smits, J Gen Virol 1996 77 Pt 10 2669 2673 8887505
50. Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state. B Caughey DA Kocisko GJ Raymond PT Lansbury Jr, Chem Biol 1995 2 12 807 817 10.1016/1074-5521(95)90087-X 8807814
51. Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. C Feraudet N Morel S Simon H Volland Y Frobert C Creminon D Vilette S Lehmann J Grassi, J Biol Chem 2005 280 12 11247 11258 10.1074/jbc.M407006200 15618225
52. Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein. CM Thuring JH Erkens JG Jacobs A Bossers LJ Van Keulen GJ Garssen FG Van Zijderveld SJ Ryder MH Groschup T Sweeney, J Clin Microbiol 2004 42 3 972 980 15004040 10.1128/JCM.42.3.972-980.2004