Staurosporine differentiation of NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells induces selectivity of NPFF activity towards opioid receptors

Peptides

Volumn 28, Issue 5, 2007, Pages 1125-1128

  Mollereau, Catherine ^a   Zajac, Jean Marie ^a   Roumy, Michel ^a  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CALCIUM; CLONIDINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MU OPIATE RECEPTOR; NEUROPEPTIDE FF; NEUROPEPTIDE FF2 RECEPTOR; NUCLEAR FACTOR Y; OPIATE RECEPTOR; RECEPTOR PROTEIN; STAUROSPORINE; UNCLASSIFIED DRUG; NEUROPEPTIDE FF RECEPTOR; NEUROPEPTIDE FF, TYR(1) N METHYL PHE(3); NEUROPEPTIDE FF, TYR(1)-N-METHYL-PHE(3)-; NEUROPEPTIDE RECEPTOR; NEUROPEPTIDE Y; OLIGOPEPTIDE; PHENYLALANYL LEUCYL PHENYLALANYL GLUTAMINYL PROLYL GLUTAMINYL ARGINYL PHENYLALANINAMIDE; PHENYLALANYL-LEUCYL-PHENYLALANYL-GLUTAMINYL-PROLYL-GLUTAMINYL-ARGINYL-PHENYLALANINAMIDE;

ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; HUMAN; HUMAN CELL; NEURITE; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL MEMBRANE; DRUG EFFECT; GENETICS; METABOLISM; NEUROBLASTOMA; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

CALCIUM; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MEMBRANE; CLONIDINE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; HUMANS; NEUROBLASTOMA; NEUROPEPTIDE Y; OLIGOPEPTIDES; RECEPTORS, NEUROPEPTIDE; RECEPTORS, OPIOID; STAUROSPORINE;

EID: 34247467544     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.03.001     Document Type: Article

References (15)

1. Jalava A., Akerman K., and Heikkila J. Protein kinase inhibitor, staurosporine, induces a mature neuronal phenotype in SH-SY5Y human neuroblastoma cells through an alpha-, beta-, and zeta-protein kinase C-independent pathway. J Cell Physiol 155 (1993) 301-312
2. Jalava A., Heikkila J., Lintunen M., Akerman K., and Pahlman S. Staurosporine induces a neuronal phenotype in SH-SY5Y human neuroblastoma cells that resembles that induced by the phorbol ester 12-O-tetradecanoyl phorbol-13 acetate (TPA). FEBS Lett 300 (1992) 114-118
3. Kennedy C., and Henderson G. Mu-opioid receptor inhibition of calcium current: development of homologous tolerance in single SH-SY5Y cells after chronic exposure to morphine in vitro. Mol Pharmacol 40 (1991) 1000-1005
4. Kersante F., Mollereau C., Zajac J.M., and Roumy M. Anti-opioid activities of NPFF(1) receptors in a SH-SY5Y model. Peptides 27 (2006) 980-989
5. 2+ channel currents in human neuroblastoma (SH-SY5Y) cells by neuropeptide Y and a novel cyclic neuropeptide Y analogue. Neuropharmacology 34 (1995) 1507-1514
6. Miller R.J. Presynaptic receptors. Annu Rev Pharmacol Toxicol 38 (1998) 201-227
7. Mollereau C., Mazarguil H., Zajac J.-M., and Roumy M. NPFF analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells. Mol Pharmacol 67 (2005) 965-975
8. 2+ channel currents in human neuroblastoma (SH-SY5Y) cells by muscarine via stimulation of M3 receptors. Neuropharmacology 34 (1995) 319-326
9. Roumy M., Lorenzo C., Mazeres S., Bouchet S., Zajac J.-M., and Mollereau C. Physical association between neuropeptide FF (NPFF) and mu-opioid (MOP) receptors as possible molecular basis for anti-opioid activity. J Biol Chem 282 (2007) 8332-8342
10. Roumy M., and Zajac J.-M. Neuropeptide FF, pain and analgesia. Eur J Pharmacol 345 (1998) 1-11
11. Roumy M., and Zajac J.-M. Neuropeptide FF selectively attenuates the effects of nociceptin on acutely dissociated neurons of the rat dorsal raphe nucleus. Brain Res 845 (1999) 208-214
12. Seward E., Hammond C., and Henderson G. Mu-opioid-receptor-mediated inhibition of the N-type calcium-channel current. Proc R Soc Lond B Biol Sci 244 (1991) 129-135
13. Toselli M., Perin P., and Taglietti V. Muscarine inhibits omega-conotoxin-sensitive calcium channels in a voltage- and time-dependent mode in the human neuroblastoma cell line SH-SY5Y. J Neurophysiol 74 (1995) 1730-1741
14. Toselli M., Tosetti P., and Taglietti V. Mu and delta opioid receptor activation inhibits omega-conotoxin- sensitive calcium channels in a voltage- and time-dependent mode in the human neuroblastoma cell line SH-SY5Y. Pflugers Arch 433 (1997) 587-596
15. Zajac J.-M. Neuropeptide FF: new molecular insights. Trends Pharmacol Sci 22 (2001) 63