Blood pressure and vascular effects of leptin in humans

Metabolic Syndrome and Related Disorders

Volumn 5, Issue 1, 2007, Pages 63-68

  Brook, Robert D ^a,d   Bard, Robert L ^a   Bodary, Peter F ^a   Eitzman, Daniel T ^a   Rajagopalan, Sanjay ^b   Sun, Yan ^c   Depaoli, Alex M ^c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c AMGEN INC   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; PLACEBO; RECOMBINANT METHIONYL HUMAN LEPTIN; UNCLASSIFIED DRUG;

ADULT; ARTERY ENDOTHELIUM; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL; BRACHIAL ARTERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; FLOW MEDIATED DILATATION; HEART RATE; HUMAN; HUMAN EXPERIMENT; HYPERLEPTINEMIA; HYPERTENSION; MALE; NORMAL HUMAN; OBESITY; PARAMETER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE; WEIGHT REDUCTION;

EID: 34247333844     PISSN: 15404196     EISSN: None     Source Type: Journal    
DOI: 10.1089/met.2006.0023     Document Type: Article

References (8)

1. Grassi G. Leptin, sympathetic nervous system, and baroreflex function. Curr Hypertens Rep 2004;6: 236-240.
2. Mark AL, Correia MLG, Rahmouni K, Haynes WG. Selective leptin resistance: A new concept in leptin physiology with cardiovascular implications. J Hypertens 2002;20:1245-1250.
3. Ren J. Leptin and hyperleptinemia - From friend to foe for cardiovascular function. J Endocrinol 2004;181:1-10.
4. Rahmouni K, Morgan DA, Morgam GM, Mark AL, Haynes WG. Role of selective leptin resistance in diet-induced obesity hypertension. Diabetes 2005;54: 2012-2018.
5. Carlyle M, Jones OB, Kuo JJ, Hall JE. Chronic cardiovascular and renal actions of leptin. Role of adrenergic activity. Hypertension 2002;39(Part 2):496-501.
6. Rajagopalan S, Brook RD, Rubenfire M, Pitt E, Young E, Pitt B. Abnormal brachial artery flow-mediated vasodilatation in young adults with major depression. Am J Cardiol 2001;88:196-198.
7. Nakagawa K, Higashi Y, Sasaki S, Oshima T, Matsuura H, Chayama K. Leptin causes vasodilation in humans. Hypertens Res 2002;25:161-165.
8. Matsuda K, Teragawa H, Fukuda Y, Nakagawa K, Higashi Y, Chayama K. Leptin causes nitric-oxide independent coronary artery vasodilation in humans. Hypertens Res 2003;26:147-152.