Determination of the antidepressant paroxetine and its three main metabolites in human plasma by liquid chromatography with fluorescence detection

Analytica Chimica Acta

Volumn 591, Issue 2, 2007, Pages 141-147

  Mandrioli, Roberto ^a   Mercolini, Laura ^a   Ferranti, Anna ^a   Furlanetto, Sandra ^b   Boncompagni, Giancarlo ^c   Raggi, Maria Augusta ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Fluorescence detection; High performance liquid chromatography; Human plasma; Metabolites; Paroxetine; Solid phase extraction

Indexed keywords

ANTIDEPRESSANT PAROXETINE; FLUORESCENCE DETECTION; PAROXETINE; SOLID PHASE EXTRACTION;

FLUORESCENCE SPECTROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES; PHASE SEPARATION; PLASMA (HUMAN);

DRUG PRODUCTS;

3 HYDROXYMETHYL 4 (4 FLUOROPHENYL)PIPERIDINE; 4 (4 FLUOROPHENYL) 3 (3 HYDROXY 4 METHOXYPHENOXYMETHYL)PIPERIDINE; 4 (4 FLUOROPHENYL) 3 (4 HYDROXY 3 METHOXYPHENOXYMETHYL)PIPERIDINE; ACETONITRILE; ANTIDEPRESSANT AGENT; IMIPRAMINE; PAROXETINE; PHOSPHATE; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; CALIBRATION; DEPRESSION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID; MONOTHERAPY; PH; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; STANDARD;

ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEPRESSION; FLUORESCENCE; HUMANS; PAROXETINE; REPRODUCIBILITY OF RESULTS;

EID: 34247468859     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2007.03.073     Document Type: Article

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