A randomized prospective study on the use of 2 g-IVIG or 1 g-IVIG as therapy for Kawasaki disease

European Journal of Pediatrics

Volumn 166, Issue 6, 2007, Pages 565-571

  Sakata, Koichi ^a   Hamaoka, Kenji ^a   Ozawa, Sei Ichiro ^a   Niboshi, Ayumi ^a   Yoshihara, Takao ^a   Nishiki, Tesuo ^a   Nakagawa, Yumi ^a   Kazuta, Kikuko ^a   Morimoto, Yoshiko ^a   Kamiya, Yasutaka ^a   Yamamoto, Toru ^a   Horii, Yoshihiro ^a   Kido, Sachiko ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cost; Discriminate analysis; Immune globulin; Kawasaki disease; Resistance

Indexed keywords

ACETYLSALICYLIC ACID; FLURBIPROFEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; SULFONATED IMMUNOGLOBULIN;

ANEURYSM; ARTERY LESION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DILATATION; CORONARY ARTERY DISEASE; COST CONTROL; DISCRIMINANT ANALYSIS; DRUG COST; DRUG DOSE COMPARISON; DRUG DOSE REDUCTION; DRUG EFFICACY; FEMALE; FEVER; HOSPITAL ADMISSION; HUMAN; INCIDENCE; INFANT; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; TREATMENT OUTCOME;

CHILD; CHILD, PRESCHOOL; CORONARY DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEES, PHARMACEUTICAL; FEMALE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; INFANT; MALE; MUCOCUTANEOUS LYMPH NODE SYNDROME; PROSPECTIVE STUDIES;

EID: 34247401244     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-006-0280-3     Document Type: Article

References (15)

1. Fasano MB (1995) Risks and benefits of intravenous immunoglobulin treatment in children. Curr Opin Pediatr 7:688-694
2. Hashino K, Ishii M, Iemura M, Akagi T, Kato H (2001) Retreatment for immune globulin-resistant Kawasaki disease: a comparative study of additional immune globulin and steroid pulse therapy. Pediatr Int 43:211-217
3. Jibiki T, Terai M, Kurosaki T, Nakajima H, Suzuki K, Inomata H, Terashima I, Honda T, Yasukawa K, Hamada H, Kohno Y (2004) Efficacy of intravenous immune globulin therapy combined with dexamethasone for the initial treatment of acute Kawasaki disease. Eur J Pediatr 163:229-233
4. Lang B, Duffy CM (2002) Controversies in the management of Kawasaki disease. Best Pract Res Clin Rheumatol 16:427-442
5. Lee MS, An SY, Jang GC and Kim DS (2002) A case of intravenous immunoglobulin-resistant Kawasaki disease treated with methotrexate. Yonsei Med J 43:527-532
6. Miura M, Ohki H, Tsuchihashi T, Yamagishi H, Katada Y, Yamada K, Yamashita Y, Sugaya A, Komiyama O, Shiro H (2004) Coronary risk factors in Kawasaki disease treated with additional gammaglobulin. Arch Dis Child 89:776-780
7. Mori M, Tomono N, Yokota S (1995) Coronary arteritis of Kawasaki disease unresponsive to high-dose intravenous gamma-globulin successfully treated with plasmapheresis. Nihon Rinsho Meneki Gakkai Kaishi 18:282-288
8. Newburger JW, Takahashi M, Beiser AS, Burns JC, Bastian J, Chung KJ, Colan SD, Duffy CE, Fulton DR, Glode MP (1991) A single intravenous infusion of gamma globulin as compared with four infusions in the treatment of acute Kawasaki syndrome. N Engl J Med 324:1633-1639
9. Oates-Whitehead RM, Baumer JH, Haines L, Love S, Maconochie IK, Gupta A, Roman K, Dua JS and Flynn I (2003) Intravenous immunoglobulin for the treatment of Kawasaki disease in children (Cochrane Review). Cochrane Database Syst Rev 4: CD004000 (DOI 10.1002/14651858.CD004000)
10. Onouchi Z, Kawasaki T (1999) Overview of pharmacological treatment of Kawasaki disease. Drugs 58:813-822
11. Redwan EL (2002) Biochemical and immunological properties of four intravenous Immunoglobulin G preparations. Hum Antibodies 11:79-84
12. Sato N, Sugimura T, Akagi T, Yamakawa R, Hashino K, Eto G, Iemura M, Ishii M, Kato H (1999) Selective high dose gamma-globulin treatment in Kawasaki disease: assessment of clinical aspects and cost effectiveness. Pediatr Int 41:1-7
13. Shulman ST, Rowley AH (2004) Advances in Kawasaki disease. Eur J Pediatr 163:285-291
14. Suto F, Sakata K, Kamiya Y, Hamaoka K, Onouchi Z, Tanaka T, Nukina S (1998) Additional gamma-globulin therapy (IVGG) for the patients of Kawasaki disease who are resistant to first IVGG. Prog Med 18:1649-1651
15. Suto F, Sato H, Yoiyama K, Ozawa S, Teramachi S, Nakagawa Y, Kido S, Sakata K, Kamiya Y, Itoi T, Hamaoka K, Onouchi Z (1997) Predictors of coronary artery lesions after intravenous gamma-globulin therapy in Kawasaki disease. Prog Med 17:1820-1827