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Volumn 17, Issue 4, 2007, Pages 295-297

Shp2, a novel oncogenic tyrosine phosphatase and potential therapeutic target for human leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE, NON RECEPTOR TYPE 11; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

EID: 34247379423     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2007.18     Document Type: Note
Times cited : (15)

References (10)
  • 1
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    • The role of Shp2 (PTPN11) in cancer
    • Mohi MG, Neel BG. The role of Shp2 (PTPN11) in cancer. Curr Opin Genet Dev 2007; 17:23-30.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 23-30
    • Mohi, M.G.1    Neel, B.G.2
  • 2
    • 33846854905 scopus 로고    scopus 로고
    • PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase
    • Chan RJ, Feng GS. PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase. Blood 2007; 109:862-7.
    • (2007) Blood , vol.109 , pp. 862-867
    • Chan, R.J.1    Feng, G.S.2
  • 4
    • 27644483149 scopus 로고    scopus 로고
    • Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia
    • Xu R, Yu Y, Zheng S, et al. Overexpression of Shp2 tyrosine phosphatase is implicated in leukemogenesis in adult human leukemia. Blood 2005; 106:3142-9.
    • (2005) Blood , vol.106 , pp. 3142-3149
    • Xu, R.1    Yu, Y.2    Zheng, S.3
  • 5
    • 33846223147 scopus 로고    scopus 로고
    • SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl
    • Chen J, Yu WM, Daino H, et al. SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl. Blood 2007; 109:778-85.
    • (2007) Blood , vol.109 , pp. 778-785
    • Chen, J.1    Yu, W.M.2    Daino, H.3
  • 6
    • 33645745233 scopus 로고    scopus 로고
    • Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML)
    • Scherr M, Chaturvedi A, Battmer K, et al. Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML). Blood 2006; 107:3279-87.
    • (2006) Blood , vol.107 , pp. 3279-3287
    • Scherr, M.1    Chaturvedi, A.2    Battmer, K.3
  • 7
    • 33747788689 scopus 로고    scopus 로고
    • Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein
    • Huang W, Saberwal G, Horvath E, et al. Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein. Mol Cell Biol 2006; 26:6311-32.
    • (2006) Mol Cell Biol , vol.26 , pp. 6311-6332
    • Huang, W.1    Saberwal, G.2    Horvath, E.3
  • 8
    • 0030663034 scopus 로고    scopus 로고
    • The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors
    • Sattler M, Salgia R, Shrikhande G, et al. The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors. Oncogene 1997; 15:2379-84.
    • (1997) Oncogene , vol.15 , pp. 2379-2384
    • Sattler, M.1    Salgia, R.2    Shrikhande, G.3
  • 9
    • 0038278866 scopus 로고    scopus 로고
    • Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
    • Tartaglia M, Niemeyer CM, Fragale A, et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nat Genet 2003; 34:148-50.
    • (2003) Nat Genet , vol.34 , pp. 148-150
    • Tartaglia, M.1    Niemeyer, C.M.2    Fragale, A.3
  • 10
    • 33746217416 scopus 로고    scopus 로고
    • Discovery of a novel shp2 protein tyrosine phosphatase inhibitor
    • Chen L, Sung SS, Yip ML, et al. Discovery of a novel shp2 protein tyrosine phosphatase inhibitor. Mol Pharmacol 2006; 70:562-70.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.