Glutathione depletion induces differential apoptosis in cells of mouse retina, in vivo

Neuroscience Letters

Volumn 417, Issue 3, 2007, Pages 266-270

  Roh, Young Jung ^a   Moon, Cheil ^b   Kim, So Yeun ^b   Park, Myoung Hee ^a   Bae, Yong Chul ^b   Chun, Myung Hoon ^a   Moon, Jung Il ^a  

^a The Catholic University of Korea   (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

Apoptosis; BSO; Glutathione; Oxidative stress; Retina

Indexed keywords

BUTHIONINE SULFOXIMINE; GLUTATHIONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLINDNESS; CONTROLLED STUDY; DRUG TARGETING; GLUTATHIONE METABOLISM; HOST RESISTANCE; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RETINA BIPOLAR GANGLION CELL; RETINA NERVE CELL;

ANIMALS; ANTIMETABOLITES; APOPTOSIS; BUTHIONINE SULFOXIMINE; CELL COUNT; GLUTATHIONE; IN SITU NICK-END LABELING; MALE; MICE; MICE, INBRED C57BL; NEURONS; OXIDATIVE STRESS; PHOTORECEPTORS; RETINA; RETINAL DEGENERATION; UP-REGULATION;

EID: 34247279719     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.02.088     Document Type: Article

References (29)

1. Bridges C.C., Hu H., Miyauchi S., Siddaramappa U.N., Ganapathy M.E., Ignatowicz L., Maddox D.M., Smith S.B., and Ganapathy V. Induction of cystine-glutamate transporter xc-by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 45 (2004) 2906-2914
2. de Bernardo S., Canals S., Casarejos M.J., Solano R.M., Menendez J., and Mena M.A. Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures. J. Neurochem. 91 (2004) 667-682
3. Dowling J.E. Organization of vertebrate retinas. Invest. Ophthalmol. 9 (1970) 655-680
4. Dowling J.E. The Retina: An Approachable Part of the Brain (1987), Belknap-Harvard
5. Dringen R. Glutathione metabolism and oxidative stress in neurodegeneration. Eur. J. Biochem. 267 (2000) 4903
6. Dugan L.L., Sensi S.L., Canzoniero L.M., Handran S.D., Rothman S.M., Lin T.S., Goldberg M.P., and Choi D.W. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-d-aspartate. J. Neurosci. 15 (1995) 6377-6388
7. Finkel T. Oxygen radicals and signaling. Curr. Opin. Cell. Biol. 10 (1998) 248-253
8. Ganea E., and Harding J.J. Glutathione-related enzymes and the eye. Curr. Eye Res. 31 (2006) 1-11
9. Hall A.G. Review: the role of glutathione in the regulation of apoptosis. Eur. J. Clin. Invest. 29 (1999) 238-245
10. Halliwell B. Reactive oxygen species in living systems: source, biochemistry, and role in human disease. Am. J. Med. 91 (1991) 14S-22S
11. Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 59 (1992) 1609-1623
12. Knapp L.T., and Klann E. Role of reactive oxygen species in hippocampal long-term potentiation: contributory or inhibitory?. J. Neurosci. Res. 70 (2002) 1-7
13. Li Y., Roth S., Laser M., Ma J.X., and Crosson C.E. Retinal preconditioning and the induction of heat-shock protein 27. Invest. Ophthalmol. Vis. Sci. 44 (2003) 1299-1304
14. Lu S.C., Bao Y., Huang Z.Z., Sarthy V.P., and Kannan R. Regulation of gamma-glutamylcysteine synthetase subunit gene expression in retinal muller cells by oxidative stress. Invest. Ophthalmol. Vis. Sci. 40 (1999) 1776-1782
15. Mattson M.P., Duan W., Pedersen W.A., and Culmsee C. Neurodegenerative disorders and ischemic brain diseases. Apoptosis 6 (2001) 69-81
16. Moon J.I., Kim I.B., Gwon J.S., Park M.H., Kang T.H., Lim E.J., Choi K.R., and Chun M.H. Changes in retinal neuronal populations in the DBA/2J mouse. Cell Tissue Res. 320 (2005) 51-59
17. Moreno M.C., Campanelli J., Sande P., Sanez D.A., Keller Sarmiento M.I., and Rosenstein R.E. Retinal oxidative stress induced by high intraocular pressure. Free Radic. Biol. Med. 37 (2004) 803-812
18. Neufeld A.H., Shareef S., and Pena J. Cellular localization of neuronal nitric oxide synthase (NOS-1) in the human and rat retina. J. Comp. Neurol. 416 (2000) 269-275
19. Obrosova I.G., Fathallah L., and Greene D.A. Early changes in lipid peroxidation and anti-oxidative defense in diabetic rat retina: effect of dl-alpha-lipoic acid. Eur. J. Pharmacol. 398 (2000) 139-146
20. Papa S., and Skulachev V.P. Reactive oxygen species, mitochondria, apoptosis and aging. Mol. Cell Biochem. 174 (1997) 305-319
21. Park J.W., Moon C., Yun S., Kim S.Y., Bae Y.C., Chun M.H., and Moon J.I. Differential expression of heat shock protein mRNAs under in vivo glutathione depletion in the mouse retina. Neurosci. Lett. 413 (2007) 260-264
22. Ristoff E., Burstedt M., Larsson A., and Wachtmeister L. Progressive retinal dystrophy in two sisters with glutathione synthetase (GS) deficiency. J. Inherit. Metab. Dis. 30 (2007) 102
23. Rokutan K., Hirakawa T., Teshima S., Honda S., and Kishi K. Glutathione depletion impairs transcriptional activation of heat shock genes in primary cultures of guinea pig gastric mucosal cells. J. Clin. Invest. 97 (1996) 2242-2250
24. Rossi C., Strettoi E., and Galli-Resta L. The spatial order of horizontal cells is not affected by massive alterations in the organization of other retinal cells. J. Neurosci. 23 (2003) 9924-9928
25. Tanito M., Nishiyama A., Tanaka T., Masutani H., Nakamura H., Yodoi J., and Ohira A. Change of redox status and modulation by thiol replenishment in retinal photo-oxidative damage. Invest. Ophthalmol. Vis. Sci. 43 (2002) 2392-2400
26. Treichel J.L., Henry M.M., Skumatz C.M., Eells J.T., and Burke J.M. Anti-oxidants and ocular cell type differences in cytoprotection from formic acid toxicity in vitro. Toxicol. Sci. 82 (2004) 183-192
27. Wang X., Ng Y.K., and Tay S.S. Factors contributing to neuronal degeneration in retinas of experimental glaucomatous rats. J. Neurosci. Res. 82 (2005) 674-689
28. Yao K., Godwin A.K., Ozols R.F., Hamilton T.C., and O'Dwyer P.J. Variable baseline gamma-glutamylcysteine synthetase messenger RNA expression in peripheral mononuclear cells of cancer patients, and its induction by buthionine sulfoximine treatment. Cancer Res. 53 (1993) 3662-3666
29. Zhou Z.Y., Sugawara K., Hashi R., Muramoto K., Mawatari K., Matsukawa T., Liu Z.W., Devadas M., and Kato S. Reactive oxygen species uncouple external horizontal cells in the carp retina and glutathione couples them again. Neuroscience 102 (2001) 959-967