Cellular sites of Drosophila NinaB and NinaD activity in vitamin A metabolism

Molecular and Cellular Neuroscience

Volumn 35, Issue 1, 2007, Pages 49-56

  Yang, Jing ^a   O'Tousa, Joseph E ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

Carotene oxygenase; Drosophila vision; Retinal; Type B scavenger receptor; Vitamin A

Indexed keywords

BETA CAROTENE; CAROTENOID; RETINAL; RETINOL; RHODOPSIN;

ANIMAL TISSUE; ARTICLE; BIOGENESIS; BRAIN; CONTROLLED STUDY; DEVELOPMENT; DROSOPHILA; EMBRYO; GENE; GENE EXPRESSION; IN SITU HYBRIDIZATION; NINAB GENE; NINAD GENE; NONHUMAN; PRIORITY JOURNAL; RETINA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VITAMIN METABOLISM;

AGE FACTORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BETA CAROTENE; BETA-CAROTENE 15,15'-MONOOXYGENASE; BRAIN; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GANGLIA, INVERTEBRATE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LARVA; OPTIC LOBE; RECEPTORS, IMMUNOLOGIC; RETINALDEHYDE; VITAMIN A;

EID: 34247364623     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2007.02.001     Document Type: Article

References (28)

1. Ahmad S.T., Joyce M.V., Boggess B., and O'Tousa J.E. The role of Drosophila ninaG oxidoreductase in visual pigment chromophore biogenesis. J. Biol. Chem. 281 (2006) 9205-9209
2. Bhatti R.A., Yu S., Boulanger A., Fariss R.N., Guo Y., Bernstein S.L., Gentleman S., and Redmond T.M. Expression of beta-carotene 15,15′ monooxygenase in retina and RPE-choroid. Invest. Ophthalmol. Visual Sci. 44 (2003) 44-49
3. Brand A.H., and Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118 (1993) 401-415
4. Giovannucci D.R., and Stephenson R.S. Identification and distribution of dietary precursors of the Drosophila visual pigment chromophore: analysis of carotenoids in wild type and ninaD mutants by HPLC. Vision Res. 39 (1999) 219-229
5. Gu G., Yang J., Mitchell K.A., and O'Tousa J.E. Drosophila ninaB and ninaD act outside of retina to produce rhodopsin chromophore. J. Biol. Chem. 279 (2004) 18608-18613
6. Hassan B.A., Bermingham N.A., He Y., Sun Y., Jan Y.N., Zoghbi H.Y., and Bellen H.J. atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain. Neuron 25 (2000) 549-561
7. Kiefer C., Sumser E., Wernet M.F., and Von Lintig J. A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 10581-10586
8. Lindqvist A., and Andersson S. Biochemical properties of purified recombinant human beta-carotene 15,15′-monooxygenase. J. Biol. Chem. 277 (2002) 23942-23948
9. Livera G., Rouiller-Fabre V., and Habert R. Retinoid receptors involved in the effects of retinoic acid on rat testis development. Biol. Reprod. 64 (2001) 1307-1314
10. Maden M., and Hind M. Retinoic acid, a regeneration-inducing molecule. Dev. Dyn. 226 (2003) 237-244
11. Mark M., Ghyselinck N.B., and Chambon P. Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis. Annu. Rev. Pharmacol. Toxicol. 46 (2006) 451-480
12. Paik J., During A., Harrison E.H., Mendelsohn C.L., Lai K., and Blaner W.S. Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids. J. Biol. Chem. 276 (2001) 32160-32168
13. Pak W.L. Drosophila in vision research. The Friedenwald Lecture. Invest. Ophthalmol. Visual Sci. 36 (1995) 2340-2357
14. Pfahl M., and Chytil F. Regulation of metabolism by retinoic acid and its nuclear receptors. Annu. Rev. Nutr. 16 (1996) 257-283
15. Redmond T.M., Gentleman S., Duncan T., Yu S., Wiggert B., Gantt E., and Cunningham Jr. F.X. Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15′-dioxygenase. J. Biol. Chem. 276 (2001) 6560-6565
16. Sarfare S., Ahmad S.T., Joyce M.V., Boggess B., and O'Tousa J.E. The Drosophila ninaG oxidoreductase acts in visual pigment chromophore production. J. Biol. Chem. 280 (2005) 11895-11901
17. Seddon J.M., Ajani U.A., Sperduto R.D., Hiller R., Blair N., Burton T.C., Farber M.D., Gragoudas E.S., Haller J., Miller D.T., et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-control Study Group. JAMA 272 (1994) 1413-1420
18. Spradling A.C. P element-mediated transformation. In: Roberts D.B. (Ed). Drosophila, A Practical Approach (1986), IRL Press Limited, Oxford, England 175-196
19. Stahl W., and Sies H. Bioactivity and protective effects of natural carotenoids. Biochim. Biophys. Acta 1740 (2005) 101-107
20. Stephenson R.S., O'Tousa J., Scavarda N.J., Randall L.L., and Pak W.L. Drosophila mutants with reduced rhodopsin content. Symp. Soc. Exp. Biol. 36 (1983) 477-501
21. Thummel C.S., and Pirrotta V. New pCaSpeR P-element vectors. Drosophila Information Newsletter vol. 2 (1991)
22. Vogt K., and Kirschfeld K. Chemical identity of the chromophores of fly visual pigment. Naturwissenschaften 71 (1984) 211-213
23. von Lintig J., and Vogt K. Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal. J. Biol. Chem. 275 (2000) 11915-11920
24. von Lintig J., Dreher A., Kiefer C., Wernet M.F., and Vogt K. Analysis of the blind Drosophila mutant ninaB identifies the gene encoding the key enzyme for vitamin A formation in vivo. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 1130-1135
25. Wang T., and Montell C. Rhodopsin formation in Drosophila is dependent on the PINTA retinoid-binding protein. J. Neurosci. 25 (2005) 5187-5194
26. Wyss A., Wirtz G.M., Woggon W.D., Brugger R., Wyss M., Friedlein A., Riss G., Bachmann H., and Hunziker W. Expression pattern and localization of beta,beta-carotene 15,15′-dioxygenase in different tissues. Biochem. J. 354 (2001) 521-529
27. Yan W., Jang G.F., Haeseleer F., Esumi N., Chang J., Kerrigan M., Campochiaro M., Campochiaro P., Palczewski K., and Zack D.J. Cloning and characterization of a human beta,beta-carotene-15,15′-dioxygenase that is highly expressed in the retinal pigment epithelium. Genomics 72 (2001) 193-202
28. Yao K.M., and White K. Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system. J. Neurochem. 63 (1994) 41-51